| Pub ID | Title | Author(s) | Year | Journal |
|---|
| 3135 | Systematic drug repurposing to enable precision medicine: A case study in breast cancer | Taylor et al. | 2019 | Digital Medicine (2019) |
| 5457 | Emergency personnel neuroticism, health and lifestyle: A UK Biobank study | M Mutambudzi (+2) | 2019 | Occupational Medicine |
| 5694 | Sarcopenia, long-term conditions, and multimorbidity: findings from UK Biobank participants | Richard M. Dodds (+3) | 2019 | Journal of Cachexia Sarcopenia and Muscle |
| 5200 | Impact of glycemic traits, type 2 diabetes and metformin use on breast and prostate cancer risk: a Mendelian randomization study | Au Yeung SL et al. | 2019 | BMJ Open Diabetes Res Care |
| 5493 | Objective sleep assessment in >80,000 UK mid-life adults: Associations with sociodemographic characteristics, physical activity and caffeine | Gewei Zhu (+7) | 2019 | PLOS ONE |
| 5506 | Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale | Christopher A. German (+4) | 2019 | Genetic Epidemiology |
| 5828 | The circadian clock protein REVERBα inhibits pulmonary fibrosis development | Peter S. Cunningham (+23) | 2019 | Proceedings of the National Academy of Sciences of the United States of America |
| 5763 | Smoking, blood cells and myeloproliferative neoplasms: meta-analysis and Mendelian randomization of 2·3 million people | Nimesh A. Jayasuriya (+13) | 2019 | British Journal of Haematology |
| 4224 | Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease | Honigberg MC et al. | 2019 | JAMA |
| 5036 | Genome-wide association study of cognitive performance in U.S. veterans with schizophrenia or bipolar disorder | Philip D. Harvey (+29) | 2019 | American Journal of Medical Genetics Part B Neuropsychiatric Genetics |
| 3657 | Detection of anaemia from retinal fundus images via deep learning | Akinori Mitani (+8) | 2019 | Nature Biomedical Engineering |
| 5178 | Identifying cross-disease components of genetic risk across hospital data in the UK Biobank | Adrian Cortes (+4) | 2019 | Nature Genetics |
| 5470 | No statistical evidence for an effect of CCR5-∆32 on lifespan in the UK Biobank cohort | Robert Maier (+5) | 2019 | Nature Medicine |
| 5954 | Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations | Madeline H. Kowalski (+77) | 2019 | PLOS Genetics |
| 2385 | Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke | Gad Abraham (+9) | 2019 | Nature Communications |
| 5703 | Selective peak inference: Unbiased estimation of raw and standardized effect size at local maxima | Samuel Davenport (+1) | 2019 | NeuroImage |
| 5847 | The emerging landscape of health research based on biobanks linked to electronic health records: Existing resources, statistical challenges, and potential opportunities | Lauren J. Beesley (+8) | 2019 | Statistics in Medicine |
| 4315 | Associations with photoreceptor thickness measures in the UK Biobank | Sharon Y. L. Chua (+9) | 2019 | Scientific Reports |
| 5358 | Maternal smoking, genetic susceptibility, and birth-to-adulthood body weight | Dianjianyi Sun (+5) | 2019 | International Journal of Obesity |
| 5934 | UK Biobank Whole-Exome Sequence Binary Phenome Analysis with Robust Region-Based Rare-Variant Test | Zhangchen Zhao (+5) | 2019 | American Journal of Human Genetics |
| 7639 | Genotype-free demultiplexing of pooled single-cell RNA-seq | Jun Xu (+17) | 2019 | Genome Biology |
| 2844 | Association Between Recreational Cannabis Use and Cardiac Structure and Function | Mohammed Y Khanji (+15) | 2019 | JACC Cardiovascular Imaging |
| 3672 | Glycated Hemoglobin, Prediabetes, and the Links to Cardiovascular Disease: Data From UK Biobank | Claire Welsh (+18) | 2019 | Diabetes Care |
| 5754 | Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants | Mengyu Fan (+6) | 2019 | European Heart Journal |
| 9088 | Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent | Christopher Hübel (+11) | 2019 | Nature Communications |
| 4601 | Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study | Mirthe Muilwijk (+14) | 2019 | BMJ Open Diabetes Research & Care |
