| Pub ID | Title | Author(s) | Year | Journal |
|---|
| 9321 | Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance | Sara Hägg (+4) | 2020 | Human Genetics |
| 5860 | The Health Impact of MAFLD, a Novel Disease Cluster of NAFLD, Is Amplified by the Integrated Effect of Fatty Liver Disease-Related Genetic Variants | Liu Z et al. | 2020 | Clin Gastroenterol Hepatol |
| 7485 | Deep learning-based unlearning of dataset bias for MRI harmonisation and confound removal | Nicola K. Dinsdale (+2) | 2020 | NeuroImage |
| 9320 | Relationship between Serum 25(OH)D and Depression: Causal Evidence from a Bi-Directional Mendelian Randomization Study | Anwar Mulugeta (+2) | 2020 | Nutrients |
| 5638 | Ranitidine Use and Cancer Risk: Results From UK Biobank | Elizabeth D Kantor (+5) | 2020 | Gastroenterology |
| 7259 | Association of red and processed meat consumption with cardiovascular morbidity and mortality in participants with and without obesity: A prospective cohort study | Jufen Zhang (+3) | 2020 | Clinical Nutrition |
| 4962 | Genetically determined risk of keratinocyte carcinoma and risk of other cancers | Jean Claude Dusingize (+9) | 2020 | International Journal of Epidemiology |
| 5939 | Ultra-processed food consumption and type 2 diabetes incidence: A prospective cohort study | Renata B Levy (+6) | 2020 | Clinical Nutrition |
| 9319 | Urate, Blood Pressure, and Cardiovascular Disease | Dipender Gill (+19) | 2020 | Hypertension |
| 3917 | A non-linear regression method for estimation of gene-environment heritability | Matthew Kerin (+1) | 2020 | Bioinformatics |
| 5869 | The Interplay Between Titin, Polygenic Risk, and Modifiable Cardiovascular Risk Factors in Atrial Fibrillation | Kate Huang (+4) | 2020 | Canadian Journal of Cardiology |
| 4553 | Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort | Kyle Gettler (+22) | 2020 | Gastroenterology |
| 7486 | Risk stratification for proton pump inhibitor-associated type 2 diabetes: a population-based cohort study | Qiangsheng He (+5) | 2020 | Gut |
| 5812 | The association of serum lipid and lipoprotein levels with total and differential leukocyte counts: Results of a cross-sectional and longitudinal analysis of the UK Biobank | Bradley Tucker (+6) | 2020 | Atherosclerosis |
| 7487 | The human hippocampus and its subfield volumes across age, sex and APOE e4 status | Michele Veldsman (+4) | 2020 | Brain Communications |
| 4665 | Development and Validation of a Risk Prediction Model for Esophageal Squamous Cell Carcinoma Using Cohort Studies. | Qiao-Li Wang (+4) | 2020 | The American Journal of Gastroenterology |
| 9317 | Genome-wide association study of vegetarianism in UK Biobank identifies association with VRK2 | Georgina K. Fensom (+4) | 2020 | Wellcome Open Research |
| 9318 | Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease | Jonas B. Nielsen (+106) | 2020 | Nature Communications |
| 12887 | Cystic fibrosis F508del carriers and cancer risk: Results from the UK Biobank | Zhuqing Shi (+8) | 2020 | International Journal of Cancer |
| 3389 | Pharmacogenetics at Scale: An Analysis of the UK Biobank | Gregory McInnes (+5) | 2020 | Clinical Pharmacology & Therapeutics |
| 4422 | Cardiovascular magnetic resonance reference values of mitral and tricuspid annular dimensions: the UK Biobank cohort | Fabrizio Ricci (+13) | 2020 | Journal of Cardiovascular Magnetic Resonance |
| 4173 | Association of Antioxidants Use with All-Cause and Cause-Specific Mortality: A Prospective Study of the UK Biobank | Inken Behrendt (+2) | 2020 | Antioxidants |
| 7600 | LDpred2: better, faster, stronger | Florian Privé (+2) | 2020 | Bioinformatics |
| 4135 | Association Between Depressive Symptoms and Incident Cardiovascular Diseases | Harshfield EL et al. | 2020 | JAMA |
| 5248 | Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis | Corbin Quick (+4) | 2020 | PLOS Genetics |
| 5832 | The default network of the human brain is associated with perceived social isolation | R. Nathan Spreng (+15) | 2020 | Nature Communications |
| 3617 | Evidence of horizontal indirect genetic effects in humans | Charley Xia (+3) | 2020 | Nature Human Behaviour |
| 5150 | Host genetic effects in pneumonia | Hung-Hsin Chen (+17) | 2020 | American Journal of Human Genetics |
| 4496 | Circulating insulin-like growth factor-I, total and free testosterone concentrations and prostate cancer risk in 200 000 men in UK Biobank | Eleanor L. Watts (+13) | 2020 | International Journal of Cancer |
| 4857 | Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants | Xinyi Jiang (+6) | 2020 | Communications Biology |
| 7322 | Associations of weight changes with all-cause, cancer and cardiovascular mortality: A prospective cohort study | Jufen Zhang (+3) | 2020 | Public Health in Practice |
| 9316 | Genetic mechanisms of critical illness in COVID-19 | Johnny Millar (+1413) | 2020 | Nature |
| 5771 | Sparse Project VCF: efficient encoding of population genotype matrices | Michael F Lin (+3) | 2020 | Bioinformatics |
| 7321 | Natural history of tinnitus in adults: a cross-sectional and longitudinal analysis | Piers Dawes (+3) | 2020 | BMJ Open |
| 9315 | Whole-genome sequencing analysis of the cardiometabolic proteome | Arthur Gilly (+13) | 2020 | Nature Communications |
| 3788 | Analysis of 50,000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral | David Curtis | 2020 | Journal of Affective Disorders |
| 3823 | Adherence to a healthy lifestyle and multiple sclerosis: a case-control study from the UK Biobank | Nicola Veronese (+12) | 2020 | Nutritional Neuroscience |
| 4260 | Associations Between Hearing Health and Well-Being in Unilateral Hearing Impairment | Robert H. Pierzycki (+5) | 2020 | Ear & Hearing |
| 12888 | Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants | Miriam Mutambudzi (+20) | 2020 | Occupational and Environmental Medicine |
| 3903 | A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility | Nima C. Emami (+25) | 2020 | Cancer Research |
| 3930 | A population scale analysis of rare SNCA variation in the UK Biobank | Cornelis Blauwendraat (+7) | 2020 | Neurobiology of Disease |
| 5943 | Understanding ethnic inequalities in hearing health in the UK: a cross-sectional study of the link between language proficiency and performance on the Digit Triplet Test | Taylor H et al. | 2020 | BMJ Open |
| 7488 | PERHAPS: Paired-End short Reads-based HAPlotyping from next-generation Sequencing data | Jie Huang (+6) | 2020 | Briefings in Bioinformatics |
| 8192 | Diabetes and COVID-19-Related Mortality in Women and Men in the UK Biobank: Comparisons With Influenza/Pneumonia and Coronary Heart Disease | Marit de Jong (+2) | 2020 | Diabetes Care |
| 9313 | Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus | M. Abdullah Said (+3) | 2020 | Journal of the American Heart Association |
| 9314 | Cerebral small vessel disease genomics and its implications across the lifespan | Muralidharan Sargurupremraj (+115) | 2020 | Nature Communications |
| 12889 | The effect of angiotensin-converting enzyme levels on COVID-19 susceptibility and severity: a Mendelian randomization study | Guillaume Butler-Laporte (+8) | 2020 | International Journal of Epidemiology |
| 4568 | Comparative analysis, applications, and interpretation of electronic health record-based stroke phenotyping methods | Thangaraj PM et al. | 2020 | BioData Min |
| 7632 | Improving the informativeness of Mendelian disease-derived pathogenicity scores for common disease | Samuel S. Kim (+5) | 2020 | Nature Communications |
| 7489 | Physical activity and COVID-19: an observational and Mendelian randomisation study | Xiaomeng Zhang (+8) | 2020 | Journal of Global Health |
| 12890 | Phenome-wide association study in adult coeliac disease: role of HLA subtype | Carolin V. Schneider (+4) | 2020 | Alimentary Pharmacology & Therapeutics |
| 4761 | Effects of Thyroid Status on Regional Brain Volumes: A Diagnostic and Genetic Imaging Study in UK Biobank | Tom Chambers (+7) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 5723 | Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis | Tricia M. Peters (+14) | 2020 | Diabetes Care |
| 5535 | Phenotype risk scores (PheRS) for pancreatic cancer using time-stamped electronic health record data: Discovery and validation in two large biobanks | Maxwell Salvatore (+7) | 2020 | Journal of Biomedical Informatics |
| 4980 | Genetically proxied milk consumption and risk of colorectal, bladder, breast, and prostate cancer: a two-sample Mendelian randomization study | Susanna C. Larsson (+7) | 2020 | BMC Medicine |
| 5222 | Inclusion of variants discovered from diverse populations improves polygenic risk score transferability | Taylor B. Cavazos (+1) | 2020 | Human Genetics and Genomics Advances |
| 3404 | Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank | Ferguson AC et al. | 2020 | J Hypertens |
| 3665 | Kidney segmentation in neck-to-knee body MRI of 40,000 UK Biobank participants | Taro Langner (+10) | 2020 | Scientific Reports |
| 3763 | Cancer and Cardiovascular Risk in Women With Hypertensive Disorders of Pregnancy Carrying a Common IGF1R Variant | Powell MJ et al. | 2020 | Mayo Clin Proc |
| 3945 | A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems | Denaxas S et al. | 2020 | JAMIA Open |
| 4218 | Association of physical activity and sedentary behavior with type 2 diabetes and glycemic traits: a two-sample Mendelian randomization study | Meisinger C et al. | 2020 | BMJ Open Diabetes Res Care |
| 4248 | Associations Between Alcohol Intake and Genetic Predisposition With Atrial Fibrillation Risk in a National Biobank | Halford JL et al. | 2020 | Circ Genom Precis Med |
| 4360 | Birth weight is positively associated with adult osteoporosis risk: observational and Mendelian randomization studies | Xing-Hao Yu (+3) | 2020 | Journal of Bone and Mineral Research |
| 4412 | Cardiac Imaging of Aortic Valve Area From 34 287 UK Biobank Participants Reveals Novel Genetic Associations and Shared Genetic Comorbidity With Multiple Disease Phenotypes | Córdova-Palomera A et al. | 2020 | Circ Genom Precis Med |
| 4475 | Characterization of human papillomavirus (HPV) 16 E6 seropositive individuals without HPV-associated malignancies after 10 years of follow-up in the UK Biobank | Brenner N et al. | 2020 | EBioMedicine |
| 4500 | Circulating Lipoprotein Lipids, Apolipoproteins and Ischemic Stroke | Yuan S et al. | 2020 | Ann Neurol |
| 4745 | Education, biological ageing, all-cause and cause-specific mortality and morbidity: UK biobank cohort study | Chadeau-Hyam M et al. | 2020 | EClinicalMedicine |
| 4818 | Examining the effect of smoking on suicidal ideation and attempts: triangulation of epidemiological approaches | Harrison R et al. | 2020 | Br J Psychiatry |
| 4863 | Frailty index and all-cause and cause-specific mortality in Chinese adults: a prospective cohort study | Fan J et al. | 2020 | Lancet Public Health |
| 4937 | Genetic risk of obesity as a modifier of associations between neighbourhood environment and body mass index: an observational study of 335 046 UK Biobank participants | Mason KE et al. | 2020 | BMJ Nutr Prev Health |
| 5207 | Impact of road traffic noise on obesity measures: Observational study of three European cohorts | Cai Y et al. | 2020 | Environ Res |
| 5450 | Network and pathway expansion of genetic disease associations identifies successful drug targets | Aidan MacNamara (+6) | 2020 | Scientific Reports |
| 5548 | Physical activity, dietary protein and insulin-like growth factor 1: Cross-sectional analysis utilising UK Biobank | Gulick CN et al. | 2020 | Growth Horm IGF Res |
| 5725 | Sex hormones, SHBG and risk of colon and rectal cancer among men and women in the UK Biobank | Peila R et al. | 2020 | Cancer Epidemiol |
| 5748 | Short or Long Sleep Duration and CKD: A Mendelian Randomization Study | Park S et al. | 2020 | J Am Soc Nephrol |
| 5775 | Spontaneous Coronary Artery Dissection: Insights on Rare Genetic Variation From Genome Sequencing | Carss KJ et al. | 2020 | Circ Genom Precis Med |
| 6008 | Whole-brain functional connectivity correlates of obesity phenotypes | Park BY et al. | 2020 | Hum Brain Mapp |
| 8196 | Simultaneous high-probability bounds on the false discovery proportion in structured, regression and online settings | Eugene Katsevich (+1) | 2020 | The Annals of Statistics |
| 10343 | Identifying Causes of Fracture Beyond Bone Mineral Density: Evidence From Human Genetics | Tianyuan Lu (+3) | 2020 | Journal of Bone and Mineral Research |
| 12891 | Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank | Elizabeth M. Curtis (+12) | 2020 | Journal of Bone and Mineral Research |
| 12892 | Shared Genetic Architecture Between Rheumatoid Arthritis and Varying Osteoporotic Phenotypes | Melody Kasher (+5) | 2020 | Journal of Bone and Mineral Research |
| 12893 | Machine Learning-Derived Acetabular Dysplasia and Cam Morphology Are Features of Severe Hip Osteoarthritis: Findings From UK Biobank | Monika Frysz (+9) | 2020 | Journal of Bone and Mineral Research |
| 12894 | Is Environmental and Occupational Particulate Air Pollution Exposure Related to Type-2 Diabetes and Dementia? A Cross-Sectional Analysis of the UK Biobank | Eirini Dimakakou (+3) | 2020 | International Journal of Environmental Research and Public Health |
| 3624 | Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations | Juba Nait Saada (+6) | 2020 | Nature Communications |
| 4632 | Deep Learning-Based Detection and Correction of Cardiac MR Motion Artefacts During Reconstruction for High-Quality Segmentation | Ilkay Oksuz (+8) | 2020 | IEEE Transactions on Medical Imaging |
| 5676 | Retinal asymmetry in multiple sclerosis | Axel Petzold (+78) | 2020 | Brain |
| 4271 | Associations between serum uric acid and hepatobiliary-pancreatic cancer: A cohort study | Huang CF et al. | 2020 | World J Gastroenterol |
| 5524 | Performance of Three Inherited Risk Measures for Predicting Prostate Cancer Incidence and Mortality: A Population-based Prospective Analysis | Zhuqing Shi (+13) | 2020 | European Urology |
| 3845 | Evaluating human autosomal loci for sexually antagonistic viability selection in two large biobanks | Katja R Kasimatis (+5) | 2020 | Genetics |
| 7353 | Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction | Linda Kachuri (+7) | 2020 | Nature Communications |
| 12895 | Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health | Satu Strausz (+22) | 2020 | European Respiratory Journal |
| 4368 | Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis | Stanley Teleka (+7) | 2020 | PLOS ONE |
| 4929 | Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women | Valgerdur Steinthorsdottir (+74) | 2020 | Nature Communications |
| 5301 | Large genome-wide association study identifies three novel risk variants for restless legs syndrome | Maria Didriksen (+33) | 2020 | Communications Biology |
| 5854 | The genetic architecture of sporadic and multiple consecutive miscarriage | Laisk T et al. | 2020 | Nat Commun |
| 4201 | Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy | Atkins JL et al. | 2020 | JAMA |
| 4917 | Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study | Klinedinst BS et al. | 2020 | J Alzheimers Dis |
| 5786 | Super-variants identification for brain connectivity | Ting Li (+3) | 2020 | Human Brain Mapping |
