| Title: | Association between childhood maltreatment and the prevalence and complexity of multimorbidity: A cross-sectional analysis of 157,357 UK Biobank participants |
| Journal: | J Comorb |
| Published: | 31 Jul 2020 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/32844098/ |
| DOI: | https://doi.org/10.1177/2235042X10944344 |
Publication 3687
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Abstract
Background:Child maltreatment is associated with long-term conditions (LTCs) in adulthood. Its relationship to multimorbidity (>=2 LTCs) is less clear. We explore the relationship between child maltreatment, multimorbidity and factors complicating management.
Methods:
Cross-sectional analysis of 157,357 UK Biobank participants. Experience of four maltreatment types (physical/sexual/emotional/neglect) was identified. We explored the relationship between type, number and frequency of maltreatment and LTC count (0, 1, 2, 3, >=4) using multinomial logistic regression. Binary logistic regression assessed the relationship between maltreatment and self-rated health, loneliness, social isolation, frailty and widespread pain in those with multimorbidity, adjusting for sociodemographics and lifestyle factors.
Results:
52,675 participants (33%) experienced >=1 type of maltreatment; 983 (0.6%) experienced all four. Type, frequency and number of types of maltreatment were associated with higher LTC count. People experiencing four types of maltreatment were 5 times as likely to have a LTC count of >=4 as those experiencing none (odds ratio (OR): 5.16; 99% confidence interval (CI): 3.77-7.07). Greater number of types of maltreatment was associated with higher prevalence of combined physical/mental health LTCs (OR: 2.99; 99% CI: 2.54-3.51 for four types of maltreatment). Compared to people who reported no maltreatment, people experiencing all four types of maltreatment were more likely to have poor self-rated health (OR: 3.56; 99% CI: 2.58-4.90), loneliness (OR: 3.16; 99% CI: 2.17-4.60), social isolation (OR: 1.45; 99% CI: 1.03-2.05), widespread pain (OR: 3.19; 99% CI: 1.87-5.44) and frailty (OR: 3.21; 99% CI: 2.04-5.05).
Conclusion:
People with a history of maltreatment have higher LTC counts and potentially more complicated management needs reinforcing calls for early intervention.
1 Author
- Hanlon P et al.
1 Application
| Application ID | Title |
|---|---|
| 14151 | Exploring multimorbidity in UK Biobank ? patterns of illness reporting and effects of comorbidity and multimorbidity on health outcomes |
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