| 4994 | Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income | W. David Hill (+16) | 2019 | Nature Communications |
| 5619 | Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health | Qian Yang (+2) | 2019 | International Journal of Epidemiology |
| 6003 | White blood cell count and risk of incident lung cancer in the UK Biobank | Jason Y Y Wong (+10) | 2019 | JNCI Cancer Spectrum |
| 5485 | Nucleus accumbens volume is related to obesity measures in an age-dependent fashion | Isabel García-García (+2) | 2019 | Journal of Neuroendocrinology |
| 5680 | Risk factors for ductal carcinoma in situ of the breast in the UK Biobank cohort study | Rita Peila (+2) | 2019 | Cancer Epidemiology |
| 7325 | Detangling red hair from pain: phenotype-specific contributions from different genetic variants in melanocortin-1 receptor. | Katerina Zorina-Lichtenwalter (+2) | 2019 | Pain |
| 9087 | Hormone-related diseases and prostate cancer: An English national record linkage study | Eleanor L. Watts (+5) | 2019 | International Journal of Cancer |
| 5241 | Insights into the genetic basis of retinal detachment | Thibaud S Boutin (+40) | 2019 | Human Molecular Genetics |
| 9086 | Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan | Raymond Pomponio (+29) | 2019 | NeuroImage |
| 3379 | Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure | Joey Ward (+11) | 2019 | Translational Psychiatry |
| 4850 | Familial Influences on Neuroticism and Education in the UK Biobank | R. Cheesman (+8) | 2019 | Behavior Genetics |
| 7324 | Utility and First Clinical Application of Screening Embryos for Polygenic Disease Risk Reduction | Nathan R. Treff (+10) | 2019 | Frontiers in Endocrinology |
| 9085 | The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain | Robert Fredriksson (+22) | 2019 | PLOS Genetics |
| 3209 | ISSLS Prize in Clinical Science 2020. Examining causal effects of body mass index on back pain: a Mendelian randomization study | Elizaveta E. Elgaeva (+5) | 2019 | European Spine Journal |
| 4303 | Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance | Suzuki H et al. | 2019 | JAMA Netw Open |
| 5325 | LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels | Jaakko T. Leinonen (+7) | 2019 | Scientific Reports |
| 3273 | Deep Learning and Glaucoma Specialists: The Relative Importance of Optic Disc Features to Predict Glaucoma Referral in Fundus Photographs | Phene S et al. | 2019 | Ophthalmology |
| 3631 | Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies | Mike A Nalls (+272) | 2019 | The Lancet Neurology |
| 4052 | Integrated Multiomics Approach to Identify Genetic Underpinnings of Heart Failure and Its Echocardiographic Precursors: Framingham Heart Study | Andersson C et al. | 2019 | Circ Genom Precis Med |
| 4194 | Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits | Legge SE et al. | 2019 | JAMA Psychiatry |
| 4306 | Associations of Retinal Microvascular Diameters and Tortuosity With Blood Pressure and Arterial Stiffness: United Kingdom Biobank | Tapp RJ et al. | 2019 | Hypertension |
| 4912 | Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation | Allara E et al. | 2019 | Circ Genom Precis Med |
| 5145 | Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study | Wainberg M et al. | 2019 | PLoS Med |
| 5590 | Predicting incident dementia 3-8 years after brief cognitive tests in the UK Biobank prospective study of 500,000 people | Calvin CM et al. | 2019 | Alzheimers Dement |
| 5976 | Validation of Cardiovascular Magnetic Resonance-Derived Equation for Predicted Left Ventricular Mass Using the UK Biobank Imaging Cohort: Tool for Donor-Recipient Size Matching | Fung K et al. | 2019 | Circ Heart Fail |
| 5269 | Investigating Causality Between Blood Metabolites and Emotional and Behavioral Responses to Traumatic Stress: a Mendelian Randomization Study | Carolina Muniz Carvalho (+6) | 2019 | Molecular Neurobiology |
| 3634 | Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment | Amaia Carrion-Castillo (+7) | 2019 | Cortex |
