Pub ID | Title | Author(s) | Year | Journal |
3135 | Systematic drug repurposing to enable precision medicine: A case study in breast cancer | Taylor et al. | 2019 | Digital Medicine (2019) |
2730 | Social engagement after stroke - is it relevant to cognitive function? A cross-sectional analysis of UK Biobank data | Drozdowska et al | 2019 | AMRC Open Research (2019) |
5457 | Neuroticism, health and health behaviours in emergency personnel: a UK Biobank study | M Mutambudzi (+2) | 2019 | Occupational Medicine |
5200 | Impact of glycemic traits, type 2 diabetes and metformin use on breast and prostate cancer risk: a Mendelian randomization study | Au Yeung SL et al. | 2019 | BMJ Open Diabetes Res Care |
5493 | Objective sleep assessment in >80,000 UK mid-life adults: Associations with sociodemographic characteristics, physical activity and caffeine | Gewei Zhu (+7) | 2019 | PLOS ONE |
5506 | Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale | Christopher A. German (+4) | 2019 | Genetic Epidemiology |
4224 | Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease | Honigberg MC et al. | 2019 | JAMA |
5178 | Identifying cross-disease components of genetic risk across hospital data in the UK Biobank | Adrian Cortes (+4) | 2019 | Nature Genetics |
2385 | Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke | Abraham G et al. | 2019 | Nat Commun |
5847 | The emerging landscape of health research based on biobanks linked to electronic health records: Existing resources, statistical challenges, and potential opportunities | Lauren J. Beesley (+8) | 2019 | Statistics in Medicine |
4315 | Associations with photoreceptor thickness measures in the UK Biobank | Chua SYL et al. | 2019 | Sci Rep |
7639 | Genotype-free demultiplexing of pooled single-cell RNA-seq | Jun Xu (+17) | 2019 | Genome Biology |
2844 | Association Between Recreational Cannabis Use and Cardiac Structure and Function | Mohammed Y. Khanji (+15) | 2019 | JACC Cardiovascular Imaging |
4601 | Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study | Mirthe Muilwijk (+14) | 2019 | BMJ Open Diabetes Research & Care |
4994 | Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income | Hill WD et al. | 2019 | Nat Commun |
3887 | A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio | Casanova F et al. | 2019 | Hum Mol Genet |
5619 | Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health | Qian Yang (+2) | 2019 | International Journal of Epidemiology |
7325 | Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. | Katerina Zorina-Lichtenwalter (+2) | 2019 | Pain |
5554 | Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study | Yuan S et al. | 2019 | Nutrients |
3868 | A Fast and Accurate Method for Genome-wide Scale Phenome-wide G × E Analysis and Its Application to UK Biobank | Bi W et al. | 2019 | Am J Hum Genet |
5054 | Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2 | Hernandez Cordero AI et al. | 2019 | Am J Hum Genet |
5353 | Making the Most of Clumping and Thresholding for Polygenic Scores | Privé F et al. | 2019 | Am J Hum Genet |
3379 | Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure | Ward J et al. | 2019 | Transl Psychiatry |
7324 | Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction | Nathan R. Treff (+10) | 2019 | Frontiers in Endocrinology |
5337 | Long-Term Cardiovascular Risk in Women With Hypertension During Pregnancy | Honigberg MC et al. | 2019 | J Am Coll Cardiol |
4303 | Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance | Suzuki H et al. | 2019 | JAMA Netw Open |
5325 | LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels | Leinonen JT et al. | 2019 | Sci Rep |
3273 | Deep Learning and Glaucoma Specialists: The Relative Importance of Optic Disc Features to Predict Glaucoma Referral in Fundus Photographs | Phene S et al. | 2019 | Ophthalmology |
3631 | Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies | Nalls MA et al. | 2019 | Lancet Neurol |
4052 | Integrated Multiomics Approach to Identify Genetic Underpinnings of Heart Failure and Its Echocardiographic Precursors: Framingham Heart Study | Andersson C et al. | 2019 | Circ Genom Precis Med |
4194 | Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits | Legge SE et al. | 2019 | JAMA Psychiatry |
4306 | Associations of Retinal Microvascular Diameters and Tortuosity With Blood Pressure and Arterial Stiffness: United Kingdom Biobank | Tapp RJ et al. | 2019 | Hypertension |
4311 | Associations of Smoking and Alcohol and Coffee Intake with Fracture and Bone Mineral Density: A Mendelian Randomization Study | Yuan S et al. | 2019 | Calcif Tissue Int |
4644 | Depression increases the genetic susceptibility to high body mass index: Evidence from UK Biobank | Mulugeta A et al. | 2019 | Depress Anxiety |
4904 | Genetic correlates of social stratification in Great Britain | Abdellaoui A et al. | 2019 | Nat Hum Behav |
4912 | Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation | Allara E et al. | 2019 | Circ Genom Precis Med |
5007 | Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema | Johansson Å et al. | 2019 | Hum Mol Genet |
5051 | Genome-Wide Association Study of the Metabolic Syndrome in UK Biobank | Lind L | 2019 | Metab Syndr Relat Disord |
5145 | Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study | Wainberg M et al. | 2019 | PLoS Med |
5395 | Metabolites downstream of predicted loss-of-function variants inform relationship to disease | Li M et al. | 2019 | Mol Genet Metab |
5447 | Multivariate genome-wide analysis of stress-related quantitative phenotypes | Schijven D et al. | 2019 | Eur Neuropsychopharmacol |
5456 | Neuroticism as a Predictor of Frailty in Old Age: A Genetically Informative Approach | Daníelsdóttir HB et al. | 2019 | Psychosom Med |
5560 | Pneumonia: host susceptibility and shared genetics with pulmonary function and other traits | Khadzhieva MB et al. | 2019 | Clin Exp Immunol |
5590 | Predicting incident dementia 3-8 years after brief cognitive tests in the UK Biobank prospective study of 500,000 people | Calvin CM et al. | 2019 | Alzheimers Dement |
5666 | Relevance of physical function in the association of red and processed meat intake with all-cause, cardiovascular, and cancer mortality | Argyridou S et al. | 2019 | Nutr Metab Cardiovasc Dis |
5742 | Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis | Zhu Z et al. | 2019 | Eur Respir J |
5797 | Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants | Kuo CL et al. | 2019 | Aging Cell |
5954 | Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations | Kowalski MH et al. | 2019 | PLoS Genet |