| 5836 | The Effect of Blood Lipids on the Left Ventricle: A Mendelian Randomization Study | Aung N et al. | 2020 | J Am Coll Cardiol |
| 3922 | A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population | Catherine Tcheandjieu (+8) | 2020 | PLOS Genetics |
| 5520 | Patterns of multimorbidity and their effects on adverse outcomes in rheumatoid arthritis: a study of 5658 UK Biobank participants | Ross McQueenie (+9) | 2020 | BMJ Open |
| 5866 | The Impact of Periodontal Disease on Hospital Admission and Mortality During COVID-19 Pandemic | Harriet Larvin (+3) | 2020 | Frontiers in Medicine |
| 5028 | Genome-wide association study identifies a role for the progesterone receptor in benign prostatic hyperplasia risk | Weiqiang Li (+1) | 2020 | Prostate Cancer and Prostatic Diseases |
| 5465 | No association between SCN9A and monogenic human epilepsy disorders | James Fasham (+9) | 2020 | PLOS Genetics |
| 8197 | Marginalized Frailty-Based Illness-Death Model: Application to the UK-Biobank Survival Data | Malka Gorfine (+4) | 2020 | Journal of the American Statistical Association |
| 5304 | Large-scale analysis of iliopsoas muscle volumes in the UK Biobank | Julie A. Fitzpatrick (+6) | 2020 | Scientific Reports |
| 5407 | Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study | Frederick K Ho (+12) | 2020 | BMJ Open |
| 4425 | Cardiovascular risk factors and body composition in adults with achondroplasia | Svein O. Fredwall (+9) | 2020 | Genetics in Medicine |
| 3843 | Interactions Between Age, Sex, Menopause, and Brain Structure at Midlife: A UK Biobank Study | Stephanie Than (+10) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 3963 | Accelerated MRI-predicted brain ageing and its associations with cardiometabolic and brain disorders | Arinbjörn Kolbeinsson (+6) | 2020 | Scientific Reports |
| 4519 | Clinical, regional, and genetic characteristics of Covid-19 patients from UK Biobank | David A. Kolin (+3) | 2020 | PLOS ONE |
| 3150 | Functionally informed fine-mapping and polygenic localization of complex trait heritability | Omer Weissbrod (+13) | 2020 | Nature Genetics |
| 3982 | Adherence to a Healthy Sleep Pattern and Incident Heart Failure: A Prospective Study of 408802 UK Biobank Participants | Xiang Li (+6) | 2020 | Circulation |
| 5039 | Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors | Mark K. Bakker (+73) | 2020 | Nature Genetics |
| 5516 | Pathological Cluster Identification by Unsupervised Analysis in 3,822 UK Biobank Cardiac MRIs | Qiao Zheng (+4) | 2020 | Frontiers in Cardiovascular Medicine |
| 9272 | Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis | Desana Kocevska (+72) | 2020 | Nature Human Behaviour |
| 5397 | Microstructural differences in white matter tracts across middle to late adulthood: a diffusion MRI study on 7167 UK Biobank participants | Wen-Yih Isaac Tseng (+6) | 2020 | Neurobiology of Aging |
| 4544 | Collider bias undermines our understanding of COVID-19 disease risk and severity | Gareth J. Griffith (+13) | 2020 | Nature Communications |
| 4956 | Genetic, lifestyle, and health-related characteristics of adults without celiac disease who follow a gluten-free diet: a population-based study of 124,447 participants | Thomas J Littlejohns (+7) | 2020 | American Journal of Clinical Nutrition |
| 5266 | Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury | Schneider KM et al. | 2020 | Cell Mol Gastroenterol Hepatol |
| 5434 | Multiple lifestyle factors and depressed mood: a cross-sectional and longitudinal analysis of the UK Biobank (N = 84,860) | Jerome Sarris (+9) | 2020 | BMC Medicine |
| 3959 | A unified linear mixed model for familial relatedness and population structure in genetic association studies | Nicholas DeVogel (+4) | 2020 | Genetic Epidemiology |
| 4451 | Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study | Nay Aung (+3) | 2020 | Frontiers in Genetics |
| 5232 | Individual and combined associations between cardiorespiratory fitness and grip strength with common mental disorders: a prospective cohort study in the UK Biobank | Aaron A. Kandola (+4) | 2020 | BMC Medicine |
| 4584 | Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank | Fanny Petermann-Rocha (+16) | 2020 | BMC Medicine |
| 4839 | Exploring the Role of Contactins across Psychological, Psychiatric and Cardiometabolic Traits within UK Biobank | Julia Morris (+11) | 2020 | Genes |
| 3748 | Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes | Skol AD et al. | 2020 | Elife |
| 5331 | Little Evidence of Modified Genetic Effect of rs16969968 on Heavy Smoking Based on Age of Onset of Smoking | Christine Adjangba (+4) | 2020 | Nicotine & Tobacco Research |
| 5821 | The bidirectional association between sleep and physical activity: A 6.9 years longitudinal analysis of 38,601 UK Biobank participants | Bo-Huei Huang (+4) | 2020 | Preventive Medicine |
| 3400 | Associations between Alzheimer's disease polygenic risk scores and hippocampal subfield volumes in 17,161 UK Biobank participants | Heidi Foo (+6) | 2020 | Neurobiology of Aging |
| 4595 | Confidence Sets for Cohen's d effect size images | Alexander Bowring (+3) | 2020 | NeuroImage |
| 4565 | Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies | Lind L et al. | 2020 | PLoS One |
| 5155 | Human leukocyte antigen associations with renal function among ethnic minorities in the United Kingdom | Marcus Lowe (+8) | 2020 | HLA |
| 5284 | Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants | Ho FK et al. | 2020 | PLoS One |
| 4505 | Circulating Sex Hormones Are Associated With Gastric and Colorectal Cancers but Not Esophageal Adenocarcinoma in the UK Biobank. | Úna C McMenamin (+7) | 2020 | The American Journal of Gastroenterology |
| 4838 | Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective | Frouin A et al. | 2020 | Front Genet |
| 5651 | Recent consumption of a caffeine-containing beverage and serum biomarkers of cardiometabolic function in the UK Biobank. | Marilyn C Cornelis | 2020 | British Journal Of Nutrition |
| 3732 | Serum lipid profiles and risk of colorectal cancer: a prospective cohort study in the UK Biobank | Zhe Fang (+2) | 2020 | British Journal of Cancer |
| 4826 | Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits | Bryan C. Quach (+45) | 2020 | Nature Communications |
| 5468 | No Evidence for Passive Gene-Environment Correlation or the Influence of Genetic Risk for Psychiatric Disorders on Adult Body Composition via the Adoption Design | Avina K. Hunjan (+5) | 2020 | Behavior Genetics |
| 9271 | All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes | Alice E. Hughes (+9) | 2020 | Wellcome Open Research |
| 3731 | Circulating liver function markers and colorectal cancer risk: A prospective cohort study in the UK Biobank | Ming-ming He (+12) | 2020 | International Journal of Cancer |
| 5635 | Radiomics Signatures of Cardiovascular Risk Factors in Cardiac MRI: Results From the UK Biobank | Irem Cetin (+8) | 2020 | Frontiers in Cardiovascular Medicine |
| 3111 | Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes | van der Meer D et al. | 2020 | Mol Psychiatry |
| 3546 | Genetically raised serum bilirubin levels and lung cancer: a cohort study and Mendelian randomisation using UK Biobank | Horsfall LJ et al. | 2020 | Thorax |
| 3803 | Seasonality and season of birth effect in the UK Biobank cohort | Didikoglu A et al. | 2020 | Am J Hum Biol |
| 4214 | Association of obesity and its genetic predisposition with the risk of severe COVID-19: Analysis of population-based cohort data | Zhu Z et al. | 2020 | Metabolism |
| 4493 | Circulating Insulin-Like Growth Factor-1 and Risk of Total and 19 Site-Specific Cancers: Cohort Study Analyses from the UK Biobank | Frank Qian (+1) | 2020 | Cancer Epidemiology Biomarkers & Prevention |
| 4672 | Diabetes, glycaemic control, and risk of COVID-19 hospitalisation: Population-based, prospective cohort study | Hamer M et al. | 2020 | Metabolism |
| 4723 | Do Serum Urate-associated Genetic Variants Influence Gout Risk in People Taking Diuretics? Analysis of the UK Biobank | Narang RK et al. | 2020 | J Rheumatol |
| 5067 | Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease | Hindy G et al. | 2020 | Arterioscler Thromb Vasc Biol |
| 5158 | Hypertension is associated with reduced hippocampal connectivity and impaired memory | Feng R et al. | 2020 | EBioMedicine |
| 5285 | Is periodontitis a risk factor for ischaemic stroke, coronary artery disease and subclinical atherosclerosis? A Mendelian randomization study | Bell S et al. | 2020 | Atherosclerosis |
| 5415 | Morning diurnal preference and food intake: a Mendelian randomization study | Hassan S Dashti (+3) | 2020 | American Journal of Clinical Nutrition |
| 5483 | Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry | Clifford RE et al. | 2020 | JAMA Otolaryngol Head Neck Surg |
| 5602 | Pre-pandemic psychiatric disorders and risk of COVID-19: a UK Biobank cohort analysis | Yang H et al. | 2020 | Lancet Healthy Longev |
| 5792 | Systemic evaluation of the relationship between psoriasis, psoriatic arthritis and osteoporosis: observational and Mendelian randomisation study | Xia J et al. | 2020 | Ann Rheum Dis |
| 5870 | The joint association of sarcopenia and frailty with incidence and mortality health outcomes: A prospective study | Fanny Petermann-Rocha (+4) | 2020 | Clinical Nutrition |
| 7490 | Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by glioma | Ayan S Mandal (+3) | 2020 | Brain |
| 7633 | Polygenic Scores for Height in Admixed Populations | Bárbara D Bitarello (+1) | 2020 | G3: Genes, Genomes, Genetics |
| 5080 | Genotype-Based Gene Expression in Colon Tissue - Prediction Accuracy and Relationship with the Prognosis of Colorectal Cancer Patients | Heike Deutelmoser (+12) | 2020 | International Journal of Molecular Sciences |
| 5388 | Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline | Mathias Gorski (+178) | 2020 | Kidney International |
| 7260 | Association of Timing and Balance of Physical Activity and Rest/Sleep With Risk of COVID-19: A UK Biobank Study | Alex V Rowlands (+11) | 2020 | Mayo Clinic Proceedings |
| 12897 | Metabolic shift underlies recovery in reversible infantile respiratory chain deficiency | Denisa Hathazi (+37) | 2020 | The EMBO Journal |
| 4590 | Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events | Daniela Zanetti (+3) | 2020 | Circulation Genomic and Precision Medicine |
| 5049 | Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival | Iain R. Timmins (+5) | 2020 | Communications Biology |
| 9270 | LDBlockShow: a fast and convenient tool for visualizing linkage disequilibrium and haplotype blocks based on variant call format files | Shan-Shan Dong (+5) | 2020 | Briefings in Bioinformatics |
| 5234 | Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening | Tianyuan Lu (+5) | 2020 | Genetics in Medicine |
| 5056 | Genome-Wide Gene-by-Smoking Interaction Study of Chronic Obstructive Pulmonary Disease | Woori Kim (+12) | 2020 | American Journal of Epidemiology |
| 5871 | The landscape of host genetic factors involved in immune response to common viral infections | Linda Kachuri (+8) | 2020 | Genome Medicine |
| 4009 | Age, menstruation history, and the brain | Ambikairajah A et al. | 2020 | Menopause |
| 4788 | Estimating indirect parental genetic effects on offspring phenotypes using virtual parental genotypes derived from sibling and half sibling pairs | Liang-Dar Hwang (+9) | 2020 | PLOS Genetics |
| 5733 | Sex-Specific Genetically Predicted Iron Status in relation to 12 Vascular Diseases: A Mendelian Randomization Study in the UK Biobank | Yang F et al. | 2020 | Biomed Res Int |
| 3870 | A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank | Junyang Qian (+7) | 2020 | PLOS Genetics |
| 4107 | Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization Approaches | Yixin Gao (+5) | 2020 | Frontiers in Genetics |
| 5852 | The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study | Yu-Fang Pei (+6) | 2020 | Communications Biology |
| 7491 | Early-Life Factors and Risk of Multiple Sclerosis: An MR-EWAS | Lazaros Belbasis (+3) | 2020 | Neuroepidemiology |
| 9269 | MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk | Ida Surakka (+25) | 2020 | Nature Communications |
| 3383 | Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes | Derek W. Brown (+5) | 2020 | PLOS Genetics |
| 4822 | Exome sequencing and characterization of 49,960 individuals in the UK Biobank | Cristopher V. Van Hout (+50) | 2020 | Nature |
| 5552 | Plasma lipids and risk of aortic valve stenosis: a Mendelian randomization study | Nazarzadeh M et al. | 2020 | Eur Heart J |
| 5616 | Prospective associations between vitamin D and depression in middle-aged adults: findings from the UK Biobank cohort | Amy Ronaldson (+6) | 2020 | Psychological Medicine |
| 9268 | Detect and correct bias in multi-site neuroimaging datasets | Christian Wachinger (+3) | 2020 | Medical Image Analysis |
| 4075 | Anthropometry, body fat composition and reproductive factors and risk of oesophageal and gastric cancer by subtype and subsite in the UK Biobank cohort | Harinakshi Sanikini (+5) | 2020 | PLOS ONE |
| 4358 | Large-scale biometry with interpretable neural network regression on UK Biobank body MRI | Taro Langner (+3) | 2020 | Scientific Reports |
| 5755 | Sleep trajectories and mediators of poor sleep: findings from the longitudinal analysis of 41,094 participants of the UK Biobank cohort | Yaqoot Fatima (+6) | 2020 | Sleep Medicine |
| 2812 | Links between air pollution and COVID-19 in England | Marco Travaglio (+5) | 2020 | Environmental Pollution |
| 3973 | Accurate brain age prediction with lightweight deep neural networks | Han Peng (+4) | 2020 | Medical Image Analysis |
| 4328 | Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms | Xinyue Li (+1) | 2020 | PLOS Genetics |
| 5938 | Ultra-processed food consumption and risk of obesity: a prospective cohort study of UK Biobank | Fernanda Rauber (+6) | 2020 | European Journal of Nutrition |
| 5824 | The Causal Effects of Blood Iron and Copper on Lipid Metabolism Diseases: Evidence from Phenome-Wide Mendelian Randomization Study | Jingqi Zhou (+6) | 2020 | Nutrients |
| 9267 | Germline variants are associated with increased primary melanoma tumor thickness at diagnosis | Ernest Mangantig (+19) | 2020 | Human Molecular Genetics |
| 4759 | Effects of lifelong testosterone exposure on health and disease: a Mendelian randomization study | Pedrum Mohammadi-Shemirani (+5) | 2020 | eLife |
| 5712 | Serum Testosterone is Inversely and Sex Hormone-binding Globulin is Directly Associated with All-cause Mortality in Men | Bu B Yeap (+19) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 5721 | Sex differences in the association between major risk factors and the risk of stroke in the UK Biobank cohort study | Sanne A E Peters (+3) | 2020 | Neurology |
| 9266 | Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals | Lasse Folkersen (+82) | 2020 | Nature Metabolism |
| 4132 | Association between childhood trauma and risk for obesity: a putative neurocognitive developmental pathway | Qiang Luo (+34) | 2020 | BMC Medicine |
| 7492 | Toxoplasma gondii seropositivity and serointensity and cognitive function in adults | Shawn D. Gale (+5) | 2020 | PLOS Neglected Tropical Diseases |
| 6007 | Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants | Xutong Zhao (+68) | 2020 | Nature Communications |