| 4237 | Association of supplemental calcium and dairy milk intake with all-cause and cause-specific mortality in the UK Biobank: a prospective cohort study | L. C. Stasinopoulos (+2) | 2019 | British Journal Of Nutrition |
| 7507 | Mapping ICD-10 and ICD-10-CM Codes to Phecodes: Workflow Development and Initial Evaluation | Patrick Wu (+11) | 2019 | JMIR Medical Informatics |
| 3976 | Accurate, scalable and integrative haplotype estimation | Olivier Delaneau (+4) | 2019 | Nature Communications |
| 2283 | Brain age prediction using deep learning uncovers associated sequence variants | B. A. Jonsson (+8) | 2019 | Nature Communications |
| 5442 | Multi-trait genome-wide association study identifies new loci associated with optic disc parameters | Bonnemaijer PWM et al. | 2019 | Commun Biol |
| 5206 | Impact of Rheumatoid Arthritis and Its Management on Falls, Fracture and Bone Mineral Density in UK Biobank | Michael A. Clynes (+5) | 2019 | Frontiers in Endocrinology |
| 3678 | A resource-efficient tool for mixed model association analysis of large-scale data | Longda Jiang (+6) | 2019 | Nature Genetics |
| 4747 | Educational attainment and drinking behaviors: Mendelian randomization study in UK Biobank | Tao Zhou (+5) | 2019 | Molecular Psychiatry |
| 5881 | The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM2.5) and Glaucoma in a Large Community Cohort | Sharon Y. L. Chua (+8) | 2019 | Investigative Ophthalmology & Visual Science |
| 4114 | Assessment of MTNR1B Type 2 Diabetes Genetic Risk Modification by Shift Work and Morningness-Eveningness Preference in the UK Biobank | Hassan S. Dashti (+9) | 2019 | Diabetes |
| 5887 | The role of haematological traits in risk of ischaemic stroke and its subtypes | Eric L Harshfield (+4) | 2019 | Brain |
| 9084 | Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia | Cornelis Blauwendraat (+62) | 2019 | Brain |
| 5054 | Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2 | Ana I Hernandez Cordero (+11) | 2019 | American Journal of Human Genetics |
| 5353 | Making the Most of Clumping and Thresholding for Polygenic Scores | Florian Privé (+3) | 2019 | American Journal of Human Genetics |
| 4931 | Genetic predisposition to mosaic Y chromosome loss in blood | Deborah J. Thompson (+50) | 2019 | Nature |
| 7508 | Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5 | Keira J. A. Johnston (+7) | 2019 | Translational Psychiatry |
| 9053 | A major role for common genetic variation in anxiety disorders | Kirstin L. Purves (+25) | 2019 | Molecular Psychiatry |
| 1743 | Genetic evidence for assortative mating on alcohol consumption in the UK Biobank | Laurence J. Howe (+6) | 2019 | Nature Communications |
| 2636 | Depressive symptoms, neuroticism, and participation in breast and cervical cancer screening: Cross-sectional and prospective evidence from UK Biobank | Claire L. Niedzwiedz (+4) | 2019 | Psycho-Oncology |
| 5706 | Self-reported sleep relates to hippocampal atrophy across the adult lifespan: results from the Lifebrain consortium | Anders M Fjell (+27) | 2019 | Sleep |
| 5463 | New versus old guidelines for sarcopenia classification: What is the impact on prevalence and health outcomes? | Fanny Petermann-Rocha (+5) | 2019 | Age and Ageing |
| 6006 | White Matter Microstructure and Its Relation to Longitudinal Measures of Depressive Symptoms in Mid- and Late Life | Shen X et al. | 2019 | Biol Psychiatry |
| 6013 | Whole-Genome Sequencing of Childhood Cancer Survivors Treated with Cranial Radiation Therapy Identifies 5p15.33 Locus for Stroke: A Report from the St. Jude Lifetime Cohort Study | Yadav Sapkota (+12) | 2019 | Clinical Cancer Research |
| 3868 | A Fast and Accurate Method for Genome-wide Scale Phenome-wide G × E Analysis and Its Application to UK Biobank | Wenjian Bi (+5) | 2019 | American Journal of Human Genetics |
| 5260 | Interaction effect of alcohol consumption and Alzheimer disease polygenic risk score on the brain cortical thickness of cognitively normal subjects | William J Matloff (+4) | 2019 | Alcohol |