5976 | Validation of Cardiovascular Magnetic Resonance-Derived Equation for Predicted Left Ventricular Mass Using the UK Biobank Imaging Cohort: Tool for Donor-Recipient Size Matching | Fung K et al. | 2019 | Circ Heart Fail |
7507 | Mapping ICD-10 and ICD-10-CM Codes to Phecodes: Workflow Development and Initial Evaluation | Patrick Wu (+11) | 2019 | JMIR Medical Informatics |
3976 | Accurate, scalable and integrative haplotype estimation | Delaneau O et al. | 2019 | Nat Commun |
2283 | Brain age prediction using deep learning uncovers associated sequence variants | Jonsson BA et al. | 2019 | Nat Commun |
5442 | Multi-trait genome-wide association study identifies new loci associated with optic disc parameters | Bonnemaijer PWM et al. | 2019 | Commun Biol |
5206 | Impact of Rheumatoid Arthritis and Its Management on Falls, Fracture and Bone Mineral Density in UK Biobank | Clynes MA et al. | 2019 | Front Endocrinol (Lausanne) |
3678 | A resource-efficient tool for mixed model association analysis of large-scale data | Longda Jiang (+6) | 2019 | Nature Genetics |
4629 | Deciphering the Biological Mechanisms Underlying the Genome-Wide Associations between Computerized Device Use and Psychiatric Disorders | Wendt FR et al. | 2019 | J Clin Med |
7508 | Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5 | Keira J. A. Johnston (+7) | 2019 | Translational Psychiatry |
1743 | Genetic evidence for assortative mating on alcohol consumption in the UK Biobank | Howe LJ et al. | 2019 | Nat Commun |
5463 | New versus old guidelines for sarcopenia classification: What is the impact on prevalence and health outcomes? | Fanny Petermann-Rocha (+5) | 2019 | Age and Ageing |
6006 | White Matter Microstructure and Its Relation to Longitudinal Measures of Depressive Symptoms in Mid- and Late Life | Shen X et al. | 2019 | Biol Psychiatry |
6013 | Whole-Genome Sequencing of Childhood Cancer Survivors Treated with Cranial Radiation Therapy Identifies 5p15.33 Locus for Stroke: A Report from the St. Jude Lifetime Cohort Study | Sapkota Y et al. | 2019 | Clin Cancer Res |
5417 | Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle: A UK Biobank study. | Francesco Zaccardi (+5) | 2019 | European Journal of Preventive Cardiology |
3873 | A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients. | Rodrigo Benavides (+9) | 2019 | Pain |
4165 | Association between the 4p16 genomic locus and different types of congenital heart disease: results from adult survivors in the UK Biobank | Córdova-Palomera A et al. | 2019 | Sci Rep |
3256 | Improved polygenic prediction by Bayesian multiple regression on summary statistics | Lloyd-Jones LR et al. | 2019 | Nat Commun |
3639 | Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease | Jennifer S. Lees (+13) | 2019 | Nature Medicine |
4476 | Characterization of Prevalence and Health Consequences of Uniparental Disomy in Four Million Individuals from the General Population | Nakka P et al. | 2019 | Am J Hum Genet |
4961 | Genetically Determined Physical Activity and Its Association with Circulating Blood Cells | Prins FM et al. | 2019 | Genes (Basel) |
5862 | The Human-Specific BOLA2 Duplication Modifies Iron Homeostasis and Anemia Predisposition in Chromosome 16p11.2 Autism Individuals | Giannuzzi G et al. | 2019 | Am J Hum Genet |
4755 | Effects of blood lead on coronary artery disease and its risk factors: a Mendelian Randomization study | Schooling CM et al. | 2019 | Sci Rep |
2659 | Age at natural menopause and risk of incident cardiovascular disease: a pooled analysis of individual patient data | Zhu D et al. | 2019 | Lancet Public Health |
3422 | Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits | Zhao B et al. | 2019 | Nat Genet |
3470 | Comparison of accelerometer-derived physical activity levels between individuals with and without cancer: a UK Biobank study | McDonald L et al. | 2019 | Future Oncol |
3928 | A polygenic score for body mass index is associated with depressive symptoms via early life stress: Evidence for gene-environment correlation | Avinun R et al. | 2019 | J Psychiatr Res |
4017 | Aging-related changes in fluid intelligence, muscle and adipose mass, and sex-specific immunologic mediation: A longitudinal UK Biobank study | Klinedinst BS et al. | 2019 | Brain Behav Immun |
4192 | Association of Fitness and Grip Strength With Heart Failure Findings From the UK Biobank Population-Based Study | Anne Sillars (+15) | 2019 | Mayo Clinic Proceedings |
4313 | Associations with Corneal Hysteresis in a Population Cohort: Results from 96 010 UK Biobank Participants | Zhang B et al. | 2019 | Ophthalmology |
4432 | Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy | Czesnikiewicz-Guzik M et al. | 2019 | Eur Heart J |
4735 | Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study | Steell L et al. | 2019 | Br J Sports Med |
4779 | Environmental correlates of chronic obstructive pulmonary disease in 96 779 participants from the UK Biobank: a cross-sectional, observational study | Sarkar C et al. | 2019 | Lancet Planet Health |
4894 | Genetic architecture of subcortical brain structures in 38,851 individuals | Satizabal CL et al. | 2019 | Nat Genet |
4931 | Genetic predisposition to mosaic Y chromosome loss in blood | Thompson DJ et al. | 2019 | Nature |
5008 | Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology | Han X et al. | 2019 | Hum Mol Genet |
5011 | Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease | Klarin D et al. | 2019 | Nat Genet |
5117 | Health effects associated with serum calcium concentrations: evidence from MR-PheWAS analysis in UK Biobank | Zhou A et al. | 2019 | Osteoporos Int |
5156 | Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis | Eales JM et al. | 2019 | Arterioscler Thromb Vasc Biol |
5564 | Polygenic burden in focal and generalized epilepsies | Leu C et al. | 2019 | Brain |
5808 | The association between self-reported poor oral health and gastrointestinal cancer risk in the UK Biobank: A large prospective cohort study | Jordão HW et al. | 2019 | United European Gastroenterol J |
5881 | The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM2.5) and Glaucoma in a Large Community Cohort | Chua SYL et al. | 2019 | Invest Ophthalmol Vis Sci |
4278 | Associations of autozygosity with a broad range of human phenotypes | Clark DW et al. | 2019 | Nat Commun |
5003 | Genome-Wide Assessment for Resting Heart Rate and Shared Genetics With Cardiometabolic Traits and Type 2 Diabetes | Guo Y et al. | 2019 | J Am Coll Cardiol |