| 7352 | Living alone, loneliness and lack of emotional support as predictors of suicide and self-harm: A nine-year follow up of the UK Biobank cohort | Richard J. Shaw (+9) | 2020 | Journal of Affective Disorders |
| 12898 | Dietary Fiber, Genetic Variations of Gut Microbiota-derived Short-chain Fatty Acids, and Bone Health in UK Biobank | Tao Zhou (+5) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 5592 | Predicting the effect of statins on cancer risk using genetic variants from a Mendelian randomization study in the UK Biobank | Paul Carter (+6) | 2020 | eLife |
| 7299 | Probabilistic Estimation of Identity by Descent Segment Endpoints and Detection of Recent Selection | Sharon R. Browning (+1) | 2020 | American Journal of Human Genetics |
| 9265 | Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses | Jue-Sheng Ong (+14) | 2020 | International Journal of Cancer |
| 4749 | Effect of Citric Acid Cycle Genetic Variants and Their Interactions with Obesity, Physical Activity and Energy Intake on the Risk of Colorectal Cancer: Results from a Nested Case-Control Study in the UK Biobank | Sooyoung Cho (+3) | 2020 | Cancers |
| 9264 | Pathogenic variants in actionable MODY genes are associated with type 2 diabetes | Amélie Bonnefond (+26) | 2020 | Nature Metabolism |
| 5488 | Obesity as a risk factor for COVID-19 mortality in women and men in the UK biobank: Comparisons with influenza/pneumonia and coronary heart disease | Sanne A. E. Peters (+2) | 2020 | Diabetes Obesity and Metabolism |
| 4807 | Evaluation of a genetic risk score for severity of COVID-19 using human chromosomal-scale length variation | Christopher Toh (+1) | 2020 | Human Genomics |
| 7493 | Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons | Samar Khoury (+24) | 2020 | Sleep |
| 9240 | Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD) | Christina Kiel (+4) | 2020 | Cells |
| 5377 | Mendelian randomization provides evidence for a causal effect of higher serum IGF-1 concentration on risk of hip and knee osteoarthritis | April Hartley (+6) | 2020 | Rheumatology |
| 3724 | Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease | Trinder M et al. | 2020 | JAMA Cardiol |
| 5756 | Sleep, major depressive disorder, and Alzheimer disease: A Mendelian randomization study | Huang J et al. | 2020 | Neurology |
| 5874 | The mediating role of comorbid conditions in the association between type 2 diabetes and cognition: A cross-sectional observational study using the UK Biobank cohort | Victoria Whitelock (+4) | 2020 | Psychoneuroendocrinology |
| 4936 | Genetic Risk of Alzheimer's Disease and Sleep Duration in Non-Demented Elders | Yue Leng (+4) | 2020 | Annals of Neurology |
| 5345 | Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older UK Biobank Participants | Luke C. Pilling (+8) | 2020 | Journal of the American Geriatrics Society |
| 9239 | Recovering from missing data in population imaging - Cardiac MR image imputation via conditional generative adversarial nets | Yan Xia (+7) | 2020 | Medical Image Analysis |
| 2589 | Dairy consumption and risk of falls in 2 European cohorts of older adults | Machado-Fragua MD et al. | 2020 | Clin Nutr |
| 3154 | Prediction of systemic biomarkers from retinal photographs: development and validation of deep-learning algorithms | Rim TH et al. | 2020 | Lancet Digit Health |
| 3445 | Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank | Brcic L et al. | 2020 | J Med Genet |
| 3604 | Meat intake and cancer risk: prospective analyses in UK Biobank | Knuppel A et al. | 2020 | Int J Epidemiol |
| 3654 | Serum free testosterone and asthma, asthma hospitalisations and lung function in British adults | Han YY et al. | 2020 | Thorax |
| 3745 | Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study based on a community sample | Batty GD et al. | 2020 | Brain Behav Immun |
| 4217 | Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study | Zhou H et al. | 2020 | JAMA Psychiatry |
| 4554 | Common APOC3 variants are associated with circulating ApoC-III and VLDL cholesterol but not with total apolipoprotein B and coronary artery disease | Silbernagel G et al. | 2020 | Atherosclerosis |
| 4613 | COVID-19 is an emergent disease of aging | Didac Santesmasses (+9) | 2020 | Aging Cell |
| 4754 | Effects of atmospheric particulate matter pollution on sleep disorders and sleep duration: a cross-sectional study in the UK biobank | Li L et al. | 2020 | Sleep Med |
| 4813 | Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study | Wootton RE et al. | 2020 | Psychol Med |
| 5024 | Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1 | Innes H et al. | 2020 | Gastroenterology |
| 5070 | Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy | Krebs K et al. | 2020 | Am J Hum Genet |
| 5108 | Habitual Coffee and Tea Consumption and Cardiometabolic Biomarkers in the UK Biobank: The Role of Beverage Types and Genetic Variation | Marilyn C Cornelis (+1) | 2020 | Journal of Nutrition |
| 5186 | IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank | Sukcharoen K et al. | 2020 | Kidney Int Rep |
| 5211 | Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980 | Maud Miguet (+3) | 2020 | International Journal of Environmental Research and Public Health |
| 5494 | Observational and Genetic Associations of Body Mass Index and Hepatobiliary Diseases in a Relatively Lean Chinese Population | Pang Y et al. | 2020 | JAMA Netw Open |
| 5515 | Parkinson's disease determinants, prediction and gene-environment interactions in the UK Biobank | Jacobs BM et al. | 2020 | J Neurol Neurosurg Psychiatry |
| 5517 | Pathway Analysis of Renal Cell Carcinoma Genome-Wide Association Studies Identifies Novel Associations | Purdue MP et al. | 2020 | Cancer Epidemiol Biomarkers Prev |
| 5565 | Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia | Trinder M et al. | 2020 | Circ Genom Precis Med |
| 5681 | Risk factors for positive and negative COVID-19 tests: a cautious and in-depth analysis of UK biobank data | Chadeau-Hyam M et al. | 2020 | Int J Epidemiol |
| 5825 | The causal effects of health conditions and risk factors on social and socioeconomic outcomes: Mendelian randomization in UK Biobank | Harrison S et al. | 2020 | Int J Epidemiol |
| 4900 | Genetic basis of falling risk susceptibility in the UK Biobank Study | Katerina Trajanoska (+14) | 2020 | Communications Biology |
| 5632 | Quantifying the Predictive Performance of Objectively Measured Physical Activity on Mortality in the UK Biobank | Andrew Leroux (+6) | 2020 | The Journals of Gerontology Series A |
| 9238 | Sex- and age-specific genetic analysis of chronic back pain. | Maxim B Freidin (+16) | 2020 | Pain |
| 4399 | Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank: CADASIL to nonpenetrance | Rutten JW et al. | 2020 | Neurology |
| 7261 | Fast Lasso method for large-scale and ultrahigh-dimensional Cox model with applications to UK Biobank | Ruilin Li (+7) | 2020 | Biostatistics |
| 9237 | A genotype-first approach to exploring Mendelian cardiovascular traits with clear external manifestations | Brittany M. Wenger (+10) | 2020 | Genetics in Medicine |
| 3992 | Adults With Mild-to-Moderate Congenital Heart Disease Demonstrate Measurable Neurocognitive Deficits | Melissa L. Perrotta (+6) | 2020 | Journal of the American Heart Association |
| 7300 | Cancer PRSweb: An Online Repository with Polygenic Risk Scores for Major Cancer Traits and Their Evaluation in Two Independent Biobanks | Lars G. Fritsche (+9) | 2020 | American Journal of Human Genetics |
| 9235 | Genome-wide association study identifies 48 common genetic variants associated with handedness | Gabriel Cuellar-Partida (+117) | 2020 | Nature Human Behaviour |
| 9236 | The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank | Judit García-González (+5) | 2020 | Translational Psychiatry |
| 4748 | Effect of Acid Suppressants on the Risk of COVID-19: A Propensity Score-Matched Study Using UK Biobank | Xiude Fan (+7) | 2020 | Gastroenterology |
| 4909 | Genetic Determinants of Antibody-Mediated Immune Responses to Infectious Diseases Agents: A Genome-Wide and HLA Association Study | Guillaume Butler-Laporte (+5) | 2020 | Open Forum Infectious Diseases |
| 5904 | Three pleiotropic loci associated with bone mineral density and lean body mass | Yu-Xue Zhang (+11) | 2020 | Molecular Genetics and Genomics |
| 9234 | Learning patterns of the ageing brain in MRI using deep convolutional networks | Nicola K Dinsdale (+6) | 2020 | NeuroImage |
| 3373 | The mental health of emergency services personnel in the UK Biobank: a comparison with the working population | Sharon A. M. Stevelink (+6) | 2020 | European Journal of Psychotraumatology |
| 4816 | Examination of potential novel biochemical factors in relation to prostate cancer incidence and mortality in UK Biobank | Aurora Perez-Cornago (+8) | 2020 | British Journal of Cancer |
| 4664 | Development and validation of a multivariable risk prediction model for head and neck cancer using the UK Biobank | Caroline Elizabeth McCarthy (+3) | 2020 | International Journal of Oncology |
| 4906 | Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults | Edith Hofer (+98) | 2020 | Nature Communications |
| 5121 | Healthy lifestyle and life expectancy in people with multimorbidity in the UK Biobank: A longitudinal cohort study | Yogini V. Chudasama (+6) | 2020 | PLOS Medicine |
| 5333 | Loci identified by a genome-wide association study of carotid artery stenosis in the eMERGE network | Melody R. Palmer (+24) | 2020 | Genetic Epidemiology |
| 5556 | Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis | Xin-Tong Wei (+12) | 2020 | European Journal of Human Genetics |
| 5581 | Poor Bone Quality is Associated With Greater Arterial Stiffness: Insights From the UK Biobank | Zahra Raisi-Estabragh (+20) | 2020 | Journal of Bone and Mineral Research |
| 5834 | The Duffy-null genotype and risk of infection | Sophie E Legge (+15) | 2020 | Human Molecular Genetics |
| 4091 | Assessing causal relationship from gut microbiota to heel bone mineral density | Jing-Jing Ni (+8) | 2020 | Bone |
| 4605 | Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder | Kevin M. Anderson (+8) | 2020 | Proceedings of the National Academy of Sciences of the United States of America |
| 5315 | Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts | Jie Yuan (+4) | 2020 | PLOS Genetics |
| 7494 | Bayesian sparse heritability analysis with high-dimensional neuroimaging phenotypes | Yize Zhao (+2) | 2020 | Biostatistics |
| 9233 | Generalizability of "GWAS Hits" in Clinical Populations: Lessons from Childhood Cancer Survivors | Cindy Im (+18) | 2020 | American Journal of Human Genetics |
| 4795 | Ethnic Differences in Body Fat Deposition and Liver Fat Content in Two UK-Based Cohorts | Wareed Alenaini (+8) | 2020 | Obesity |
| 9232 | I quit! Is there an association between leaving teaching and improvements in mental health? | John Jerrim (+2) | 2020 | British Educational Research Journal |
| 3603 | Circulating Insulin-like Growth Factor-I Concentrations and Risk of 30 Cancers: Prospective Analyses in UK Biobank | Anika Knuppel (+10) | 2020 | Cancer Research |
| 3611 | Lung Development Genes and Adult Lung Function | Laura Portas (+8) | 2020 | American Journal of Respiratory and Critical Care Medicine |
| 9231 | The reliability and heritability of cortical folds and their genetic correlations across hemispheres | Fabrizio Pizzagalli (+17) | 2020 | Communications Biology |
| 4729 | Does insulin-like growth factor moderate the association between height and risk of cancer at 24 sites? | Solange Parra-Soto (+3) | 2020 | British Journal of Cancer |
| 4881 | Genetic aetiology of blood pressure relates to aortic stiffness with bi-directional causality: evidence from heritability, blood pressure polymorphisms, and Mendelian randomization | Cecelja M et al. | 2020 | Eur Heart J |
| 5173 | Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass | Gui-Juan Feng (+8) | 2020 | Journal of Human Genetics |
| 5823 | The causal effect of obesity on prediabetes and insulin resistance reveals the important role of adipose tissue in insulin resistance | Zong Miao (+15) | 2020 | PLOS Genetics |
| 5885 | The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects | Mark J. Simcoe (+5) | 2020 | Investigative Ophthalmology & Visual Science |
| 9230 | Sleep duration and risk of overall and 22 site-specific cancers: A Mendelian randomization study | Olga E. Titova (+6) | 2020 | International Journal of Cancer |
| 3727 | Associations of BMI and Serum Urate with Developing Dementia: A Prospective Cohort Study | Zhi Cao (+6) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 3863 | A comprehensive genetic and epidemiological association analysis of vitamin D with common diseases/traits in the UK Biobank | Yixuan Ye (+3) | 2020 | Genetic Epidemiology |
| 5394 | Metabolic syndrome biomarkers and prostate cancer risk in the UK Biobank | Maria J. Monroy-Iglesias (+7) | 2020 | International Journal of Cancer |
| 9229 | Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia | Weilai Dong (+48) | 2020 | iScience |
| 3785 | The Genetic Makeup of the Electrocardiogram | Niek Verweij (+8) | 2020 | Cell Systems |
| 5917 | Transcriptomic signatures across human tissues identify functional rare genetic variation | Nicole M. Ferraro (+208) | 2020 | Science |
| 9228 | Looking for Sunshine: Genetic Predisposition to Sun Seeking in 265,000 Individuals of European Ancestry | Marianna Sanna (+9) | 2020 | Journal of Investigative Dermatology |
| 5570 | Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort | Steluta Grama (+12) | 2020 | Translational Psychiatry |
| 5154 | Human genetic determinants of the gut microbiome and their associations with health and disease: a phenome-wide association study | Groot HE et al. | 2020 | Sci Rep |
| 9161 | A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data | Javier de la Fuente (+4) | 2020 | Nature Human Behaviour |
| 9190 | Cerebrovascular risk factors impact frontoparietal network integrity and executive function in healthy ageing | Michele Veldsman (+6) | 2020 | Nature Communications |
| 3368 | Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts | Sara R. Rashkin (+18) | 2020 | Nature Communications |
| 4484 | Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction | Jacqueline Saw (+25) | 2020 | Nature Communications |
| 4751 | Effect of Education on Myopia: Evidence from the United Kingdom ROSLA 1972 Reform | Denis Plotnikov (+6) | 2020 | Investigative Ophthalmology & Visual Science |
| 5236 | Inferring Gene-by-Environment Interactions with a Bayesian Whole-Genome Regression Model | Matthew Kerin (+1) | 2020 | American Journal of Human Genetics |
| 3969 | Accounting for Time: Circadian Rhythms in the Time of COVID-19 | Shaon Sengupta (+3) | 2020 | Journal of Biological Rhythms |
| 4195 | Association of genetic risk for Alzheimer disease and hearing impairment. | Willa D Brenowitz (+8) | 2020 | Neurology |
| 4814 | Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria | Amy K. Dickey (+17) | 2020 | Genetics in Medicine |
| 5107 | H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival | Sayeh Saravi (+9) | 2020 | Journal of Clinical Medicine |
| 2828 | COVID-19 and associations with frailty and multimorbidity: a prospective analysis of UK Biobank participants | Woolford SJ et al. | 2020 | Aging Clin Exp Res |