| 9049 | Establishing the variation of blood metrics within UK Biobank to inform cell therapy manufacturing processes | Jamie Thurman-Newell (+2) | 2019 | Regenerative Medicine |
| 4725 | Does a physically active lifestyle attenuate the association between alcohol consumption and mortality risk? Findings from the UK biobank | Lauren Powell (+4) | 2019 | Preventive Medicine |
| 5417 | Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle: A UK Biobank study | Francesco Zaccardi (+5) | 2019 | European Journal of Preventive Cardiology |
| 3873 | A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients. | Rodrigo Benavides (+9) | 2019 | Pain |
| 4165 | Association between the 4p16 genomic locus and different types of congenital heart disease: results from adult survivors in the UK Biobank | Aldo Córdova-Palomera (+1) | 2019 | Scientific Reports |
| 5337 | Long-Term Cardiovascular Risk in Women With Hypertension During Pregnancy | Michael C Honigberg (+7) | 2019 | Journal of the American College of Cardiology |
| 4130 | Association between cardiorespiratory fitness and colorectal cancer in the UK Biobank | Andrea Hillreiner (+5) | 2019 | European Journal of Epidemiology |
| 3256 | Improved polygenic prediction by Bayesian multiple regression on summary statistics | Luke R. Lloyd-Jones (+14) | 2019 | Nature Communications |
| 3639 | Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease | Jennifer S. Lees (+13) | 2019 | Nature Medicine |
| 4961 | Genetically Determined Physical Activity and Its Association with Circulating Blood Cells | Femke M Prins (+5) | 2019 | Genes |
| 12908 | Handgrip Strength Is Associated With Hippocampal Volume and White Matter Hyperintensities in Major Depression and Healthy Controls: A UK Biobank Study. | Josh A Firth (+9) | 2019 | Psychosomatic Medicine |
| 4755 | Effects of blood lead on coronary artery disease and its risk factors: a Mendelian Randomization study | C. Mary Schooling (+2) | 2019 | Scientific Reports |
| 2659 | Age at natural menopause and risk of incident cardiovascular disease: a pooled analysis of individual patient data | Zhu D et al. | 2019 | Lancet Public Health |
| 3422 | Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits | Bingxin Zhao (+10) | 2019 | Nature Genetics |
| 4017 | Aging-related changes in fluid intelligence, muscle and adipose mass, and sex-specific immunologic mediation: A longitudinal UK Biobank study | Klinedinst BS et al. | 2019 | Brain Behav Immun |
| 4192 | Association of Fitness and Grip Strength With Heart Failure Findings From the UK Biobank Population-Based Study | Anne Sillars (+15) | 2019 | Mayo Clinic Proceedings |
| 4313 | Associations with Corneal Hysteresis in a Population Cohort: Results from 96 010 UK Biobank Participants | Zhang B et al. | 2019 | Ophthalmology |
| 4432 | Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy | Czesnikiewicz-Guzik M et al. | 2019 | Eur Heart J |
| 4779 | Environmental correlates of chronic obstructive pulmonary disease in 96 779 participants from the UK Biobank: a cross-sectional, observational study | Sarkar C et al. | 2019 | Lancet Planet Health |
| 5011 | Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease | Derek Klarin (+41) | 2019 | Nature Genetics |
| 5156 | Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis | Eales JM et al. | 2019 | Arterioscler Thromb Vasc Biol |
| 5808 | The association between self-reported poor oral health and gastrointestinal cancer risk in the UK Biobank: A large prospective cohort study | Jordão HW et al. | 2019 | United European Gastroenterol J |
| 4278 | Associations of autozygosity with a broad range of human phenotypes | David W Clark (+435) | 2019 | Nature Communications |
| 5421 | MR-pheWAS with stratification and interaction: Searching for the causal effects of smoking heaviness identified an effect on facial aging | Louise A. C. Millard (+4) | 2019 | PLOS Genetics |