5586 | Population-based neuroimaging reveals traces of childbirth in the maternal brain | de Lange AG et al. | 2019 | Proc Natl Acad Sci U S A |
5671 | Reproducibility of dietary intakes of macronutrients, specific food groups, and dietary patterns in 211 050 adults in the UK Biobank study | Carter JL et al. | 2019 | J Nutr Sci |
4855 | Female reproductive history in relation to chronic obstructive pulmonary disease and lung function in UK biobank: a prospective population-based cohort study | Tang R et al. | 2019 | BMJ Open |
3460 | Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer | Lello L et al. | 2019 | Sci Rep |
2712 | Genetic mapping and evolutionary analysis of human-expanded cognitive networks | Wei Y et al. | 2019 | Nat Commun |
4092 | Assessing Causality in Associations of Serum Calcium and Magnesium Levels With Heart Failure: A Two-Sample Mendelian Randomization Study | Helte E et al. | 2019 | Front Genet |
4732 | Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK Biobank | Einas Elmahi (+12) | 2019 | PLOS ONE |
7341 | A Spatio-Temporal Ageing Atlas of the Proximal Femur | Mohsen Farzi (+6) | 2019 | IEEE Transactions on Medical Imaging |
5625 | Psychosocial moderation of polygenic risk for cannabis involvement: the role of trauma exposure and frequency of religious service attendance | Meyers JL et al. | 2019 | Transl Psychiatry |
3501 | External Replication of Urinary Bladder Cancer Prognostic Polymorphisms in the UK Biobank | Lipunova N et al. | 2019 | Front Oncol |
4823 | Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer | Glentis S et al. | 2019 | Front Genet |
5000 | Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development | Aung N et al. | 2019 | Circulation |
5746 | Shift Workers Have Higher Blood Pressure Medicine Use, But Only When They Are Short Sleepers: A Longitudinal UK Biobank Study | Riegel B et al. | 2019 | J Am Heart Assoc |
4638 | Deep neural networks and kernel regression achieve comparable accuracies for functional connectivity prediction of behavior and demographics | Tong He (+8) | 2019 | NeuroImage |
4196 | Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease | Ference BA et al. | 2019 | JAMA |
7509 | Genetic contributions to variation in human stature in prehistoric Europe | Samantha L. Cox (+3) | 2019 | Proceedings of the National Academy of Sciences of the United States of America |
3084 | GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank | Wells HRR et al. | 2019 | Am J Hum Genet |
5204 | Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program | Sarnowski C et al. | 2019 | Am J Hum Genet |
4939 | Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition | Mark J. Adams (+9) | 2019 | Psychological Medicine |
2579 | Age at menopause and lung function: a Mendelian randomisation study | van der Plaat DA et al. | 2019 | Eur Respir J |
2823 | Cigarette smoking and personality: interrogating causality using Mendelian randomisation | Sallis HM et al. | 2019 | Psychol Med |
2824 | The effect of smoking intensity on all-cause and cause-specific mortality-a Mendelian randomization analysis | Vie GÅ et al. | 2019 | Int J Epidemiol |
2907 | The Associations of Diuretics and Laxatives Use with Cardiovascular Mortality. An Individual Patient-Data Meta-analysis of Two Large Cohort Studies | Hoppe LK et al. | 2019 | Cardiovasc Drugs Ther |
3099 | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels | Tin A et al. | 2019 | Nat Genet |
3113 | Common brain disorders are associated with heritable patterns of apparent aging of the brain | Kaufmann T et al. | 2019 | Nat Neurosci |
4027 | Alcohol intake and risk of rheumatoid arthritis: a Mendelian randomization study | Bae SC et al. | 2019 | Z Rheumatol |
4071 | Analytical strategies to include the X-chromosome in variance heterogeneity analyses: Evidence for trait-specific polygenic variance structure | Deng WQ et al. | 2019 | Genet Epidemiol |
4134 | Association between coffee consumption and overall risk of being diagnosed with or dying from cancer among >300 000 UK Biobank participants in a large-scale Mendelian randomization study | Ong JS et al. | 2019 | Int J Epidemiol |
4423 | Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics | Ramírez J et al. | 2019 | Circ Arrhythm Electrophysiol |
4449 | Causal Factors for Knee, Hip, and Hand Osteoarthritis: A Mendelian Randomization Study in the UK Biobank | Funck-Brentano T et al. | 2019 | Arthritis Rheumatol |
4459 | Causal relationships between obesity and the leading causes of death in women and men | Censin JC et al. | 2019 | PLoS Genet |
4896 | Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis | Thériault S et al. | 2019 | Circ Genom Precis Med |
4907 | Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes | Laville V et al. | 2019 | Am J Ophthalmol |
4921 | Genetic influences on treatment-seeking for common mental health problems in the UK biobank | Rayner C et al. | 2019 | Behav Res Ther |
4963 | Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study | Li X et al. | 2019 | PLoS Med |
5116 | Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics | Wiberg A et al. | 2019 | Brain |
5374 | Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures | Zheng J et al. | 2019 | J Bone Miner Res |
5421 | MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging | Millard LAC et al. | 2019 | PLoS Genet |
5533 | Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study | Meng X et al. | 2019 | Int J Epidemiol |
5547 | Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank | Folley S et al. | 2019 | J Alzheimers Dis |
5959 | Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight | Hwang LD et al. | 2019 | Int J Epidemiol |
7377 | 52 A PHENOME-WIDE ASSOCIATION AND MENDELIAN RANDOMISATION STUDY OF POLYGENIC RISK FOR DEPRESSION IN UK BIOBANK | Xueyi Shen (+7) | 2019 | European Neuropsychopharmacology |
2831 | Impact of major depression on cardiovascular outcomes for individuals with hypertension: prospective survival analysis in UK Biobank | Nicholas Graham (+6) | 2019 | BMJ Open |
2859 | The association between driving time and unhealthy lifestyles: a cross-sectional, general population study of 386 493 UK Biobank participants | Mackay A et al. | 2019 | J Public Health (Oxf) |
4630 | Deconstructing the sources of genotype-phenotype associations in humans | Alexander I Young (+3) | 2019 | Science |
7640 | A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity | Mickael Rosa (+7) | 2019 | npj Genomic Medicine |
4865 | Frequency and distribution of corneal astigmatism and keratometry features in adult life: Methodology and findings of the UK Biobank study | Nikolas Pontikos (+4) | 2019 | PLOS ONE |