| 3663 | Sex-specific genetic effects across biomarkers | Emily Flynn (+5) | 2020 | European Journal of Human Genetics |
| 3692 | Increased Risk of Myocardial Infarction Among Patients With Type 2 Diabetes Who Carry the Common rs10830963 Variant in the MTNR1B Gene | Tan X et al. | 2020 | Diabetes Care |
| 4080 | Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank | Lumsden AL et al. | 2020 | EBioMedicine |
| 4235 | Association of Sex Hormones with Risk of Cancers of the Pancreas, Kidney, and Brain in the UK Biobank Cohort Study | Rita Peila (+2) | 2020 | Cancer Epidemiology Biomarkers & Prevention |
| 4531 | Coffee consumption is not associated with risk of multiple sclerosis: A Mendelian randomization study | Lu H et al. | 2020 | Mult Scler Relat Disord |
| 4548 | Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population | Helene Gellert-Kristensen (+5) | 2020 | Hepatology |
| 4968 | Genetically Predicted Blood Pressure Across the Lifespan: Differential Effects of Mean and Pulse Pressure on Stroke Risk | Georgakis MK et al. | 2020 | Hypertension |
| 5004 | Genome-Wide Association Analysis Identified ANXA1 Associated with Shoulder Impingement Syndrome in UK Biobank Samples | Bolun Cheng (+10) | 2020 | G3: Genes, Genomes, Genetics |
| 5289 | Isolated Diastolic Hypertension in the UK Biobank: Comparison of ACC/AHA and ESC/NICE Guideline Definitions | McGrath BP et al. | 2020 | Hypertension |
| 5376 | Mendelian randomization case-control PheWAS in UK Biobank shows evidence of causality for smoking intensity in 28 distinct clinical conditions | King C et al. | 2020 | EClinicalMedicine |
| 5538 | Phenotypic and Molecular Characterization of Risk Loci Associated With Asthma and Lung Function | Karaca M et al. | 2020 | Allergy Asthma Immunol Res |
| 5719 | Sex differences in the association between childhood maltreatment and cardiovascular disease in the UK Biobank | Soares ALG et al. | 2020 | Heart |
| 5772 | Spatial distribution and cognitive impact of cerebrovascular risk-related white matter hyperintensities | Veldsman M et al. | 2020 | Neuroimage Clin |
| 5880 | The Polygenic and Monogenic Basis of Blood Traits and Diseases | Dragana Vuckovic (+112) | 2020 | Cell |
| 9160 | Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations | Ming-Huei Chen (+110) | 2020 | Cell |
| 4765 | Efficient gene-environment interaction tests for large biobank-scale sequencing studies | Xinyu Wang (+8) | 2020 | Genetic Epidemiology |
| 4591 | Compressive Big Data Analytics: An ensemble meta-algorithm for high-dimensional multisource datasets | Simeone Marino (+12) | 2020 | PLOS ONE |
| 5958 | Using a knowledge exchange event to assess study participants' attitudes to research in a rapidly evolving research context | Beange I et al. | 2020 | Wellcome Open Res |
| 6016 | Women's brain aging: Effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer's disease | Ann-Marie G. de Lange (+6) | 2020 | Human Brain Mapping |
| 7634 | Phenome-wide analyses establish a specific association between aortic valve PALMD expression and calcific aortic valve stenosis | Zhonglin Li (+5) | 2020 | Communications Biology |
| 12899 | The NEMP family supports metazoan fertility and nuclear envelope stiffness | Yonit Tsatskis (+30) | 2020 | Science Advances |
| 5684 | Risk of 16 cancers across the full glycemic spectrum: a population-based cohort study using the UK Biobank | Christopher T Rentsch (+8) | 2020 | BMJ Open Diabetes Research & Care |
| 3605 | Health impacts and environmental footprints of diets that meet the Eatwell Guide recommendations: analyses of multiple UK studies | Scheelbeek P et al. | 2020 | BMJ Open |
| 3676 | Vitamin D and COVID-19 infection and mortality in UK Biobank | Claire E. Hastie (+2) | 2020 | European Journal of Nutrition |
| 4338 | Baseline Vitamin D Status, Sleep Patterns, and the Risk of Incident Type 2 Diabetes in Data From the UK Biobank Study | Mengying Wang (+7) | 2020 | Diabetes Care |
| 5015 | Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease | Thomas W. Winkler (+24) | 2020 | BMC Medical Genomics |
| 5270 | Investigating pleiotropic effects of statins on ischemic heart disease in the UK Biobank using Mendelian Randomization | C M Schooling (+3) | 2020 | eLife |
| 7495 | Different scaling of linear models and deep learning in UKBiobank brain images versus machine-learning datasets | Marc-Andre Schulz (+7) | 2020 | Nature Communications |
| 2384 | A population-based phenome-wide association study of cardiac and aortic structure and function | Wenjia Bai (+18) | 2020 | Nature Medicine |
| 5083 | Germline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank | Jun Wei (+10) | 2020 | British Journal of Cancer |
| 4607 | CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses | Xuan Zhou (+2) | 2020 | Nature Communications |
| 5303 | Large-Scale Analyses Provide No Evidence For Gene-Gene Interactions Influencing Type 2 Diabetes Risk | Abhishek Nag (+2) | 2020 | Diabetes |
| 5425 | Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study | Ann-Marie G. de Lange (+12) | 2020 | NeuroImage |
| 5453 | Neuroimaging PheWAS (Phenome-Wide Association Study): A Free Cloud-Computing Platform for Big-Data, Brain-Wide Imaging Association Studies | Lu Zhao (+5) | 2020 | Neuroinformatics |
| 3293 | Automated quantification of myocardial tissue characteristics from native T1 mapping using neural networks with uncertainty-based quality-control | Puyol-Antón E et al. | 2020 | J Cardiovasc Magn Reson |
| 3362 | Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions | Akl C. Fahed (+16) | 2020 | Nature Communications |
| 5380 | Menopausal age and left ventricular remodeling by cardiac magnetic resonance imaging among 14,550 women | Michael C Honigberg (+6) | 2020 | American Heart Journal |
| 5431 | Multimorbidity, polypharmacy, and COVID-19 infection within the UK Biobank cohort | McQueenie R et al. | 2020 | PLoS One |
| 4888 | Genetic and functional insights into the fractal structure of the heart | Hannah V. Meyer (+19) | 2020 | Nature |
| 5095 | Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank | Raisi-Estabragh Z et al. | 2020 | J Public Health (Oxf) |
| 5787 | Supervariants identification for breast cancer | Jianchang Hu (+3) | 2020 | Genetic Epidemiology |
| 6001 | Wearable-device-measured physical activity and future health risk | Tessa Strain (+8) | 2020 | Nature Medicine |
| 7496 | Natural selection contributes to the myopia epidemic | Erping Long (+1) | 2020 | National Science Review |
| 5336 | Long-term antibiotic use during early life and risks to mental traits: an observational study and gene-environment-wide interaction study in UK Biobank cohort | Xiao Liang (+14) | 2020 | Neuropsychopharmacology |
| 3385 | IBDkin: fast estimation of kinship coefficients from identity by descent segments | Zhou Y et al. | 2020 | Bioinformatics |
| 4049 | An Exposure-Wide and Mendelian Randomization Approach to Identifying Modifiable Factors for the Prevention of Depression | Karmel W Choi (+11) | 2020 | American Journal of Psychiatry |
| 4727 | Does Cannabis Intake Protect Against Non-alcoholic Fatty Liver Disease? A Two-Sample Mendelian Randomization Study | Wang X et al. | 2020 | Front Genet |
| 9158 | Multifactorial disorders and polygenic risk scores: predicting common diseases and the possibility of adverse selection in life and protection insurance | Jessye M. Maxwell (+6) | 2020 | Annals of Actuarial Science |
| 3947 | A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care | Seth A. Sharp (+12) | 2020 | Alimentary Pharmacology & Therapeutics |
| 3971 | Accuracy of identifying incident stroke cases from linked health care data in UK Biobank | Rannikmäe K et al. | 2020 | Neurology |
| 4666 | Development and validation of a universal blood donor genotyping platform: a multinational prospective study | Gleadall NS et al. | 2020 | Blood Adv |
| 5975 | Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians | Wang M et al. | 2020 | J Am Coll Cardiol |
| 9157 | Efficient variance components analysis across millions of genomes | Ali Pazokitoroudi (+6) | 2020 | Nature Communications |
| 12900 | Overweight, obesity, and risk of hospitalization for COVID-19: A community-based cohort study of adults in the United Kingdom | Mark Hamer (+3) | 2020 | Proceedings of the National Academy of Sciences of the United States of America |
| 3694 | Polygenic modelling of treatment effect heterogeneity | Zhi Ming Xu (+1) | 2020 | Genetic Epidemiology |
| 4646 | Depressive and anxiety symptomatology among people with asthma or atopic dermatitis: A population-based investigation using the UK Biobank data | S. Hussain (+6) | 2020 | Brain Behavior and Immunity |
| 4825 | Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variations | Roni Rasnic (+2) | 2020 | Scientific Reports |
| 5105 | GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer | Wei Zhou (+55) | 2020 | Nature Communications |
| 5364 | Medical and neurobehavioural phenotypes in male and female carriers of Xp22.31 duplications in the UK Biobank | Samuel J A Gubb (+6) | 2020 | Human Molecular Genetics |
| 9125 | The maternal brain: Region-specific patterns of brain aging are traceable decades after childbirth | Ann-Marie G. de Lange (+6) | 2020 | Human Brain Mapping |
| 9126 | Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer | Pik-Fang Kho (+93) | 2020 | International Journal of Cancer |
| 3462 | Sibling validation of polygenic risk scores and complex trait prediction | Louis Lello (+2) | 2020 | Scientific Reports |
| 5090 | Gluten intake and metabolic health: conflicting findings from the UK Biobank | Inken Behrendt (+2) | 2020 | European Journal of Nutrition |
| 5831 | The Coupon Collection Behavior in Human Reproduction | Erping Long (+1) | 2020 | Current Biology |
| 3285 | Combined Utility of 25 Disease and Risk Factor Polygenic Risk Scores for Stratifying Risk of All-Cause Mortality | Allison Meisner (+10) | 2020 | American Journal of Human Genetics |
| 5342 | Loss-of-Function Myeloperoxidase Mutations Are Associated with Increased Neutrophil Counts and Pustular Skin Disease | Marta Vergnano (+43) | 2020 | American Journal of Human Genetics |
| 3396 | Evaluating the impact of AMPK activation, a target of metformin, on risk of cardiovascular diseases and cancer in the UK Biobank: a Mendelian randomisation study | Shan Luo (+3) | 2020 | Diabetologia |
| 5889 | The role of overweight in the association between the Mediterranean diet and the risk of type 2 diabetes mellitus: a mediation analysis among 21 585 UK biobank participants | Perrine André (+9) | 2020 | International Journal of Epidemiology |
| 7497 | The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation | Robert G. Mealer (+14) | 2020 | Scientific Reports |
| 3439 | The association between recreational screen time and cancer risk: findings from the UK Biobank, a large prospective cohort study | Ruth F. Hunter (+2) | 2020 | International Journal of Behavioral Nutrition and Physical Activity |
| 3280 | Chances and challenges of machine learning-based disease classification in genetic association studies illustrated on age-related macular degeneration | Felix Guenther (+6) | 2020 | Genetic Epidemiology |
| 4960 | Genetically determined intelligence and coronary artery disease risk | Ling Li (+4) | 2020 | Clinical Research in Cardiology |
| 2343 | Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis | Parisinos CA et al. | 2020 | J Hepatol |
| 3267 | Serum uric acid levels and risk of kidney cancer incidence and mortality: A prospective cohort study | Dai XY et al. | 2020 | Cancer Med |
| 4175 | Association of asthma and its genetic predisposition with the risk of severe COVID-19 | Zhu Z et al. | 2020 | J Allergy Clin Immunol |
| 4458 | Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping | Liu Z et al. | 2020 | J Hepatol |
| 4526 | Caffeinated Coffee and Tea Consumption,Genetic Variation and Cognitive Function in the UK Biobank | Marilyn C Cornelis (+2) | 2020 | Journal of Nutrition |
| 4557 | Common gene variants in ASGR1 gene locus associate with reduced cardiovascular risk in absence of pleiotropic effects | Ali L et al. | 2020 | Atherosclerosis |
| 4756 | Effects of body mass index on relationship status, social contact and socio-economic position: Mendelian randomization and within-sibling study in UK Biobank | Howe LD et al. | 2020 | Int J Epidemiol |
| 4796 | Ethnic disparities in hospitalisation for COVID-19 in England: The role of socioeconomic factors, mental health, and inflammatory and pro-inflammatory factors in a community-based cohort study | Lassale C et al. | 2020 | Brain Behav Immun |
| 4835 | Exploring Phenotypic and Genetic Overlap Between Cannabis Use and Schizotypy | James Vaissiere (+4) | 2020 | Twin Research and Human Genetics |
| 4845 | Factorial Mendelian randomization: using genetic variants to assess interactions | Rees JMB et al. | 2020 | Int J Epidemiol |
| 4899 | Genetic Basis and Prognostic Value of Exercise QT Dynamics | van Duijvenboden S et al. | 2020 | Circ Genom Precis Med |
| 5018 | Genome-Wide Association of Kidney Traits in Hispanics/Latinos Using Dense Imputed Whole-Genome Sequencing Data: The Hispanic Community Health Study/Study of Latinos | Qian H et al. | 2020 | Circ Genom Precis Med |
| 5114 | Hematologic Markers and Prostate Cancer Risk: A Prospective Analysis in UK Biobank | Eleanor L Watts (+5) | 2020 | Cancer Epidemiology Biomarkers & Prevention |
| 5296 | Kidney Disease Biomarkers Improve Heart Failure Risk Prediction in the General Population | Nowak C et al. | 2020 | Circ Heart Fail |
| 5332 | Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers | Schneider CV et al. | 2020 | Gastroenterology |
| 5384 | Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction | Choquet H et al. | 2020 | Circ Genom Precis Med |
| 5814 | The associations between loneliness, social exclusion and pain in the general population: A N=502,528 cross-sectional UK Biobank study | Sarah F Allen (+3) | 2020 | Journal of Psychiatric Research |
| 5819 | The Barriers and Motivators to Using Human Tissues for Research: The Views of UK-Based Biomedical Researchers | Lawrence E et al. | 2020 | Biopreserv Biobank |
| 5884 | The reported impact of public involvement in biobanks: A scoping review | Luna Puerta L et al. | 2020 | Health Expect |
| 5926 | Twenty-year sociodemographic trends in lung cancer in non-smokers: A UK-based cohort study of 3.7 million people | Rait G et al. | 2020 | Cancer Epidemiol |
| 3673 | Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations | Ying Wang (+5) | 2020 | Nature Communications |
| 3687 | Association between childhood maltreatment and the prevalence and complexity of multimorbidity: A cross-sectional analysis of 157,357 UK Biobank participants | Hanlon P et al. | 2020 | J Comorb |
| 5800 | Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies | Zhongshang Yuan (+7) | 2020 | Nature Communications |
| 3552 | Association of obesity status and metabolic syndrome with site-specific cancers: a population-based cohort study | Zhi Cao (+6) | 2020 | British Journal of Cancer |
| 5235 | Inferring disease subtypes from clusters in explanation space | Marc-Andre Schulz (+4) | 2020 | Scientific Reports |
| 7498 | Statistical properties of sketching algorithms | D. C. Ahfock (+2) | 2020 | Biometrika |