| 3073 | Identifying Morphological Indicators of Aging With Neural Networks on Large-Scale Whole-Body MRI | Taro Langner (+4) | 2019 | IEEE Transactions on Medical Imaging |
| 3421 | Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n = 17,706) | Bingxin Zhao (+12) | 2019 | Molecular Psychiatry |
| 9046 | Associations of Retinal Microvascular Diameters and Tortuosity With Blood Pressure and Arterial Stiffness | Robyn J. Tapp (+8) | 2019 | Hypertension |
| 4482 | Childhood trauma, life-time self-harm, and suicidal behaviour and ideation are associated with polygenic scores for autism | Varun Warrier (+1) | 2019 | Molecular Psychiatry |
| 4908 | Genetic correlations between pain phenotypes and depression and neuroticism | Weihua Meng (+8) | 2019 | European Journal of Human Genetics |
| 5003 | Genome-Wide Assessment for Resting Heart Rate and Shared Genetics With Cardiometabolic Traits and Type 2 Diabetes | Guo Y et al. | 2019 | J Am Coll Cardiol |
| 5671 | Reproducibility of dietary intakes of macronutrients, specific food groups, and dietary patterns in 211 050 adults in the UK Biobank study | Jennifer L. Carter (+8) | 2019 | Journal of Nutritional Science |
| 4855 | Female reproductive history in relation to chronic obstructive pulmonary disease and lung function in UK biobank: a prospective population-based cohort study | Tang R et al. | 2019 | BMJ Open |
| 3460 | Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer | Louis Lello (+4) | 2019 | Scientific Reports |
| 2712 | Genetic mapping and evolutionary analysis of human-expanded cognitive networks | Wei Y et al. | 2019 | Nat Commun |
| 4459 | Causal relationships between obesity and the leading causes of death in women and men | Jenny C. Censin (+8) | 2019 | PLOS Genetics |
| 5862 | The Human-Specific BOLA2 Duplication Modifies Iron Homeostasis and Anemia Predisposition in Chromosome 16p11.2 Autism Individuals | Giuliana Giannuzzi (+21) | 2019 | American Journal of Human Genetics |
| 9045 | Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis | C. S. Gallagher (+35) | 2019 | Nature Communications |
| 4732 | Does self-reported pregnancy loss identify women at risk of an adverse cardiovascular phenotype in later life? Insights from UK Biobank | Einas Elmahi (+12) | 2019 | PLOS ONE |
| 5499 | On the Definition of Sarcopenia in the Presence of Aging and Obesity-Initial Results from UK Biobank | Jennifer Linge (+2) | 2019 | The Journals of Gerontology Series A |
| 5964 | Using instrumental variables to estimate the attributable fraction | Elisabeth Dahlqwist (+2) | 2019 | Statistical Methods in Medical Research |
| 7341 | A Spatio-Temporal Ageing Atlas of the Proximal Femur | Mohsen Farzi (+6) | 2019 | IEEE Transactions on Medical Imaging |
| 8199 | Birth Weight and Development: Bias or Heterogeneity by Polygenic Risk Factors? | Dalton Conley (+2) | 2019 | Population Research and Policy Review |
| 3470 | Comparison of accelerometer-derived physical activity levels between individuals with and without cancer: a UK Biobank study | Laura McDonald (+10) | 2019 | Future Oncology |
| 9044 | Sequence variants with large effects on cardiac electrophysiology and disease | Kristjan Norland (+22) | 2019 | Nature Communications |
| 4894 | Genetic architecture of subcortical brain structures in 38,851 individuals | Claudia L. Satizabal (+288) | 2019 | Nature Genetics |
| 4904 | Genetic correlates of social stratification in Great Britain | Abdel Abdellaoui (+12) | 2019 | Nature Human Behaviour |
| 3887 | A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio | Francesco Casanova (+10) | 2019 | Human Molecular Genetics |
| 3501 | External Replication of Urinary Bladder Cancer Prognostic Polymorphisms in the UK Biobank | Nadezda Lipunova (+6) | 2019 | Frontiers in Oncology |
| 4823 | Exome Sequencing in BRCA1- and BRCA2-Negative Greek Families Identifies MDM1 and NBEAL1 as Candidate Risk Genes for Hereditary Breast Cancer | Glentis S et al. | 2019 | Front Genet |