1763 | Multivariable two-sample Mendelian randomization estimates of the effects of intelligence and education on health | Neil Martin Davies (+5) | 2019 | eLife |
5201 | Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study | Emanuelsson F et al. | 2019 | J Am Coll Cardiol |
7660 | Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness | Abdel Abdellaoui (+27) | 2019 | Human Molecular Genetics |
3098 | Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria | Teumer A et al. | 2019 | Nat Commun |
5752 | Sleep Duration and Myocardial Infarction | Daghlas I et al. | 2019 | J Am Coll Cardiol |
4586 | Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology | Yosuke Tanigawa (+13) | 2019 | Nature Communications |
5734 | Sex-specific Mendelian randomization study of genetically predicted insulin and cardiovascular events in the UK Biobank | Zhao JV et al. | 2019 | Commun Biol |
3934 | A Prospective Analysis of Genetic Variants Associated with Human Lifespan | Wright KM et al. | 2019 | G3 (Bethesda) |
3366 | Extreme inbreeding in a European ancestry sample from the contemporary UK population | Yengo L et al. | 2019 | Nat Commun |
2709 | Indicators of mental disorders in UK Biobank-A comparison of approaches | Davis KAS et al. | 2019 | Int J Methods Psychiatr Res |
3890 | A genome-wide association study-derived polygenic score for interleukin-1β is associated with hippocampal volume in two samples | Avinun R et al. | 2019 | Hum Brain Mapp |
4137 | Association between exposure to air pollution and hippocampal volume in adults in the UK Biobank | Hedges DW et al. | 2019 | Neurotoxicology |
4466 | Changes in Cardiac Morphology and Function in Individuals With Diabetes Mellitus: The UK Biobank Cardiovascular Magnetic Resonance Substudy | Jensen MT et al. | 2019 | Circ Cardiovasc Imaging |
4512 | Clarin-2 is essential for hearing by maintaining stereocilia integrity and function | Dunbar LA et al. | 2019 | EMBO Mol Med |
4600 | Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease | Karlsson T et al. | 2019 | Nat Med |
4660 | Determinants of impaired lung function and lung cancer prediction among never-smokers in the UK Biobank cohort | Warkentin MT et al. | 2019 | EBioMedicine |
4941 | Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration | Wilman HR et al. | 2019 | J Hepatol |
5048 | Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans | Gelernter J et al. | 2019 | Nat Neurosci |
5458 | New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders | Evangelou E et al. | 2019 | Nat Hum Behav |
5888 | The role of linoleic acid in asthma and inflammatory markers: a Mendelian randomization study | Zhao JV et al. | 2019 | Am J Clin Nutr |
5952 | Uric acid level, gout and bone mineral density: A Mendelian randomization study | Lee YH et al. | 2019 | Eur J Clin Invest |
7291 | The association of grip strength with health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study. | Frederick K W Ho (+12) | 2019 | Age and Ageing |
5306 | Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior | Ganna A et al. | 2019 | Science |
5040 | Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank | Meng W et al. | 2019 | Commun Biol |
5256 | Integrating transcriptome-wide study and mRNA expression profiles yields novel insights into the biological mechanism of chondropathies | Li P et al. | 2019 | Arthritis Res Ther |
4431 | Case-Only Analysis of Gene-Environment Interactions Using Polygenic Risk Scores | Allison Meisner (+2) | 2019 | American Journal of Epidemiology |
5857 | The genetic relationship between female reproductive traits and six psychiatric disorders | Ni G et al. | 2019 | Sci Rep |
4620 | Cross-sectional and longitudinal associations between active commuting and patterns of movement behaviour during discretionary time: A compositional data analysis | Louise Foley (+5) | 2019 | PLOS ONE |
5942 | Understanding cognitive impairment in mood disorders: mediation analyses in the UK Biobank cohort | Breda Cullen (+5) | 2019 | The British Journal of Psychiatry |
3912 | A meta-analysis of genome-wide association studies identifies multiple longevity genes | Deelen J et al. | 2019 | Nat Commun |
3391 | GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits | Raha Pazoki (+10) | 2019 | Nature Communications |
5009 | Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes | Wang H et al. | 2019 | Nat Commun |
4207 | Association of Lifestyle and Genetic Risk With Incidence of Dementia | Lourida I et al. | 2019 | JAMA |
5272 | Investigating the association between body fat and depression via Mendelian randomization | Speed MS et al. | 2019 | Transl Psychiatry |
2591 | The associations between self-reported depression, self-reported chronic inflammatory conditions and cognitive abilities in UK Biobank | Lyall LM et al. | 2019 | Eur Psychiatry |
2644 | GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores | Mullins N et al. | 2019 | Am J Psychiatry |
2946 | Driving status, travel modes and accelerometer-assessed physical activity in younger, middle-aged and older adults: a prospective study of 90 810 UK Biobank participants | Hajna S et al. | 2019 | Int J Epidemiol |
3127 | Quantitative CMR population imaging on 20,000 subjects of the UK Biobank imaging study: LV/RV quantification pipeline and its evaluation | Attar R et al. | 2019 | Med Image Anal |
3302 | Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank | Wang H et al. | 2019 | Sci Adv |
3918 | A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity | van der Lee SJ et al. | 2019 | Acta Neuropathol |
4226 | Association of Rare Copy Number Variants With Risk of Depression | Kendall KM et al. | 2019 | JAMA Psychiatry |
4247 | Associations between active travel and diet: cross-sectional evidence on healthy, low-carbon behaviours from UK Biobank | Michaela A Smith (+4) | 2019 | BMJ Open |
4720 | Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study | Celis-Morales CA et al. | 2019 | Int J Obes (Lond) |
4780 | Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations | Barfield R et al. | 2019 | Sleep |
4930 | Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study | Cerani A et al. | 2019 | BMJ |
5019 | Genome-wide association study of peripheral artery disease in the Million Veteran Program | Klarin D et al. | 2019 | Nat Med |
5648 | Rationale and tutorial for analysing and reporting sex differences in cardiovascular associations | Mark Woodward | 2019 | Heart |
5794 | Systolic Blood Pressure and Risk of Valvular Heart Disease: A Mendelian Randomization Study | Nazarzadeh M et al. | 2019 | JAMA Cardiol |