| 7499 | Machine learning prediction of susceptibility to visceral fat associated diseases | M. Aldraimli (+6) | 2020 | Health and Technology |
| 3266 | Metabolic syndrome and risk of pancreatic cancer: A population-based prospective cohort study | Bin Xia (+11) | 2020 | International Journal of Cancer |
| 3615 | Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia | David Curtis | 2020 | Molecular Genetics and Metabolism |
| 4667 | Development and validation of risk prediction models for multiple cardiovascular diseases and Type 2 diabetes | Mehrdad Rezaee (+4) | 2020 | PLOS ONE |
| 4733 | Does the association between physical capability and mortality differ by deprivation? Findings from the UK Biobank population-based cohort study | Juan Pablo Rey-Lopez (+8) | 2020 | Journal of Sports Sciences |
| 5622 | Psychiatric comorbid disorders of cognition: a machine learning approach using 1175 UK Biobank participants | Chenlu Li (+3) | 2020 | BMJ Mental Health |
| 5677 | Retinal Vascular Tortuosity and Diameter Associations with Adiposity and Components of Body Composition | Robyn J. Tapp (+8) | 2020 | Obesity |
| 4861 | Four pleiotropic loci associated with fat mass and lean mass | Yu Liu (+14) | 2020 | International Journal of Obesity |
| 5244 | Insulin-like growth factor-1 and site-specific cancers: A Mendelian randomization study | Susanna C. Larsson (+5) | 2020 | Cancer Medicine |
| 7635 | Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic etiology of ocular diseases | Mark J Simcoe (+4) | 2020 | Human Molecular Genetics |
| 9123 | Isolated Diastolic Hypertension in the UK Biobank | Brian P. McGrath (+6) | 2020 | Hypertension |
| 3450 | Do neighbourhood characteristics act together to influence BMI? A cross-sectional study of urban parks and takeaway/fast-food stores as modifiers of the effect of physical activity facilities | Kate E Mason (+2) | 2020 | Social Science & Medicine |
| 4801 | Evaluating shared genetic influences on nonsyndromic cleft lip/palate and oropharyngeal neoplasms | Laurence J. Howe (+10) | 2020 | Genetic Epidemiology |
| 9156 | Tutorial: a guide to performing polygenic risk score analyses | Shing Wan Choi (+2) | 2020 | Nature Protocols |
| 4700 | Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2 | Yasmmyn D Salinas (+2) | 2020 | American Journal of Epidemiology |
| 5945 | Understanding How Much TV is Too Much A Nonlinear Analysis of the Association Between Television Viewing Time and Adverse Health Outcomes | Hamish M E Foster (+7) | 2020 | Mayo Clinic Proceedings |
| 5816 | The associations between thermal variety and health: Implications for space heating energy use | Harry R. Kennard (+3) | 2020 | PLOS ONE |
| 5989 | Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort | Andrea L. Darling (+3) | 2020 | British Journal Of Nutrition |
| 9155 | All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes | Alice E. Hughes (+9) | 2020 | Wellcome Open Research |
| 3458 | A genetic model of ivabradine recapitulates results from randomized clinical trials | Legault MA et al. | 2020 | PLoS One |
| 3461 | Genetic architecture of complex traits and disease risk predictors | Soke Yuen Yong (+3) | 2020 | Scientific Reports |
| 4858 | Fine-scale population structure in the UK Biobank: implications for genome-wide association studies | James P Cook (+2) | 2020 | Human Molecular Genetics |
| 4946 | Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease | Helgadottir A et al. | 2020 | Eur Heart J |
| 7500 | Mendelian randomization supports a causative effect of TSH on thyroid carcinoma | Jonathan M Fussey (+5) | 2020 | Endocrine Related Cancer |
| 3584 | A unified framework for association and prediction from vertex-wise grey-matter structure | Baptiste Couvy-Duchesne (+11) | 2020 | Human Brain Mapping |
| 5593 | Prediction of colorectal cancer risk based on profiling with common genetic variants | Xue Li (+12) | 2020 | International Journal of Cancer |
| 5598 | Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort | Janice L Atkins (+6) | 2020 | The Journals of Gerontology Series A |
| 9154 | Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans | Siyuan Liu (+4) | 2020 | Proceedings of the National Academy of Sciences of the United States of America |
| 4901 | Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression | Saskia P. Hagenaars (+47) | 2020 | American Journal of Medical Genetics Part B Neuropsychiatric Genetics |
| 3438 | Physical activity and cancer risk: Findings from the UK Biobank, a large prospective cohort study | Jennifer M. Murray (+2) | 2020 | Cancer Epidemiology |
| 4622 | Cross-sectional associations between central and general adiposity with albuminuria: observations from 400,000 people in UK Biobank | Pengfei Zhu (+9) | 2020 | International Journal of Obesity |
| 5900 | The undiagnosed disease burden associated with alpha-1 antitrypsin deficiency genotypes | Tomoko Nakanishi (+7) | 2020 | European Respiratory Journal |
| 4384 | Body mass index and the risk of COVID-19 across ethnic groups: Analysis of UK Biobank | Cameron Razieh (+4) | 2020 | Diabetes Obesity and Metabolism |
| 5883 | The relationship of parental longevity with the aging brain - results from UK Biobank | Qu Tian (+4) | 2020 | GeroScience |
| 4336 | Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses | Ben Brumpton (+32) | 2020 | Nature Communications |
| 5628 | PWAS: proteome-wide association study - linking genes and phenotypes by functional variation in proteins | Nadav Brandes (+2) | 2020 | Genome Biology |
| 5947 | Understanding the genetic determinants of the brain with MOSTest | Dennis van der Meer (+11) | 2020 | Nature Communications |
| 9153 | Renin-Angiotensin-Aldosterone System Blockers Are Not Associated With Coronavirus Disease 2019 (COVID-19) Hospitalization: Study of 1,439 UK Biobank Cases | Zahra Raisi-Estabragh (+7) | 2020 | Frontiers in Cardiovascular Medicine |
| 3375 | Genetic variants associated with rotator cuff tearing utilizing multiple population-based genetic resources | Robert Z Tashjian (+4) | 2020 | Journal of Shoulder and Elbow Surgery |
| 5474 | Normalized Indices Derived from Visceral Adipose Mass Assessed by Magnetic Resonance Imaging and Their Correlation with Markers for Insulin Resistance and Prediabetes | Jürgen Machann (+10) | 2020 | Nutrients |
| 3434 | Diabetes, Glycated Hemoglobin, and the Risk of Myocardial Infarction in Women and Men: A Prospective Cohort Study of the UK Biobank | Marit de Jong (+2) | 2020 | Diabetes Care |
| 5555 | Platelet Measurements and Type 2 Diabetes: Investigations in Two Population-Based Cohorts | Benjamin A. T. Rodriguez (+1) | 2020 | Frontiers in Cardiovascular Medicine |
| 4800 | Evaluating polygenic risk scores in assessing risk of nine solid and hematologic cancers in European descendants | Jungyoon Choi (+4) | 2020 | International Journal of Cancer |
| 9152 | Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance | Rene C. Adam (+15) | 2020 | Journal of Lipid Research |
| 3620 | Impact of Genetically Predicted Red Blood Cell Traits on Venous Thromboembolism: Multivariable Mendelian Randomization Study Using UK Biobank | Shan Luo (+4) | 2020 | Journal of the American Heart Association |
| 2462 | Depression with atypical neurovegetative symptoms shares genetic predisposition with immuno-metabolic traits and alcohol consumption | Badini I et al. | 2020 | Psychol Med |
| 3891 | A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine | Yanjun Guo (+5) | 2020 | Nature Communications |
| 4782 | Estimated 24-Hour Urinary Sodium Excretion and Incident Cardiovascular Disease and Mortality Among 398 628 Individuals in UK Biobank | Paul Elliott (+7) | 2020 | Hypertension |
| 5326 | Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits | Andrew D. Bretherick (+18) | 2020 | PLOS Genetics |
| 9127 | Genetically Predicted Blood Pressure Across the Lifespan | Marios K. Georgakis (+5) | 2020 | Hypertension |
| 4357 | Biomarkers Profile of People With Sarcopenia: A Cross-sectional Analysis From UK Biobank | Fanny Petermann-Rocha (+4) | 2020 | Journal of the American Medical Directors Association |
| 3736 | Vitamin D Status and Risk of All-Cause and Cause-Specific Mortality in a Large Cohort: Results From the UK Biobank | Xikang Fan (+8) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 4975 | Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis | Dipender Gill (+6) | 2020 | Journal of the American Heart Association |
| 9124 | Neuroharmony: A new tool for harmonizing volumetric MRI data from unseen scanners | Rafael Garcia-Dias (+34) | 2020 | NeuroImage |
| 4693 | Differences in directed functional brain connectivity related to age, sex and mental health | Martina J. Lund (+6) | 2020 | Human Brain Mapping |
| 5650 | Recent Caffeine Drinking Associates with Cognitive Function in the UK Biobank | Marilyn C. Cornelis (+2) | 2020 | Nutrients |
| 2484 | Longitudinal Changes in Fat Mass and the Hippocampus | Ambikairajah A et al. | 2020 | Obesity (Silver Spring) |
| 3895 | A genome-wide scan for pleiotropy between bone mineral density and nonbone phenotypes | Maria A. Christou (+8) | 2020 | Bone Research |
| 4259 | Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study | Wells PM et al. | 2020 | Lancet Rheumatol |
| 4372 | BMI and Cause-Specific Hospital Admissions and Costs: The UK Biobank Cohort Study | O'Halloran R et al. | 2020 | Obesity (Silver Spring) |
| 4486 | Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts | Moll M et al. | 2020 | Lancet Respir Med |
| 4562 | Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities | Armstrong NJ et al. | 2020 | Stroke |
| 4670 | Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study | Forgetta V et al. | 2020 | PLoS Med |
| 4722 | Do Serum Urate-Associated Genetic Variants Differentially Contribute to Gout Risk According to Body Mass Index? Analysis of the UK Biobank | Tai V et al. | 2020 | Arthritis Rheumatol |
| 4966 | Genetically Elevated LDL Associates with Lower Risk of Intracerebral Hemorrhage | Falcone GJ et al. | 2020 | Ann Neurol |
| 5130 | Heritability of pubertal timing: detailed evaluation of specific milestones in healthy boys and girls | Busch AS et al. | 2020 | Eur J Endocrinol |
| 5176 | Identification of susceptibility variants to benign childhood epilepsy with centro-temporal spikes (BECTS) in Chinese Han population | Shi XY et al. | 2020 | EBioMedicine |
| 5287 | Is There a Link between Different Types of Alcoholic Drinks and Obesity? An Analysis of 280,183 UK Biobank Participants | Elif Inan-Eroglu (+5) | 2020 | International Journal of Environmental Research and Public Health |
| 5349 | Lung function changes over 8 years and testosterone markers in both sexes: UK Biobank | Alexandra Lenoir (+5) | 2020 | ERJ Open Research |
| 5553 | Plasma phospholipid fatty acids, bone mineral density and fracture risk: Evidence from a Mendelian randomization study | Yuan S et al. | 2020 | Clin Nutr |
| 5762 | Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants | Larsson SC et al. | 2020 | PLoS Med |
| 5779 | Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures | Harris MA et al. | 2020 | Psychol Med |
| 5890 | The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population | Chami N et al. | 2020 | PLoS Med |
| 5998 | Walking pace improves all-cause and cardiovascular mortality risk prediction: A UK Biobank prognostic study | Argyridou S et al. | 2020 | Eur J Prev Cardiol |
| 6014 | Whole-genome sequencing of patients with rare diseases in a national health system | Turro E et al. | 2020 | Nature |
| 8198 | Evaluation of the Suitability of an Existing Job-Exposure Matrix for the Assessment of Exposure of UK Biobank Participants to Dust, Fumes, and Diesel Exhaust Particulates | Eirini Dimakakou (+3) | 2020 | International Journal of Environmental Research and Public Health |
| 9121 | Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction | Angel C Y Mak (+34) | 2020 | Genetics |
| 9122 | Genetic susceptibility, plant-based dietary patterns, and risk of cardiovascular disease | Yoriko Heianza (+5) | 2020 | American Journal of Clinical Nutrition |
| 3377 | BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: Preliminary findings from UK biobank | Sattar N et al. | 2020 | Diabetes Metab Syndr |
| 4014 | Age-of-onset information helps identify 76 genetic variants associated with allergic disease | Manuel A. R. Ferreira (+39) | 2020 | PLOS Genetics |
| 5216 | Improving the Generalizability of Convolutional Neural Network-Based Segmentation on CMR Images | Chen Chen (+16) | 2020 | Frontiers in Cardiovascular Medicine |
| 5137 | High-definition likelihood inference of genetic correlations across human complex traits | Zheng Ning (+2) | 2020 | Nature Genetics |
| 5574 | Polygenic risk scores allow risk stratification for keratinocyte cancer in organ transplant recipients. | Mathias Seviiri (+7) | 2020 | Journal of Investigative Dermatology |
| 4916 | Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study | Harry D Green (+11) | 2020 | International Journal of Epidemiology |
| 3208 | Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions | Yakov A. Tsepilov (+9) | 2020 | Communications Biology |
| 3869 | A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank | Wenjian Bi (+4) | 2020 | American Journal of Human Genetics |
| 3095 | Monogenic and polygenic inheritance become instruments for clonal selection | Po-Ru Loh (+2) | 2020 | Nature |
| 4483 | Chromosomal alterations among age-related haematopoietic clones in Japan | Chikashi Terao (+11) | 2020 | Nature |
| 4773 | Elevated body mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study | Butler-Laporte G et al. | 2020 | Clin Microbiol Infect |
| 4860 | FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease | Saedis Saevarsdottir (+45) | 2020 | Nature |
| 5300 | Large Copy-Number Variants in UK Biobank Caused by Clonal Hematopoiesis May Confound Penetrance Estimates | Marcus Tuke (+8) | 2020 | American Journal of Human Genetics |
| 5997 | Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study | Brandon S. Klinedinst (+15) | 2020 | Obesity |
| 3583 | Glycated Hemoglobin A1c, Lung Function, and Hospitalizations Among Adults with Asthma | Yang G et al. | 2020 | J Allergy Clin Immunol Pract |
| 2922 | Automated classification of depression from structural brain measures across two independent community-based cohorts | Aleks Stolicyn (+12) | 2020 | Human Brain Mapping |
| 4741 | Dynamic linkage of COVID-19 test results between Public Health England's Second Generation Surveillance System and UK Biobank | Jacob Armstrong (+6) | 2020 | Microbial Genomics |
| 5188 | Imaging genomics discovery of a new risk variant for Alzheimer's disease in the postsynaptic SHARPIN gene | Sourena Soheili-Nezhad (+9) | 2020 | Human Brain Mapping |
| 4768 | Efficient polygenic risk scores for biobank scale data by exploiting phenotypes from inferred relatives | Buu Truong (+6) | 2020 | Nature Communications |
| 4882 | Genetic aetiology of self-harm ideation and behaviour | Adrian I. Campos (+10) | 2020 | Scientific Reports |
| 5243 | Insomnia, Anxiety and Depression in Adult Cochlear Implant Users With Tinnitus | Pierzycki RH et al. | 2020 | Ear Hear |
| 5690 | Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study | André F. S. Amaral (+14) | 2020 | BMC Pulmonary Medicine |