| 5395 | Metabolites downstream of predicted loss-of-function variants inform relationship to disease | Mengbo Li (+6) | 2019 | Molecular Genetics and Metabolism |
| 9043 | GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation | Chikashi Terao (+14) | 2019 | Nature Communications |
| 5742 | Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis | Zhaozhong Zhu (+8) | 2019 | European Respiratory Journal |
| 5000 | Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development | Aung N et al. | 2019 | Circulation |
| 5586 | Population-based neuroimaging reveals traces of childbirth in the maternal brain | Ann-Marie G. de Lange (+8) | 2019 | Proceedings of the National Academy of Sciences of the United States of America |
| 4644 | Depression increases the genetic susceptibility to high body mass index: Evidence from UK Biobank | Anwar Mulugeta (+4) | 2019 | Depression and Anxiety |
| 5564 | Polygenic burden in focal and generalized epilepsies | Costin Leu (+20) | 2019 | Brain |
| 4638 | Deep neural networks and kernel regression achieve comparable accuracies for functional connectivity prediction of behavior and demographics | Tong He (+8) | 2019 | NeuroImage |
| 4967 | Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank | Kathryn Demanelis (+2) | 2019 | The Journals of Gerontology Series A |
| 12909 | Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability | Bryce van de Geijn (+11) | 2019 | Human Molecular Genetics |
| 4196 | Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease | Ference BA et al. | 2019 | JAMA |
| 7509 | Genetic contributions to variation in human stature in prehistoric Europe | Samantha L. Cox (+3) | 2019 | Proceedings of the National Academy of Sciences of the United States of America |
| 9042 | International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci | Caroline M. Nievergelt (+178) | 2019 | Nature Communications |
| 5051 | Genome-Wide Association Study of the Metabolic Syndrome in UK Biobank | Lars Lind | 2019 | Metabolic Syndrome and Related Disorders |
| 5746 | Shift Workers Have Higher Blood Pressure Medicine Use, But Only When They Are Short Sleepers: A Longitudinal UK Biobank Study | Barbara Riegel (+5) | 2019 | Journal of the American Heart Association |
| 2823 | Cigarette smoking and personality: interrogating causality using Mendelian randomisation | Sallis HM et al. | 2019 | Psychol Med |
| 3099 | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels | Tin A et al. | 2019 | Nat Genet |
| 3113 | Common brain disorders are associated with heritable patterns of apparent aging of the brain | Kaufmann T et al. | 2019 | Nat Neurosci |
| 4423 | Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics | Ramírez J et al. | 2019 | Circ Arrhythm Electrophysiol |
| 4449 | Causal Factors for Knee, Hip, and Hand Osteoarthritis: A Mendelian Randomization Study in the UK Biobank | Funck-Brentano T et al. | 2019 | Arthritis Rheumatol |
| 4896 | Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis | Thériault S et al. | 2019 | Circ Genom Precis Med |
| 4907 | Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes | Laville V et al. | 2019 | Am J Ophthalmol |
| 4963 | Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study | Li X et al. | 2019 | PLoS Med |
| 5533 | Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study | Meng X et al. | 2019 | Int J Epidemiol |
| 5547 | Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank | Folley S et al. | 2019 | J Alzheimers Dis |
| 5959 | Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight | Hwang LD et al. | 2019 | Int J Epidemiol |
| 7377 | 52 A PHENOME-WIDE ASSOCIATION AND MENDELIAN RANDOMISATION STUDY OF POLYGENIC RISK FOR DEPRESSION IN UK BIOBANK | Xueyi Shen (+7) | 2019 | European Neuropsychopharmacology |
| 2831 | Impact of major depression on cardiovascular outcomes for individuals with hypertension: prospective survival analysis in UK Biobank | Nicholas Graham (+6) | 2019 | BMJ Open |
| 4630 | Deconstructing the sources of genotype-phenotype associations in humans | Alexander I Young (+3) | 2019 | Science |