4067 | Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia | Tkatchenko TV et al. | 2019 | BMC Med Genomics |
5558 | Pleiotropy Complicates Human Gene Editing: CCR5Δ32 and Beyond | Li T et al. | 2019 | Front Genet |
7510 | Stochastic Lanczos estimation of genomic variance components for linear mixed-effects models | Richard Border (+1) | 2019 | BMC Bioinformatics |
3974 | Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture | Kangcheng Hou (+7) | 2019 | Nature Genetics |
5396 | Methylmercury exposure, genetic variation in metabolic enzymes, and the risk of glioma | Creed JH et al. | 2019 | Sci Rep |
5530 | Phenome-wide Burden of Copy-Number Variation in the UK Biobank | Matthew Aguirre (+2) | 2019 | American Journal of Human Genetics |
5641 | RaPID: ultra-fast, powerful, and accurate detection of segments identical by descent (IBD) in biobank-scale cohorts | Naseri A et al. | 2019 | Genome Biol |
5660 | Relationship Between Diet, Tinnitus, and Hearing Difficulties | Piers Dawes (+4) | 2019 | Ear & Hearing |
7511 | Normative brain volumetry derived from different reference populations: impact on single-subject diagnostic assessment in dementia | Elisabeth J. Vinke (+11) | 2019 | Neurobiology of Aging |
4276 | Associations between vascular risk factors and brain MRI indices in UK Biobank | Cox SR et al. | 2019 | Eur Heart J |
2843 | Right ventricular shape and function: cardiovascular magnetic resonance reference morphology and biventricular risk factor morphometrics in UK Biobank | Mauger C et al. | 2019 | J Cardiovasc Magn Reson |
5781 | Structural brain imaging correlates of general intelligence in UK Biobank | Cox SR et al. | 2019 | Intelligence |
3416 | A Powerful Global Test Statistic for Functional Statistical Inference. | Jingwen Zhang (+3) | 2019 | Proceedings of the AAAI Conference on Artificial Intelligence |
4087 | ARMC 5 Variants and Risk of Hypertension in Blacks: MH- GRID Study | Zilbermint M et al. | 2019 | J Am Heart Assoc |
4202 | Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms | Nima C. Emami (+11) | 2019 | Nature Communications |
6000 | Weakly supervised classification of aortic valve malformations using unlabeled cardiac MRI sequences | Jason A. Fries (+13) | 2019 | Nature Communications |
3448 | The effect of X-linked dosage compensation on complex trait variation | Julia Sidorenko (+11) | 2019 | Nature Communications |
7339 | Reconciling S-LDSC and LDAK functional enrichment estimates | Steven Gazal (+3) | 2019 | Nature Genetics |
3054 | The UKB envirome of depression: from interactions to synergistic effects | Gabor Hullam (+6) | 2019 | Scientific Reports |
4766 | Efficient haplotype matching between a query and a panel for genealogical search | Ardalan Naseri (+3) | 2019 | Bioinformatics |
4035 | Altered Cortical Brain Structure and Increased Risk for Disease Seen Decades After Perinatal Exposure to Maternal Smoking: A Study of 9000 Adults in the UK Biobank. | Lauren E Salminen (+14) | 2019 | Cerebral Cortex |
2838 | Assessment of Relative Utility of Underlying vs Contributory Causes of Death | Batty GD et al. | 2019 | JAMA Netw Open |
5369 | Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour | Sanderson E et al. | 2019 | Nat Commun |
4266 | Associations Between Measures of Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Cohort Study and Mendelian Randomization Analysis Using the UK Biobank | Farmer RE et al. | 2019 | J Am Heart Assoc |
2530 | Air pollution, lung function and COPD: results from the population-based UK Biobank study | Doiron D et al. | 2019 | Eur Respir J |
2815 | Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease | Leong A et al. | 2019 | Diabetes Care |
3207 | Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes | Freidin M et al. | 2019 | J Med Genet |
3629 | Physical activity and left ventricular trabeculation in the UK Biobank community-based cohort study | Woodbridge SP et al. | 2019 | Heart |
3861 | A commonly occurring genetic variant within the NPLOC4-TSPAN10-PDE6G gene cluster is associated with the risk of strabismus | Plotnikov D et al. | 2019 | Hum Genet |
4380 | Body Fat Distribution and Systolic Blood Pressure in 10,000 Adults with Whole-Body Imaging: UK Biobank and Oxford BioBank | Malden D et al. | 2019 | Obesity (Silver Spring) |
4395 | Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk | Alnæs D et al. | 2019 | JAMA Psychiatry |
4455 | Causal relationship between years of education and the occurrence of rheumatoid arthritis | Bae SC et al. | 2019 | Postgrad Med J |
4985 | Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank | Wang Q et al. | 2019 | EBioMedicine |
5620 | PRSice-2: Polygenic Risk Score software for biobank-scale data | Shing Wan Choi (+1) | 2019 | GigaScience |
5672 | Reserve and Alzheimer's disease genetic risk: Effects on hospitalization and mortality | Filshtein TJ et al. | 2019 | Alzheimers Dement |
5878 | The occupations at increased risk of COPD: analysis of lifetime job-histories in the population-based UK Biobank Cohort | De Matteis S et al. | 2019 | Eur Respir J |
5268 | Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study | Richmond RC et al. | 2019 | BMJ |
5344 | Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality | Benn M et al. | 2019 | J Am Coll Cardiol |
2654 | Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data | Shungin D et al. | 2019 | Nat Commun |
2856 | Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants | Fung K et al. | 2019 | Sci Rep |
4718 | Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury? | Robin B. Brown (+4) | 2019 | Stroke |
2846 | Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease: Data from UK Biobank | Claire Welsh (+15) | 2019 | Circulation |
5142 | Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank | Lisa Nobis (+6) | 2019 | NeuroImage Clinical |
4938 | Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases | Ntalla I et al. | 2019 | J Am Coll Cardiol |
4846 | Factors associated with potentially serious incidental findings and with serious final diagnoses on multi-modal imaging in the UK Biobank Imaging Study: A prospective cohort study | Lorna M. Gibson (+12) | 2019 | PLOS ONE |
7512 | Macrothrombocytopenia associated with a rare GFI1B missense variant confounding the presentation of immune thrombocytopenia | Aaron N. Cheng (+3) | 2019 | Pediatric Blood & Cancer |
7513 | Genome-wide association study of multisite chronic pain in UK Biobank | Keira J. A. Johnston (+8) | 2019 | PLOS Genetics |