| 4794 | Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits | Wei Cheng (+2) | 2020 | PLOS Genetics |
| 5844 | The effects of age at menarche and first sexual intercourse on reproductive and behavioural outcomes: A Mendelian randomization study | Rebecca B. Lawn (+7) | 2020 | PLOS ONE |
| 3722 | Child maltreatment and cardiovascular disease: quantifying mediation pathways using UK Biobank | Frederick K. Ho (+8) | 2020 | BMC Medicine |
| 7301 | Population-Specific Recombination Maps from Segments of Identity by Descent | Ying Zhou (+2) | 2020 | American Journal of Human Genetics |
| 7501 | Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs | Nathan R. Treff (+7) | 2020 | Genes |
| 4730 | Does meeting physical activity recommendations ameliorate association between television viewing with cardiovascular disease risk? A cross-sectional, population-based analysis | Freda Patterson (+5) | 2020 | BMJ Open |
| 3686 | Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking | Ahmed A. Z. Dawoud (+2) | 2020 | Leukemia |
| 4319 | Atherosclerotic Aortic Calcification-Associated Polymorphism in HDAC9 and Associations with Mortality, Cardiovascular Disease, and Kidney Disease | Johan Ärnlöv (+2) | 2020 | iScience |
| 5965 | Using major depression polygenic risk scores to explore the depressive symptom continuum | Bradley S. Jermy (+7) | 2020 | Psychological Medicine |
| 3846 | ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants | Chia-Ling Kuo (+4) | 2020 | Aging |
| 3925 | A Polygenic Risk Score as a Risk Factor for Medication-Associated Fractures | Despoina Manousaki (+8) | 2020 | Journal of Bone and Mineral Research |
| 5584 | Population variability in social brain morphology for social support, household size and friendship satisfaction | Arezoo Taebi (+5) | 2020 | Social Cognitive and Affective Neuroscience |
| 9120 | Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk | Kevin M. Anderson (+5) | 2020 | Nature Communications |
| 5428 | Multimorbidity and SARS-CoV-2 infection in UK Biobank | Yogini V Chudasama (+7) | 2020 | Diabetes & Metabolic Syndrome Clinical Research & Reviews |
| 5891 | The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank | Jie V. Zhao (+1) | 2020 | BMC Medicine |
| 5537 | Phenotypic and Genetic Characterization of Lower LDL Cholesterol and Increased Type 2 Diabetes Risk in the UK Biobank | Yann C. Klimentidis (+6) | 2020 | Diabetes |
| 5780 | Structural Brain Architectures Match Intrinsic Functional Networks and Vary across Domains: A Study from 15 000+ Individuals | Na Luo (+15) | 2020 | Cerebral Cortex |
| 3249 | Ascertainment Bias in the Association Between Elevated Lipoprotein(a) and Familial Hypercholesterolemia | Trinder M et al. | 2020 | J Am Coll Cardiol |
| 4596 | Confound modelling in UK Biobank brain imaging | Fidel Alfaro-Almagro (+7) | 2020 | NeuroImage |
| 5330 | Lipoprotein(a) in Alzheimer, Atherosclerotic, Cerebrovascular, Thrombotic, and Valvular Disease: Mendelian Randomization Investigation | Larsson SC et al. | 2020 | Circulation |
| 5631 | Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area | Dennis van der Meer (+10) | 2020 | Cerebral Cortex |
| 5861 | The Human Leukocyte Antigen Locus and Rheumatic Heart Disease Susceptibility in South Asians and Europeans | Kathryn Auckland (+10) | 2020 | Scientific Reports |
| 9119 | Fine-tuning of Genome-Wide Polygenic Risk Scores and Prediction of Gestational Diabetes in South Asian Women | Amel Lamri (+5) | 2020 | Scientific Reports |
| 3283 | Network Efficiency Mediates the Relationship Between Vascular Burden and Cognitive Impairment: A Diffusion Tensor Imaging Study in UK Biobank | Shen J et al. | 2020 | Stroke |
| 3643 | External Validation of Risk Prediction Models Incorporating Common Genetic Variants for Incident Colorectal Cancer Using UK Biobank | Catherine L. Saunders (+10) | 2020 | Cancer Prevention Research |
| 3683 | Diabetes, Glycated Hemoglobin, and Risk of Cancer in the UK Biobank Study | Rita Peila (+1) | 2020 | Cancer Epidemiology Biomarkers & Prevention |
| 3950 | A Systematic Analysis of Interactions between Environmental Risk Factors and Genetic Variation in Susceptibility to Colorectal Cancer | Tian Yang (+6) | 2020 | Cancer Epidemiology Biomarkers & Prevention |
| 4023 | Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study | Larsson SC et al. | 2020 | Circ Genom Precis Med |
| 4145 | Association between herpes simplex virus 1 exposure and the risk of depression in UK Biobank | Ye J et al. | 2020 | Clin Transl Med |
| 4212 | Association of Myopia and Intraocular Pressure With Retinal Detachment in European Descent Participants of the UK Biobank Cohort: A Mendelian Randomization Study | Han X et al. | 2020 | JAMA Ophthalmol |
| 4253 | Associations Between Depression, Arterial Stiffness, and Metabolic Syndrome Among Adults in the UK Biobank Population Study: A Mediation Analysis | Dregan A et al. | 2020 | JAMA Psychiatry |
| 4534 | Cognitive Deficit and White Matter Changes in Persons With Celiac Disease: A Population-Based Study | Croall ID et al. | 2020 | Gastroenterology |
| 4625 | Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache | Siewert KM et al. | 2020 | Int J Epidemiol |
| 4657 | Detecting Shared Genetic Architecture Among Multiple Phenotypes by Hierarchical Clustering of Gene-Level Association Statistics | Melissa R McGuirl (+3) | 2020 | Genetics |
| 4806 | Evaluating the Utility of Polygenic Risk Scores in Identifying High-Risk Individuals for Eight Common Cancers | Jia G et al. | 2020 | JNCI Cancer Spectr |
| 5290 | Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity | Benjamin B Chu (+7) | 2020 | GigaScience |
| 5722 | Sex differences in the association of photoperiod with hippocampal subfield volumes in older adults: A cross-sectional study in the UK Biobank cohort | Majrashi NA et al. | 2020 | Brain Behav |
| 5782 | Studying individual risk factors for self-harm in the UK Biobank: A polygenic scoring and Mendelian randomisation study | Lim KX et al. | 2020 | PLoS Med |
| 5920 | Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease | Matsunaga H et al. | 2020 | Circ Genom Precis Med |
| 6010 | Whole-exome sequencing and genome-wide association studies identify novel sarcopenia risk genes in Han Chinese | Shu Ran (+12) | 2020 | Molecular Genetics & Genomic Medicine |
| 9118 | Variants associated with HHIP expression have sex-differential effects on lung function | Katherine A. Fawcett (+74) | 2020 | Wellcome Open Research |
| 4255 | Associations between diet and handgrip strength: a cross-sectional study from UK Biobank | A. Gedmantaite (+5) | 2020 | Mechanisms of Ageing and Development |
| 7293 | Trait Insights Gained by Comparing Genome-Wide Association Study Results using Different Chronic Obstructive Pulmonary Disease Definitions. | Jaehyun Joo (+3) | 2020 | AMIA Joint Summits on Translational Science Proceedings |
| 2817 | Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank | Claire L. Niedzwiedz (+11) | 2020 | BMC Medicine |
| 4010 | Age, sex and disease-specific associations between resting heart rate and cardiovascular mortality in the UK BIOBANK | Raisi-Estabragh Z et al. | 2020 | PLoS One |
| 4146 | Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study | Travis J. Meyers (+11) | 2020 | International Journal of Cancer |
| 5699 | Scalable probabilistic PCA for large-scale genetic variation data | Aman Agrawal (+4) | 2020 | PLOS Genetics |
| 5486 | Obesity and risk of COVID-19: analysis of UK biobank | Thomas Yates (+4) | 2020 | Primary Care Diabetes |
| 7302 | Non-parametric Polygenic Risk Prediction via Partitioned GWAS Summary Statistics | Sung Chun (+7) | 2020 | American Journal of Human Genetics |
| 7597 | Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases | Juan R González (+12) | 2020 | American Journal of Human Genetics |
| 9116 | Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study | Abigail Emma Russell (+9) | 2020 | Brain Behavior and Immunity |
| 9117 | Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome | Yu-Han H. Hsu (+12) | 2020 | International Journal of Obesity |
| 5838 | The effect of LRRK2 loss-of-function variants in humans | Nicola Whiffin (+36) | 2020 | Nature Medicine |
| 4076 | APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort | Chia-Ling Kuo (+6) | 2020 | The Journals of Gerontology Series A |
| 4734 | Does type 2 diabetes increase the risk of musculoskeletal pain? Cross-sectional and longitudinal analyses of UK biobank data | Ana Paula Carvalho-E-Silva (+3) | 2020 | Seminars in Arthritis and Rheumatism |
| 4940 | Genetic stratification of depression in UK Biobank | David M. Howard (+15) | 2020 | Translational Psychiatry |
| 5323 | Lifestyle risk factors, inflammatory mechanisms, and COVID-19 hospitalization: A community-based cohort study of 387,109 adults in UK | Mark Hamer (+3) | 2020 | Brain Behavior and Immunity |
| 5604 | Prevalence and demographics of multiple sclerosis-associated uveitis: a UK biobank study | Thomas Rp Taylor (+4) | 2020 | Multiple Sclerosis and Related Disorders |
| 9115 | Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data | Huwenbo Shi (+8) | 2020 | American Journal of Human Genetics |
| 2963 | Enhancer Locus in ch14q23.1 Modulates Brain Asymmetric Temporal Regions Involved in Language Processing | Yann Le Guen (+6) | 2020 | Cerebral Cortex |
| 3888 | A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior | Jacquelyn L. Meyers (+24) | 2020 | Molecular Psychiatry |
| 5922 | Transthyretin-stabilising mutation T119M is not associated with protection against vascular disease or death in the UK Biobank | Margaret M. Parker (+7) | 2020 | Amyloid |
| 3108 | Quantifying genetic effects on disease mediated by assayed gene expression levels | Douglas W. Yao (+3) | 2020 | Nature Genetics |
| 5698 | Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts | Wei Zhou (+13) | 2020 | Nature Genetics |
| 5724 | Sex hormone-binding globulin and arthritis: a Mendelian randomization study | Zihao Qu (+5) | 2020 | Arthritis Research & Therapy |
| 9114 | Early exposure to social disadvantages and later life body mass index beyond genetic predisposition in three generations of Finnish birth cohorts | Estelle Lowry (+12) | 2020 | BMC Public Health |
| 4769 | Efficient toolkit implementing best practices for principal component analysis of population genetic data | Florian Privé (+4) | 2020 | Bioinformatics |
| 5731 | Sex-specific associations of insulin resistance with chronic kidney disease and kidney function: a bi-directional Mendelian randomisation study | Jie V. Zhao (+1) | 2020 | Diabetologia |
| 9113 | Characterizing the Causal Pathway for Genetic Variants Associated with Neurological Phenotypes Using Human Brain-Derived Proteome Data | Nelson K. Kibinge (+3) | 2020 | American Journal of Human Genetics |
| 12901 | Genome-wide association study of the sensitivity to environmental stress and adversity neuroticism cluster | M Nagel (+3) | 2020 | Acta Psychiatrica Scandinavica |
| 3079 | XTRACT - Standardised protocols for automated tractography in the human and macaque brain | Shaun Warrington (+8) | 2020 | NeuroImage |
| 3864 | A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank | Beate Leppert (+7) | 2020 | PLOS Genetics |
| 3866 | A Data-Driven Review of the Genetic Factors of Pregnancy Complications | Yury A. Barbitoff (+6) | 2020 | International Journal of Molecular Sciences |
| 4038 | Ambient Air Pollution Associations with Retinal Morphology in the UK Biobank | Chua SYL et al. | 2020 | Invest Ophthalmol Vis Sci |
| 4731 | Does Obesity Cause Thyroid Cancer? A Mendelian Randomization Study | Jonathan Mark Fussey (+5) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 9111 | Network Efficiency Mediates the Relationship Between Vascular Burden and Cognitive Impairment | Jun Shen (+3) | 2020 | Stroke |
| 9112 | Genomic analysis of diet composition finds novel loci and associations with health and lifestyle | S. Fleur W. Meddens (+42) | 2020 | Molecular Psychiatry |
| 3921 | A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank | Xueyi Shen (+7) | 2020 | Nature Communications |
| 4715 | Diurnal Preference and Grey Matter Volume in a Large Population of Older Adults: Data from the UK Biobank | Ray Norbury | 2020 | Journal of Circadian Rhythms |
| 2909 | Body size, body composition and endometrial cancer risk among postmenopausal women in UK Biobank | Wemimo Omiyale (+2) | 2020 | International Journal of Cancer |
| 3455 | Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy | James P. Pirruccello (+18) | 2020 | Nature Communications |
| 3675 | Vitamin D concentrations and COVID-19 infection in UK Biobank | Claire E Hastie (+13) | 2020 | Diabetes & Metabolic Syndrome Clinical Research & Reviews |
| 4007 | Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts | Ahmed Ehakeem (+3) | 2020 | Annals of Human Biology |
| 4559 | Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval | Julia Ramírez (+6) | 2020 | American Journal of Human Genetics |
| 4819 | Exogenous hormone use, reproductive factors and risk of intrahepatic cholangiocarcinoma among women: results from cohort studies in the Liver Cancer Pooling Project and the UK Biobank | Jessica L. Petrick (+37) | 2020 | British Journal of Cancer |
| 5182 | Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes | Afrah Shafquat (+2) | 2020 | BMC Bioinformatics |
| 5430 | Multimorbidity, mortality, and HbA1c in type 2 diabetes: A cohort study with UK and Taiwanese cohorts | Jason I. Chiang (+10) | 2020 | PLOS Medicine |
| 5497 | Occupational exposure to inhaled pollutants and risk of airflow obstruction: a large UK population-based UK Biobank cohort | Steven S Sadhra (+8) | 2020 | Thorax |
| 5955 | Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study | Tom G Richardson (+4) | 2020 | The BMJ |
| 5551 | Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: A prospective study from UK Biobank | Fanny Petermann-Rocha (+9) | 2020 | Maturitas |
| 5646 | Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma | Yosuke Tanigawa (+13) | 2020 | PLOS Genetics |
| 5957 | Use of proton pump inhibitors and histamine-2 receptor antagonists and risk of gastric cancer in two population-based studies | Peipei Liu (+7) | 2020 | British Journal of Cancer |
| 7502 | Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models | Sahir R. Bhatnagar (+7) | 2020 | PLOS Genetics |
| 12902 | Clinical Features and Genetic Risk of Demyelination Following Anti-TNF Treatment | Simeng Lin (+26) | 2020 | Journal of Crohn's and Colitis |
| 5634 | Race, Socioeconomic Deprivation, and Hospitalization for COVID-19 in English participants of a National Biobank | Patel AP et al. | 2020 | medRxiv |
| 3695 | Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants | Elodie Persyn (+5) | 2020 | Nature Communications |
| 3804 | Interactions between season of birth, chronological age and genetic polymorphisms in determining later-life chronotype | Altug Didikoglu (+4) | 2020 | Mechanisms of Ageing and Development |
| 3942 | A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank | Oh ES et al. | 2020 | Alzheimers Dement |
| 4168 | Association Between Walking Pace and Stroke Incidence: Findings From the UK Biobank Prospective Cohort Study | Hayes S et al. | 2020 | Stroke |
| 4528 | Coffee Consumption and Kidney Function: A Mendelian Randomization Study | Kennedy OJ et al. | 2020 | Am J Kidney Dis |
