| Title: | Impact of Genetically Predicted Red Blood Cell Traits on Venous Thromboembolism: Multivariable Mendelian Randomization Study Using UK Biobank |
| Journal: | J Am Heart Assoc |
| Published: | 21 Jul 2020 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/32635790/ |
| DOI: | https://doi.org/10.1161/JAHA.120.016771 |
Publication 3620
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Abstract
Using Mendelian randomization, our study suggests that haemoglobin (HGB) is the key red blood cell trait causing venous thromboembolism (VTE). Given men have higher HGB than women, this finding may help explain the sexual disparity in VTE rates. The benefits of therapies and other factors that raise HGB need to be weighed against their risks.1 Author
- Luo S et al.
1 Application
| Application ID | Title |
|---|---|
| 14864 | Evaluation of the causal relation between hematocrit, hemoglobin, HbA1c, testosterone and cardiovascular outcomes in the UK Biobank using Mendelian randomization analysis |
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