3953 | A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids | Edwards TL et al. | 2019 | Front Genet |
5549 | Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study | Chudasama YV et al. | 2019 | BMC Med |
7354 | Estimation of brain age delta from brain imaging | Stephen M. Smith (+4) | 2019 | NeuroImage |
2705 | Assessing for interaction between APOE ε4, sex, and lifestyle on cognitive abilities | Lyall DM et al. | 2019 | Neurology |
2155 | Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals | Border R et al. | 2019 | Eur J Hum Genet |
2694 | Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use | Brazel DM et al. | 2019 | Biol Psychiatry |
2845 | Urinary Sodium Excretion, Blood Pressure, and Risk of Future Cardiovascular Disease and Mortality in Subjects Without Prior Cardiovascular Disease | C.E. Welsh (+11) | 2019 | Hypertension |
2882 | Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis | Thompson WD et al. | 2019 | PLoS Med |
3102 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Wuttke M et al. | 2019 | Nat Genet |
4295 | Associations of genetically determined iron status across the phenome: A mendelian randomization study | Gill D et al. | 2019 | PLoS Med |
4354 | Biological insights into multiple birth: genetic findings from UK Biobank | Mbarek H et al. | 2019 | Eur J Hum Genet |
4415 | Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank | Hindy G et al. | 2019 | Arthritis Rheumatol |
4570 | Comparative Relevance of Physical Fitness and Adiposity on Life Expectancy: A UK Biobank Observational Study | Zaccardi F et al. | 2019 | Mayo Clin Proc |
5461 | New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances | Hwang LD et al. | 2019 | Am J Clin Nutr |
5489 | Obesity, Brain Volume, and White Matter Microstructure at MRI: A Cross-sectional UK Biobank Study | Dekkers IA et al. | 2019 | Radiology |
5678 | Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans | Garske KM et al. | 2019 | Nat Metab |
5738 | Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies | Pividori M et al. | 2019 | Lancet Respir Med |
7284 | ukbtools: An R package to manage and query UK Biobank data | Ken B. Hanscombe (+3) | 2019 | PLOS ONE |
7283 | Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland | Sini Kerminen (+11) | 2019 | American Journal of Human Genetics |
4180 | Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank | Lyn D Ferguson (+8) | 2019 | Rheumatology |
7282 | Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis | Harry D Green (+12) | 2019 | Journal of Crohn's and Colitis |
5946 | Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study | Carter AR et al. | 2019 | BMJ |
2822 | Evidence for Genetic Correlations and Bidirectional, Causal Effects Between Smoking and Sleep Behaviors | Gibson M et al. | 2019 | Nicotine Tob Res |
4128 | Association between birth weight and refractive error in adulthood: a Mendelian randomisation study | Denis Plotnikov (+2) | 2019 | British Journal of Ophthalmology |
4421 | Cardiovascular disease risk prediction using automated machine learning: A prospective study of 423,604 UK Biobank participants | Ahmed M. Alaa (+4) | 2019 | PLOS ONE |
4200 | Association of habitual glucosamine use with risk of cardiovascular disease: prospective study in UK Biobank | Hao Ma (+7) | 2019 | The BMJ |
2620 | Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study | Thomas J Littlejohns (+5) | 2019 | European Urology Focus |
7661 | The relationship between sleep duration, cognition and dementia: a Mendelian randomization study | Albert Henry (+7) | 2019 | International Journal of Epidemiology |
4191 | Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study | Polimanti R et al. | 2019 | JAMA Netw Open |
4474 | Characteristics, comorbidities, and correlates of atypical depression: evidence from the UK Biobank Mental Health Survey | Anamaria Brailean (+4) | 2019 | Psychological Medicine |
2568 | Habitual coffee consumption and risk of falls in 2 European cohorts of older adults | Machado-Fragua MD et al. | 2019 | Am J Clin Nutr |
2660 | Variations in reproductive events across life: a pooled analysis of data from 505 147 women across 10 countries | InterLACE Study Team. | 2019 | Hum Reprod |
2832 | Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion | Zanetti D et al. | 2019 | Kidney Int |
2904 | Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors | Warrington NM et al. | 2019 | Nat Genet |
4072 | Anatomical selectivity in overlap of chronic facial and bodily pain | Gary D. Slade (+9) | 2019 | PAIN Reports |
4318 | Asthma and affective traits in adults: a genetically informative study | Lehto K et al. | 2019 | Eur Respir J |
4342 | BGData - A Suite of R Packages for Genomic Analysis with Big Data | Alexander Grueneberg (+1) | 2019 | G3: Genes, Genomes, Genetics |
4530 | Coffee consumption by type and risk of digestive cancer: a large prospective cohort study | Tran KT et al. | 2019 | Br J Cancer |
5895 | The spatial correspondence and genetic influence of interhemispheric connectivity with white matter microstructure | Mollink J et al. | 2019 | Nat Neurosci |
4016 | Age-Related Differences in Brain Morphology and the Modifiers in Middle-Aged and Older Adults | Lu Zhao (+5) | 2019 | Cerebral Cortex |
2770 | Poorer Speech Reception Threshold in Noise Is Associated With Lower Brain Volume in Auditory and Cognitive Processing Regions | Rudner M et al. | 2019 | J Speech Lang Hear Res |
2853 | Reflection on modern methods: calculating a sample size for a repeatability sub-study to correct for measurement error in a single continuous exposure | Katy E Morgan (+3) | 2019 | International Journal of Epidemiology |
3453 | Genome-wide association study of medication-use and associated disease in the UK Biobank | Wu Y et al. | 2019 | Nat Commun |
5977 | Validation of concurrent preimplantation genetic testing for polygenic and monogenic disorders, structural rearrangements, and whole and segmental chromosome aneuploidy with a single universal platform | Nathan R Treff (+16) | 2019 | European Journal of Medical Genetics |
4335 | Automatic CNN-based detection of cardiac MR motion artefacts using k-space data augmentation and curriculum learning | Ilkay Oksuz (+10) | 2019 | Medical Image Analysis |
2830 | Body composition and atrial fibrillation: a Mendelian randomization study | Tikkanen E et al. | 2019 | Eur Heart J |
3183 | Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity | Lotta LA et al. | 2019 | Cell |
7332 | Polygenic prediction via Bayesian regression and continuous shrinkage priors | Tian Ge (+4) | 2019 | Nature Communications |