| 4628 | Deciphering Sex-Specific Genetic Architectures Using Local Bayesian Regressions | Scott A Funkhouser (+4) | 2020 | Genetics |
| 5245 | Insulin-like growth factor-1, insulin-like growth factor-binding protein-3, and breast cancer risk: observational and Mendelian randomization analyses with ∼430 000 women | Murphy N et al. | 2020 | Ann Oncol |
| 5740 | Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study | Bahrami S et al. | 2020 | JAMA Psychiatry |
| 3138 | Age-dependent effect of APOE and polygenic component on Alzheimer's disease | Eftychia Bellou (+8) | 2020 | Neurobiology of Aging |
| 5288 | Is Type 2 Diabetes Causally Associated With Cancer Risk? Evidence From a Two-Sample Mendelian Randomization Study | Shuai Yuan (+6) | 2020 | Diabetes |
| 5559 | Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population | Costin Leu (+8) | 2020 | PLOS ONE |
| 5627 | Psychotic-like experiences, polygenic risk scores for schizophrenia, and structural properties of the salience, default mode, and central-executive networks in healthy participants from UK Biobank | C. Alloza (+13) | 2020 | Translational Psychiatry |
| 4386 | Body size and composition, physical activity and sedentary time in relation to endogenous hormones in premenopausal and postmenopausal women: Findings from the UK Biobank | Sandar Tin Tin (+2) | 2020 | International Journal of Cancer |
| 4989 | Genome-Wide Association Study Identifies Genetic Associations with Perceived Age | Victoria Roberts (+3) | 2020 | Journal of Investigative Dermatology |
| 5818 | The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study | Jana J. Anderson (+9) | 2020 | BMC Medicine |
| 12903 | Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels | Gerrald A Lodewijk (+4) | 2020 | Molecular Biology and Evolution |
| 3972 | Accurate and Scalable Construction of Polygenic Scores in Large Biobank Data Sets | Sheng Yang (+1) | 2020 | American Journal of Human Genetics |
| 4185 | Association of congenital cardiovascular malformation and neuropsychiatric phenotypes with 15q11.2 (BP1-BP2) deletion in the UK Biobank | Simon G. Williams (+9) | 2020 | European Journal of Human Genetics |
| 9110 | Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis | Gudjon R. Oskarsson (+37) | 2020 | Communications Biology |
| 4654 | Detecting Genotype-Population Interaction Effects by Ancestry Principal Components | Chenglong Yu (+3) | 2020 | Frontiers in Genetics |
| 4902 | Genetic Contributions to Multivariate Data-Driven Brain Networks Constructed via Source-Based Morphometry | Amanda L Rodrigue (+10) | 2020 | Cerebral Cortex |
| 5020 | Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours | Yordi J. van de Vegte (+4) | 2020 | Nature Communications |
| 6004 | White Blood Cells and Blood Pressure: A Mendelian Randomization Study | Siedlinski M et al. | 2020 | Circulation |
| 3979 | Active Tobacco Smoking Impairs Cardiac Systolic Function | Tom Hendriks (+3) | 2020 | Scientific Reports |
| 5321 | Liability threshold modeling of case-control status and family history of disease increases association power | Margaux L. A. Hujoel (+4) | 2020 | Nature Genetics |
| 5557 | Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis | H. Zhang (+13) | 2020 | Osteoporosis International |
| 5667 | Reliability and validity of the UK Biobank cognitive tests | Chloe Fawns-Ritchie (+1) | 2020 | PLOS ONE |
| 6012 | Whole-Genome Approach Discovers Novel Genetic and Nongenetic Variance Components Modulated by Lifestyle for Cardiovascular Health | Xuan Zhou (+6) | 2020 | Journal of the American Heart Association |
| 3418 | The epidemiology of regular opioid use and its association with mortality: Prospective cohort study of 466 486 UK biobank participants | Gary J Macfarlane (+3) | 2020 | EClinicalMedicine |
| 4574 | Comparison of Adopted and Nonadopted Individuals Reveals Gene-Environment Interplay for Education in the UK Biobank | Rosa Cheesman (+7) | 2020 | Psychological Science |
| 9109 | Association Between Walking Pace and Stroke Incidence | Sara Hayes (+13) | 2020 | Stroke |
| 4932 | Genetic predisposition to smoking in relation to 14 cardiovascular diseases | Susanna C Larsson (+7) | 2020 | European Heart Journal |
| 3429 | Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma | Yi Han (+12) | 2020 | Nature Communications |
| 4393 | Brain Connectome Mapping of Complex Human Traits and Their Polygenic Architecture Using Machine Learning | Maglanoc LA et al. | 2020 | Biol Psychiatry |
| 4479 | Childhood Adoption and Mental Health in Adulthood: The Role of Gene-Environment Correlations and Interactions in the UK Biobank | Lehto K et al. | 2020 | Biol Psychiatry |
| 4828 | Explaining the link between adiposity and colorectal cancer risk in men and postmenopausal women in the UK Biobank: A sequential causal mediation analysis | S. Ghazaleh Dashti (+7) | 2020 | International Journal of Cancer |
| 5097 | Grip Strength and Walking Pace and Cardiovascular Disease Risk Prediction in 406,834 UK Biobank Participants | Claire E Welsh (+11) | 2020 | Mayo Clinic Proceedings |
| 7382 | A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease | Connor A. Emdin (+40) | 2020 | PLOS Genetics |
| 5064 | Genome-wide meta-analysis identifies novel loci associated with age-related macular degeneration | Xikun Han (+5) | 2020 | Journal of Human Genetics |
| 5829 | The Cognitive Effects of Statins are Modified by Age | Ahmed M. Alsehli (+4) | 2020 | Scientific Reports |
| 4093 | Assessing Digital Phenotyping to Enhance Genetic Studies of Human Diseases | Christopher DeBoever (+5) | 2020 | American Journal of Human Genetics |
| 5426 | Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors | James H. Cole | 2020 | Neurobiology of Aging |
| 5514 | Parity is associated with cognitive function and brain age in both females and males | Kaida Ning (+7) | 2020 | Scientific Reports |
| 4304 | Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study | Zhi-Hao Li (+18) | 2020 | Annals of the Rheumatic Diseases |
| 3883 | A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank | Weihua Meng (+15) | 2020 | Human Molecular Genetics |
| 4436 | Causal associations of thyroid function and dysfunction with overall, breast and thyroid cancer: A two-sample Mendelian randomization study | Shuai Yuan (+6) | 2020 | International Journal of Cancer |
| 3394 | Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration | Joana A. Revez (+20) | 2020 | Nature Communications |
| 2382 | Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease | Trinder M et al. | 2020 | JAMA Cardiol |
| 3936 | A prospective study of coffee and tea consumption and the risk of glioma in the UK Biobank | Creed JH et al. | 2020 | Eur J Cancer |
| 4167 | Association between TV viewing and heart disease mortality: observational study using negative control outcome | Hamer M et al. | 2020 | J Epidemiol Community Health |
| 4186 | Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition | Writing Committee for the ENIGMA-CNV Working Group (+132) | 2020 | JAMA Psychiatry |
| 4213 | Association of Nongenetic Factors With Breast Cancer Risk in Genetically Predisposed Groups of Women in the UK Biobank Cohort | Al Ajmi K et al. | 2020 | JAMA Netw Open |
| 4227 | Association of Rare Pathogenic DNA Variants for Familial Hypercholesterolemia, Hereditary Breast and Ovarian Cancer Syndrome, and Lynch Syndrome With Disease Risk in Adults According to Family History | Patel AP et al. | 2020 | JAMA Netw Open |
| 4497 | Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses | Murphy N et al. | 2020 | Gastroenterology |
| 5159 | Hypothalamic Paraventricular Nucleus Gαi2 (Guanine Nucleotide-Binding Protein Alpha Inhibiting Activity Polypeptide 2) Protein-Mediated Neural Control of the Kidney and the Salt Sensitivity of Blood Pressure | Carmichael CY et al. | 2020 | Hypertension |
| 5198 | Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study | Emanuelsson F et al. | 2020 | Diabetes Care |
| 5264 | Interpretation of risk loci from genome-wide association studies of Alzheimer's disease | Andrews SJ et al. | 2020 | Lancet Neurol |
| 5567 | Polygenic Hyperlipidemias and Coronary Artery Disease Risk | Ripatti P et al. | 2020 | Circ Genom Precis Med |
| 5656 | Reference values for skeletal muscle mass and fat mass measured by bioelectrical impedance in 390 565 UK adults | Lee MM et al. | 2020 | J Cachexia Sarcopenia Muscle |
| 5770 | Socioeconomic Status in Relation to Risks of Major Gastrointestinal Cancers in Chinese Adults: A Prospective Study of 0.5 Million People | Pang Y et al. | 2020 | Cancer Epidemiol Biomarkers Prev |
| 5795 | Taking One Step Back in Familial Hypercholesterolemia: STAP1 Does Not Alter Plasma LDL (Low-Density Lipoprotein) Cholesterol in Mice and Humans | Loaiza N et al. | 2020 | Arterioscler Thromb Vasc Biol |
| 5927 | Two novel pleiotropic loci associated with osteoporosis and abdominal obesity | Lu Liu (+13) | 2020 | Human Genetics |
| 5902 | Thousands of missing variants in the UK Biobank are recoverable by genome realignment | Tongqiu Jia (+4) | 2020 | Annals of Human Genetics |
| 4870 | Functional Annotations of Single-Nucleotide Polymorphism (SNP)-Based and Gene-Based Genome-Wide Association Studies Show Genes Affecting Keratitis Susceptibility | Yue Xu (+6) | 2020 | Medical Science Monitor |
| 7503 | Association between exposure to air pollution and thalamus volume in adults: A cross-sectional study | Dawson W. Hedges (+4) | 2020 | PLOS ONE |
| 9107 | Minimal phenotyping yields genome-wide association signals of low specificity for major depression | Na Cai (+31) | 2020 | Nature Genetics |
| 9108 | Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study | Yao Hu (+52) | 2020 | PLOS Genetics |
| 5471 | Non-additive (dominance) effects of genetic variants associated with refractive error and myopia | Alfred Pozarickij (+2) | 2020 | Molecular Genetics and Genomics |
| 5576 | Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases | Laurence J Howe (+7) | 2020 | Human Molecular Genetics |
| 4696 | Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction | Saori Sakaue (+19) | 2020 | Nature Communications |
| 4811 | Evaluation of the Host Genetic Effects of Tuberculosis-Associated Variants Among Patients With Type 1 and Type 2 Diabetes Mellitus | Huimin Zhong (+6) | 2020 | Open Forum Infectious Diseases |
| 5152 | How Does Obesity Influence the Risk of Vertebral Fracture? Findings From the UK Biobank Participants | Jin Luo (+1) | 2020 | JBMR Plus |
| 4293 | Associations of Food Outlet Densities with Obesity Measures Identify Fish and Chip Shops as a Uniquely Important Problem | Ahmad Albalawi (+2) | 2020 | Nutrients |
| 7636 | Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan | Wayne Tilley (+15) | 2020 | Nature Communications |
| 5183 | Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study | Maria C. Magnus (+11) | 2020 | BMC Medicine |
| 5914 | Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan | Saori Sakaue (+13) | 2020 | Nature Medicine |
| 2364 | Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes | Jean Shin (+69) | 2020 | Cerebral Cortex |
| 4852 | Fast and robust ancestry prediction using principal component analysis | Daiwei Zhang (+2) | 2020 | Bioinformatics |
| 5705 | Self-reported hearing loss questions provide a good measure for genetic studies: a polygenic risk score analysis from UK Biobank | Stacey S. Cherny (+6) | 2020 | European Journal of Human Genetics |
| 7637 | Predicting Body Mass Index From Structural MRI Brain Images Using a Deep Convolutional Neural Network | Pál Vakli (+3) | 2020 | Frontiers in Neuroinformatics |
| 12904 | Investigating the genetic and causal relationship between initiation or use of alcohol, caffeine, cannabis and nicotine | Lun-Hsien Chang (+10) | 2020 | Drug and Alcohol Dependence |
| 2183 | Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations | Joanne B. Cole (+2) | 2020 | Nature Communications |
| 5016 | Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error | Qiao Fan (+57) | 2020 | Communications Biology |
| 5640 | Rapid, Phase-free Detection of Long Identity-by-Descent Segments Enables Effective Relationship Classification | Daniel N Seidman (+10) | 2020 | American Journal of Human Genetics |
| 7504 | Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism | Zhonggang Li (+18) | 2020 | Cell Metabolism |
| 3849 | 10,000 social brains: Sex differentiation in human brain anatomy | Hannah Kiesow (+8) | 2020 | Science Advances |
| 4291 | Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants | Ho FK et al. | 2020 | BMJ |
| 5013 | Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank | Thorhildur Olafsdottir (+30) | 2020 | Communications Biology |
| 3413 | Estimating physical activity from self-reported behaviours in large-scale population studies using network harmonisation: findings from UK Biobank and associations with disease outcomes | Matthew Pearce (+8) | 2020 | International Journal of Behavioral Nutrition and Physical Activity |
| 4139 | Association between Exposure to Air Pollution and Total Gray Matter and Total White Matter Volumes in Adults: A Cross-Sectional Study | Lance D. Erickson (+4) | 2020 | Brain Sciences |
| 4144 | Association between habitual coffee consumption and multiple disease outcomes: A Mendelian randomisation phenome-wide association study in the UK Biobank | Konstance Nicolopoulos (+3) | 2020 | Clinical Nutrition |
| 4616 | CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake | Andrew R. McEwan (+13) | 2020 | Molecular Psychiatry |
| 5629 | Quantification of the overall contribution of gene-environment interaction for obesity-related traits | Jonathan Sulc (+8) | 2020 | Nature Communications |
| 3276 | Associations of air pollution with obesity and body fat percentage, and modification by polygenic risk score for BMI in the UK Biobank | Melissa A Furlong (+1) | 2020 | Environmental Research |
| 3871 | A Fast and Simple Method for Detecting Identity-by-Descent Segments in Large-Scale Data | Ying Zhou (+2) | 2020 | American Journal of Human Genetics |
| 5695 | Sarcopenic obesity and its association with respiratory disease incidence and mortality | Fanny Petermann-Rocha (+5) | 2020 | Clinical Nutrition |
| 3268 | Association of injury related hospital admissions with commuting by bicycle in the UK: prospective population based study | Claire Welsh (+10) | 2020 | The BMJ |
| 4138 | Association between exposure to air pollution and prefrontal cortical volume in adults: A cross-sectional study from the UK biobank | Shawn D Gale (+4) | 2020 | Environmental Research |
| 4588 | Comprehensive assessment of PINK1 variants in Parkinson's disease | Lynne Krohn (+10) | 2020 | Neurobiology of Aging |
| 3689 | Assessing Risks of Polypharmacy Involving Medications With Anticholinergic Properties | Peter Hanlon (+10) | 2020 | The Annals of Family Medicine |
| 9106 | The influence of rare variants in circulating metabolic biomarkers | Fernando Riveros-Mckay (+13) | 2020 | PLOS Genetics |
| 7505 | Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features | John P. Ray (+15) | 2020 | Nature Communications |
| 4392 | Brain aging comprises many modes of structural and functional change with distinct genetic and biophysical associations | Stephen M Smith (+6) | 2020 | eLife |