2896 | The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study | Taylor AE et al. | 2019 | Hum Mol Genet |
7328 | Predictive Big Data Analytics using the UK Biobank Data | Yiwang Zhou (+8) | 2019 | Scientific Reports |
7662 | The molecular genetics of hand preference revisited | Carolien G. F. de Kovel (+1) | 2019 | Scientific Reports |
2836 | Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort | Jani BD et al. | 2019 | BMC Med |
7327 | Selection Bias When Estimating Average Treatment Effects Using One-sample Instrumental Variable Analysis | Rachael A. Hughes (+3) | 2019 | Epidemiology |
7663 | Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis | Zhaozhong Zhu (+12) | 2019 | Respiratory Research |
2145 | Polygenic Risk Score Is Associated With Intraocular Pressure and Improves Glaucoma Prediction in the UK Biobank Cohort | Gao XR et al. | 2019 | Transl Vis Sci Technol |
3088 | Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort | Gao XR et al. | 2019 | Hum Mol Genet |
3856 | A Candidate-Gene Approach Identifies Novel Associations Between Common Variants in/Near Syndromic Obesity Genes and BMI in Pediatric and Adult European Populations | Wang DX et al. | 2019 | Diabetes |
4111 | Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study | Choi KW et al. | 2019 | JAMA Psychiatry |
4153 | Association between musculoskeletal pain at multiple sites and objectively measured physical activity and work capacity: Results from UK Biobank study | Pan F et al. | 2019 | J Sci Med Sport |
4170 | Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents: A Voxelwise and Genome-Wide Association Study | Luo Q et al. | 2019 | JAMA Psychiatry |
4580 | Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals: a systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies | Smith T et al. | 2019 | Gut |
4889 | Genetic and observational evidence supports a causal role of sex hormones on the development of asthma | Ryan Arathimos (+6) | 2019 | Thorax |
5237 | Inferring Multidimensional Rates of Aging from Cross-Sectional Data | Pierson E et al. | 2019 | Proc Mach Learn Res |
5708 | Sequence variants associating with urinary biomarkers | Benonisdottir S et al. | 2019 | Hum Mol Genet |
5367 | Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease | Marouli E et al. | 2019 | Commun Biol |
5512 | Parent of origin genetic effects on methylation in humans are common and influence complex trait variation | Zeng Y et al. | 2019 | Nat Commun |
7514 | Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches | Stephen F. Weng (+3) | 2019 | PLOS ONE |
4381 | Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses | Sun YQ et al. | 2019 | BMJ |
7515 | Mood Instability and Trait Anxiety as Distinct Components of Eysenckian Neuroticism With Differential Relations to Impulsivity and Risk Taking | Evyn M. Peters (+2) | 2019 | Journal of Personality Assessment |
5653 | Reduced signal for polygenic adaptation of height in UK Biobank | Jeremy J Berg (+10) | 2019 | eLife |
5994 | Vitamin D levels and risk of delirium: A mendelian randomization study in the UK Biobank | Bowman K et al. | 2019 | Neurology |
4000 | Age and cognitive decline in the UK Biobank | Marilyn C. Cornelis (+5) | 2019 | PLOS ONE |
5930 | Type 2 Diabetes and Hypertension | Sun D et al. | 2019 | Circ Res |
7323 | Potential influence of socioeconomic status on genetic correlations between alcohol consumption measures and mental health | Andries T. Marees (+8) | 2019 | Psychological Medicine |
2742 | A Frailty Index for UK Biobank Participants | Williams DM et al. | 2019 | J Gerontol A Biol Sci Med Sci |
4330 | Automated quality control in image segmentation: application to the UK Biobank cardiovascular magnetic resonance imaging study | Robert Robinson (+21) | 2019 | Journal of Cardiovascular Magnetic Resonance |
7516 | No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples | Richard Border (+6) | 2019 | American Journal of Psychiatry |
2152 | Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank | Luo S et al. | 2019 | BMJ |
4044 | An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome | Richardson TG et al. | 2019 | Elife |
7517 | Assessing the causal association of glycine with risk of cardio-metabolic diseases | Laura B. L. Wittemans (+22) | 2019 | Nature Communications |
3881 | A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome | Wiberg A et al. | 2019 | Nat Commun |
1702 | Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank | Crawford K et al. | 2019 | J Med Genet |
1944 | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries | Shrine N et al. | 2019 | Nat Genet |
2525 | Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide | Strawbridge RJ et al. | 2019 | EBioMedicine |
2661 | Premenopausal cardiovascular disease and age at natural menopause: a pooled analysis of over 170,000 women | Zhu D et al. | 2019 | Eur J Epidemiol |
2711 | Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk | Jansen IE et al. | 2019 | Nat Genet |
2714 | Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study | Olivo G et al. | 2019 | Psychoneuroendocrinology |
2748 | Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations | Sakornsakolpat P et al. | 2019 | Nat Genet |
2758 | Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases | Zhou A et al. | 2019 | Am J Clin Nutr |
3124 | eQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data | Le Guen Y et al. | 2019 | Brain Struct Funct |
4096 | Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals | Garfield V et al. | 2019 | Genet Epidemiol |
4288 | Associations of dietary protein intake with bone mineral density: An observational study in 70,215 UK Biobank participants | Steell L et al. | 2019 | Bone |
4517 | Clinical Utility and Practical Considerations of a Coronary Artery Disease Genetic Risk Score | Liu R et al. | 2019 | CJC Open |
4999 | Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways | Jansen PR et al. | 2019 | Nat Genet |
7345 | Walking Pace Is Associated with Lower Risk of All-Cause and Cause-Specific Mortality | Carlos A Celis-Morales (+11) | 2019 | Medicine & Science in Sports & Exercise |
4011 | Age-dependent co-dependency structure of biomarkers in the general population of the United States | Alan Le Goallec (+1) | 2019 | Aging |
7348 | Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization | David M Evans (+4) | 2019 | International Journal of Epidemiology |
4488 | Chronotype, depression and hippocampal volume: cross-sectional associations from the UK Biobank | Ray Norbury | 2019 | Chronobiology International |
4543 | Cohort profile: design and methods in the eye and vision consortium of UK Biobank | Chua SYL et al. | 2019 | BMJ Open |
1624 | Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts | Atkins JL et al. | 2019 | J Gerontol A Biol Sci Med Sci |
4540 | Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank | Kimberley M. Kendall (+9) | 2019 | The British Journal of Psychiatry |
1972 | Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data | Biasiolli L et al. | 2019 | PLoS One |
7441 | RE: "ASSOCIATIONS OF DIETARY PROTEIN INTAKE WITH FAT-FREE MASS AND GRIP STRENGTH: A CROSS-SECTIONAL STUDY IN 146,816 UK BIOBANK PARTICIPANTS". | Tammy Y N Tong (+2) | 2019 | American Journal of Epidemiology |
3923 | A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR | Safarova MS et al. | 2019 | NPJ Genom Med |
4104 | Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting | Wright CF et al. | 2019 | Am J Hum Genet |
3210 | Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals | Maxim B Freidin (+6) | 2019 | Pain |
3077 | Physical activity of UK adults with chronic disease: cross-sectional analysis of accelerometer-measured physical activity in 96 706 UK Biobank participants | Joseph Barker (+7) | 2019 | International Journal of Epidemiology |
4176 | Association of body mass index and waist-to-hip ratio with brain structure: UK Biobank study | Hamer M et al. | 2019 | Neurology |
2837 | Cognitive ability and risk of death from lower respiratory tract infection: findings from UK Biobank | Catharine R. Gale (+2) | 2019 | Scientific Reports |
3050 | Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions | David M. Howard (+37) | 2019 | Nature Neuroscience |
3562 | Independent Left Ventricular Morphometric Atlases Show Consistent Relationships with Cardiovascular Risk Factors: A UK Biobank Study | Gilbert K et al. | 2019 | Sci Rep |
5055 | Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland | Arnau-Soler A et al. | 2019 | Transl Psychiatry |
7664 | Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes | Wonil Chung (+7) | 2019 | Nature Communications |
2160 | Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences | Karlsson Linnér R et al. | 2019 | Nat Genet |
2693 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Liu M et al. | 2019 | Nat Genet |
2706 | Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis | Skaaby T et al. | 2019 | Addiction |
2807 | Muscle mass measures and incident osteoporosis in a large cohort of postmenopausal women | Papageorgiou M et al. | 2019 | J Cachexia Sarcopenia Muscle |
3051 | Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts | Sanchez-Roige S et al. | 2019 | Am J Psychiatry |
3858 | A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence | Hill WD et al. | 2019 | Mol Psychiatry |
3885 | A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia | Huang Y et al. | 2019 | Invest Ophthalmol Vis Sci |
3908 | A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis | Kristjansson RP et al. | 2019 | Nat Genet |
4426 | Cardiovascular Risk Factors Associated With Venous Thromboembolism | Gregson J et al. | 2019 | JAMA Cardiol |
4663 | Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis | Sharp SA et al. | 2019 | Diabetes Care |
4708 | Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease | Broce IJ et al. | 2019 | Acta Neuropathol |
7340 | Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization | Louise A. C. Millard (+4) | 2019 | PLOS Genetics |
1828 | Identification of 12 genetic loci associated with human healthspan | Aleksandr Zenin (+6) | 2019 | Communications Biology |
1863 | Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms | Jones SE et al. | 2019 | Nat Commun |
3964 | Accelerometer compared with questionnaire measures of physical activity in relation to body size and composition: a large cross-sectional analysis of UK Biobank | Guo W et al. | 2019 | BMJ Open |
3652 | A large-scale population study of early life factors influencing left-handedness | Carolien G. F. de Kovel (+2) | 2019 | Scientific Reports |
7518 | Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank | Anthony Warland (+4) | 2019 | Molecular Psychiatry |
5252 | Integrating predicted transcriptome from multiple tissues improves association detection | Alvaro N. Barbeira (+5) | 2019 | PLOS Genetics |
4082 | Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis | Simon Haworth (+12) | 2019 | Nature Communications |
7443 | A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect | Katerina Zorina-Lichtenwalter (+6) | 2019 | Human Molecular Genetics |
2895 | Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances | Timmers PR et al. | 2019 | Elife |
5034 | Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection | Takeuchi F et al. | 2019 | Hum Mol Genet |
2745 | The effect of personalised weight feedback on weight loss and health behaviours: Evidence from a regression discontinuity design | Cook W | 2019 | Health Econ |
2805 | Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry | Pulit SL et al. | 2019 | Hum Mol Genet |
3141 | Discovery of common and rare genetic risk variants for colorectal cancer | Huyghe JR et al. | 2019 | Nat Genet |
3907 | A linear mixed-model approach to study multivariate gene-environment interactions | Moore R et al. | 2019 | Nat Genet |
4187 | Association of DAT1 genetic variants with habitual sleep duration in the UK Biobank | Rhodes JA et al. | 2019 | Sleep |
4244 | Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank | Barbu MC et al. | 2019 | Biol Psychiatry Cogn Neurosci Neuroimaging |
4473 | Characteristics of the environment and physical activity in midlife: Findings from UK Biobank | Smith L et al. | 2019 | Prev Med |
4503 | Circulating Phylloquinone Concentrations and Risk of Type 2 Diabetes: A Mendelian Randomization Study | Zwakenberg SR et al. | 2019 | Diabetes |
4609 | Correlates of Hearing Aid Use in UK Adults | Chelsea S. Sawyer (+4) | 2019 | Ear & Hearing |
4716 | DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes | Emdin CA et al. | 2019 | Diabetes |
4815 | Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study | Budu-Aggrey A et al. | 2019 | PLoS Med |
5001 | Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension | Ji Y et al. | 2019 | Diabetes |
5122 | Hearing Difficulties and Tinnitus in Construction, Agricultural, Music, and Finance Industries: Contributions of Demographic, Health, and Lifestyle Factors | Samuel Couth (+4) | 2019 | Trends in Hearing |
5918 | Trans-ethnic association study of blood pressure determinants in over 750,000 individuals | Giri A et al. | 2019 | Nat Genet |