| 4297 | Associations of habitual fish oil supplementation with cardiovascular outcomes and all cause mortality: evidence from a large population based cohort study | Zhi-Hao Li (+15) | 2020 | The BMJ |
| 1922 | Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression | Glanville KP et al. | 2020 | Biol Psychiatry |
| 2223 | Fully Automated, Quality-Controlled Cardiac Analysis From CMR: Validation and Large-Scale Application to Characterize Cardiac Function | Ruijsink B et al. | 2020 | JACC Cardiovasc Imaging |
| 2889 | Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank: Observational and Mendelian Randomization Analyses | Zanetti D et al. | 2020 | Hypertension |
| 2892 | Cannabis use, depression and self-harm: phenotypic and genetic relationships | Hodgson K et al. | 2020 | Addiction |
| 3641 | Risk factors for surgery due to rotator cuff disease in a population-based cohort | Yanik EL et al. | 2020 | Bone Joint J |
| 4805 | Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis | Richardson TG et al. | 2020 | PLoS Med |
| 4944 | Genetic susceptibility to asthma increases the vulnerability to indoor air pollution | Hüls A et al. | 2020 | Eur Respir J |
| 4957 | Genetically Determined ABO Blood Group and its Associations With Health and Disease | Groot HE et al. | 2020 | Arterioscler Thromb Vasc Biol |
| 9105 | Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis | Richard J. Allen (+65) | 2020 | American Journal of Respiratory and Critical Care Medicine |
| 3904 | A Large-Scale Genetic Correlation Scan Between Intelligence and Brain Imaging Phenotypes | Shiqiang Cheng (+11) | 2020 | Cerebral Cortex |
| 5561 | Polygenic Architecture of Human Neuroanatomical Diversity | Anne Biton (+24) | 2020 | Cerebral Cortex |
| 7638 | Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure | Marios Arvanitis (+12) | 2020 | Nature Communications |
| 2581 | Multi-resolution localization of causal variants across the genome | Matteo Sesia (+4) | 2020 | Nature Communications |
| 4397 | Brainstem volume mediates seasonal variation in depressive symptoms: A cross sectional study in the UK Biobank cohort | Naif A. Majrashi (+2) | 2020 | Scientific Reports |
| 5005 | Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length | Chen Li (+95) | 2020 | American Journal of Human Genetics |
| 5419 | Mosaic chromosome Y loss is associated with alterations in blood cell counts in UK Biobank men | Shu-Hong Lin (+7) | 2020 | Scientific Reports |
| 7506 | Commentary: Correction procedures in brain-age prediction | Ann-Marie G. de Lange (+1) | 2020 | NeuroImage Clinical |
| 4537 | Cognitive functioning and lifetime major depressive disorder in UK Biobank | de Nooij L et al. | 2020 | Eur Psychiatry |
| 5764 | Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways | Emily Jamieson (+13) | 2020 | American Journal of Human Genetics |
| 5280 | Iron Status and Cancer Risk in UK Biobank: A Two-Sample Mendelian Randomization Study | Shuai Yuan (+7) | 2020 | Nutrients |
| 5704 | Self-reported and objectively measured physical activity in people with and without chronic heart failure: UK Biobank analysis | O'Donnell J et al. | 2020 | Open Heart |
| 4738 | Drink types unmask the health risks associated with alcohol intake - Prospective evidence from the general population | Rudolph Schutte (+7) | 2020 | Clinical Nutrition |
| 5827 | The causal relationships of device-measured physical activity with bipolar disorder and schizophrenia in adults: A 2-Sample mendelian randomization study | Sun H et al. | 2020 | J Affect Disord |
| 5240 | Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank | Adrián I. Campos (+5) | 2020 | Nature Communications |
| 5477 | Novel artificial neural network and linear regression based equation for estimating visceral adipose tissue volume | Ling Lin (+3) | 2020 | Clinical Nutrition |
| 9104 | Deep-learning-based prediction of late age-related macular degeneration progression | Qi Yan (+7) | 2020 | Nature Machine Intelligence |
| 5025 | Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci | Despoina Manousaki (+10) | 2020 | American Journal of Human Genetics |
| 5502 | Optimising network modelling methods for fMRI | Usama Pervaiz (+3) | 2020 | NeuroImage |
| 2839 | Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis | Batty GD et al. | 2020 | BMJ |
| 4599 | Contribution of de novo and inherited rare CNVs to very preterm birth | Hilary S Wong (+6) | 2020 | Journal of Medical Genetics |
| 5309 | Large-scale Quality Control of Cardiac Imaging in Population Studies: Application to UK Biobank | Giacomo Tarroni (+7) | 2020 | Scientific Reports |
| 12905 | Genetic control of variability in subcortical and intracranial volumes | Aldo Córdova-Palomera (+39) | 2020 | Molecular Psychiatry |
| 5963 | Using human genetics to understand the disease impacts of testosterone in men and women | Katherine S Ruth (+21) | 2020 | Nature Medicine |
| 2583 | Associations of cigarette smoking with gray and white matter in the UK Biobank | Joshua C. Gray (+5) | 2020 | Neuropsychopharmacology |
| 2664 | Mental health in UK Biobank - development, implementation and results from an online questionnaire completed by 157 366 participants: a reanalysis | Davis KAS et al. | 2020 | BJPsych Open |
| 4208 | Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis | Arsenault BJ et al. | 2020 | JAMA Netw Open |
| 3977 | ACE and Type 2 Diabetes Risk: A Mendelian Randomization Study | Marie Pigeyre (+7) | 2020 | Diabetes Care |
| 9103 | Expression quantitative trait loci-derived scores and white matter microstructure in UK Biobank: a novel approach to integrating genetics and neuroimaging | Miruna C. Barbu (+10) | 2020 | Translational Psychiatry |
| 9101 | Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits | Maria Niarchou (+8) | 2020 | Translational Psychiatry |
| 9102 | Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank | Daniela Zanetti (+5) | 2020 | Hypertension |
| 1890 | Fully Automated Myocardial Strain Estimation from Cardiovascular MRI-tagged Images Using a Deep Learning Framework in the UK Biobank | Edward Ferdian (+11) | 2020 | Radiology Cardiothoracic Imaging |
| 2623 | Impact of follow-up time and analytical approaches to account for reverse causality on the association between physical activity and health outcomes in UK Biobank | Strain T et al. | 2020 | Int J Epidemiol |
| 3691 | Associations between chronotype, MTNR1B genotype and risk of type 2 diabetes in UK Biobank | Tan X et al. | 2020 | J Intern Med |
| 4429 | Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank | Strawbridge RJ et al. | 2020 | Arterioscler Thromb Vasc Biol |
| 4675 | Diet and colorectal cancer in UK Biobank: a prospective study | Bradbury KE et al. | 2020 | Int J Epidemiol |
| 4949 | Genetic variants that associate with cirrhosis have pleiotropic effects on human traits | Chen VL et al. | 2020 | Liver Int |
| 5164 | Identification of Circulating Proteins Associated With Blood Pressure Using Mendelian Randomization | Thériault S et al. | 2020 | Circ Genom Precis Med |
| 5171 | Identification of patients with atrial fibrillation: a big data exploratory analysis of the UK Biobank | Julien Oster (+6) | 2020 | Physiological Measurement |
| 5368 | Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension | Ulrich A et al. | 2020 | Eur Respir J |
| 5739 | Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank | Zhu Z et al. | 2020 | J Allergy Clin Immunol |
| 12906 | Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians | Yingchang Lu (+51) | 2020 | Cancer Epidemiology Biomarkers & Prevention |
| 4228 | Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants | Kaida Ning (+4) | 2020 | Scientific Reports |
| 5568 | Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes | Tianyuan Lu (+7) | 2020 | Cardiovascular Diabetology |
| 5980 | Variable prediction accuracy of polygenic scores within an ancestry group | Hakhamanesh Mostafavi (+5) | 2020 | eLife |
| 5068 | Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts | Elizabeth T. Cirulli (+12) | 2020 | Nature Communications |
| 5087 | Glucosamine Use, Inflammation, and Genetic Susceptibility, and Incidence of Type 2 Diabetes: A Prospective Study in UK Biobank | Hao Ma (+7) | 2020 | Diabetes Care |
| 9091 | Genomic influences on self-reported childhood maltreatment | Shareefa Dalvie (+65) | 2020 | Translational Psychiatry |
| 9100 | Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control | James Boocock (+19) | 2020 | Human Molecular Genetics |
| 2691 | Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank | Jonathan R. I. Coleman (+25) | 2020 | Molecular Psychiatry |
| 5875 | The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly | Mark Pinese (+37) | 2020 | Nature Communications |
| 12907 | Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol | Marios K Georgakis (+5) | 2020 | Brain |
| 9090 | Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort | Gull Rukh (+5) | 2020 | Translational Psychiatry |
| 4771 | Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis | Thorunn A. Olafsdottir (+34) | 2020 | Nature Communications |
| 5172 | Identification of PIEZO1 polymorphisms for human bone mineral density | Wei-Yang Bai (+9) | 2020 | Bone |
| 5439 | Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression | Jamie E. Craig (+58) | 2020 | Nature Genetics |
| 5566 | Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples | Emma C. Johnson (+32) | 2020 | Psychological Medicine |
| 4155 | Association between physical activity and risk of incident arrhythmias in 402 406 individuals: evidence from the UK Biobank cohort | Adrian D Elliott (+10) | 2020 | European Heart Journal |
| 5413 | Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results From a National Biobank | Choi SH et al. | 2020 | Circ Res |
| 5851 | The genetic and environmental hierarchical structure of anxiety and depression in the UK Biobank | Genevieve Morneau-Vaillancourt (+6) | 2020 | Depression and Anxiety |
| 4872 | Functional validity, role, and implications of heavy alcohol consumption genetic loci | Andrew Thompson (+8) | 2020 | Science Advances |
| 4920 | Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis | Bick AG et al. | 2020 | Circulation |
| 4911 | Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank | Lars Lind | 2020 | Metabolic Syndrome and Related Disorders |
| 5501 | Operating Characteristics of the Rank-Based Inverse Normal Transformation for Quantitative Trait Analysis in Genome-Wide Association Studies | Zachary R. McCaw (+4) | 2020 | Biometrics |
| 7521 | Improving cardiac MRI convolutional neural network segmentation on small training datasets and dataset shift: A continuous kernel cut approach | Fumin Guo (+6) | 2020 | Medical Image Analysis |
| 4918 | Genetic Factors, Adherence to Healthy Lifestyle Behavior, and Risk of Invasive Breast Cancer Among Women in the UK Biobank | Rhonda S Arthur (+4) | 2020 | Journal of the National Cancer Institute |
| 5208 | Impact of sex hormone-binding globulin on the human phenome | Ryan Arathimos (+4) | 2020 | Human Molecular Genetics |
| 5540 | Physical activity and breast cancer risk: results from the UK Biobank prospective cohort | Wenji Guo (+3) | 2020 | British Journal of Cancer |
| 5840 | The effect of network thresholding and weighting on structural brain networks in the UK Biobank | Colin R Buchanan (+7) | 2020 | NeuroImage |
| 5012 | Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure | Shah S et al. | 2020 | Nat Commun |
| 3911 | A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function | Francesco Casanova (+12) | 2020 | Diabetes |
| 4847 | Factors associated with sarcopenia: A cross-sectional analysis using UK Biobank | Fanny Petermann-Rocha (+5) | 2020 | Maturitas |
| 5226 | Increased Burden of Common Risk Alleles in Children With a Significant Fracture History | Despoina Manousaki (+10) | 2020 | Journal of Bone and Mineral Research |
| 4382 | Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study | Larsson SC et al. | 2020 | Eur Heart J |
| 5190 | Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility | Linda Kachuri (+50) | 2020 | Nature Communications |
| 5833 | The dichotomous role of epiregulin in pain. | Vivek Verma (+6) | 2020 | Pain |
| 5613 | Progression of Arterial Stiffness is Associated With Midlife Diastolic Blood Pressure and Transition to Late-Life Hypertensive Phenotypes | Alastair John Stewart Webb | 2020 | Journal of the American Heart Association |
| 5966 | Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration | Xikun Han (+5) | 2020 | European Journal of Epidemiology |
| 9089 | Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia | Crystal ManYing Lee (+45) | 2020 | Obesity Reviews |
| 2143 | Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease | Trinder M et al. | 2020 | Arterioscler Thromb Vasc Biol |
| 2841 | The impact of glycated hemoglobin on risk of hypertension: a Mendelian randomization study using UK Biobank | Au Yeung SL et al. | 2020 | J Hypertens |
| 3403 | Alzheimer's Disease Susceptibility Gene Apolipoprotein E (APOE) and Blood Biomarkers in UK Biobank (N = 395,769). | Amy C Ferguson (+17) | 2020 | Journal of Alzheimer's Disease |
| 3610 | Factors in Color Fundus Photographs That Can Be Used by Humans to Determine Sex of Individuals | Yamashita T et al. | 2020 | Transl Vis Sci Technol |
| 3855 | A brief history of human disease genetics | Claussnitzer M et al. | 2020 | Nature |
| 4159 | Association Between Polygenic Risk Score and Risk of Myopia | Ghorbani Mojarrad N et al. | 2020 | JAMA Ophthalmol |
| 4507 | Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank. | Longcai Wang (+6) | 2020 | Journal of Alzheimer's Disease |
| 4575 | Comparison of Associations with Different Macular Inner Retinal Thickness Parameters in a Large Cohort: The UK Biobank | Khawaja AP et al. | 2020 | Ophthalmology |
| 4837 | Exploring the Effects of Cigarette Smoking on Inflammatory Bowel Disease Using Mendelian Randomization | Daniel P Jones (+5) | 2020 | Crohn's & Colitis 360 |
| 5174 | Identification of potential candidate genes and pathways in atrioventricular nodal reentry tachycardia by whole-exome sequencing | Luo R et al. | 2020 | Clin Transl Med |
| 5286 | Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity? | Lawson DJ et al. | 2020 | Hum Genet |
| 5311 | Leisure-time physical activity and life expectancy in people with cardiometabolic multimorbidity and depression | Chudasama YV et al. | 2020 | J Intern Med |
| 5312 | Leukocyte profiles across the cardiovascular disease continuum: A population-based cohort study | Groot HE et al. | 2020 | J Mol Cell Cardiol |
| 5408 | Modifiable pathways for colorectal cancer: a mendelian randomisation analysis | Cornish AJ et al. | 2020 | Lancet Gastroenterol Hepatol |
| 5435 | Multiple Linear Regression Allows Weighted Burden Analysis of Rare Coding Variants in an Ethnically Heterogeneous Population | David Curtis | 2020 | Human Heredity |
| 5529 | Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies | Unlu G et al. | 2020 | Nat Med |
| 5983 | Variants in ACE2 and TMPRSS2 Genes Are Not Major Determinants of COVID-19 Severity in UK Biobank Subjects | David Curtis | 2020 | Human Heredity |
| 9159 | Automated quantification of myocardial tissue characteristics from native T1 mapping using neural networks with uncertainty-based quality-control | Esther Puyol-Antón (+7) | 2020 | Journal of Cardiovascular Magnetic Resonance |