| 9041 | Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI | Benjamin Georgi (+10) | 2019 | Stroke |
| 3084 | GWAS Identifies 44 Independent Associated Genomic Loci for Self-Reported Adult Hearing Difficulty in UK Biobank | Helena R R Wells (+9) | 2019 | American Journal of Human Genetics |
| 5204 | Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program | Chloé Sarnowski (+45) | 2019 | American Journal of Human Genetics |
| 8898 | Genetic architecture of human plasma lipidome and its link to cardiovascular disease | Rubina Tabassum (+27) | 2019 | Nature Communications |
| 7640 | A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity | Mickael Rosa (+7) | 2019 | npj Genomic Medicine |
| 2859 | The association between driving time and unhealthy lifestyles: a cross-sectional, general population study of 386 493 UK Biobank participants | A Mackay (+8) | 2019 | Journal of Public Health |
| 4865 | Frequency and distribution of corneal astigmatism and keratometry features in adult life: Methodology and findings of the UK Biobank study | Nikolas Pontikos (+5) | 2019 | PLOS ONE |
| 4919 | Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9 | Jackson G. Thorp (+5) | 2019 | Psychological Medicine |
| 1763 | Multivariable two-sample Mendelian randomization estimates of the effects of intelligence and education on health | Neil Martin Davies (+5) | 2019 | eLife |
| 5201 | Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study | Emanuelsson F et al. | 2019 | J Am Coll Cardiol |
| 3939 | A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD-Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis | Celia L Gregson (+21) | 2019 | Journal of Bone and Mineral Research |
| 8897 | Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases | Jiyuan An (+17) | 2019 | Nature Communications |
| 7660 | Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness | Abdel Abdellaoui (+28) | 2019 | Human Molecular Genetics |
| 3098 | Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria | Alexander Teumer (+185) | 2019 | Nature Communications |
| 4600 | Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease | Torgny Karlsson (+6) | 2019 | Nature Medicine |
| 4586 | Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology | Yosuke Tanigawa (+13) | 2019 | Nature Communications |
| 5008 | Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology | Xikun Han (+15) | 2019 | Human Molecular Genetics |
| 8896 | Functional disease architectures reveal unique biological role of transposable elements | Farhad Hormozdiari (+10) | 2019 | Nature Communications |
| 5116 | Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics | Akira Wiberg (+9) | 2019 | Brain |
| 5734 | Sex-specific Mendelian randomization study of genetically predicted insulin and cardiovascular events in the UK Biobank | Jie V. Zhao (+2) | 2019 | Communications Biology |
| 3366 | Extreme inbreeding in a European ancestry sample from the contemporary UK population | Loic Yengo (+2) | 2019 | Nature Communications |
| 8895 | Effect of Systolic Blood Pressure on Left Ventricular Structure and Function | Tom Hendriks (+6) | 2019 | Hypertension |
| 8894 | Inferring whole-genome histories in large population datasets | Jerome Kelleher (+5) | 2019 | Nature Genetics |
| 2709 | Indicators of mental disorders in UK Biobank-A comparison of approaches | Davis KAS et al. | 2019 | Int J Methods Psychiatr Res |
| 3934 | A Prospective Analysis of Genetic Variants Associated with Human Lifespan | Kevin M Wright (+12) | 2019 | G3: Genes, Genomes, Genetics |
| 4137 | Association between exposure to air pollution and hippocampal volume in adults in the UK Biobank | Hedges DW et al. | 2019 | Neurotoxicology |
| 4466 | Changes in Cardiac Morphology and Function in Individuals With Diabetes Mellitus: The UK Biobank Cardiovascular Magnetic Resonance Substudy | Jensen MT et al. | 2019 | Circ Cardiovasc Imaging |
| 4660 | Determinants of impaired lung function and lung cancer prediction among never-smokers in the UK Biobank cohort | Warkentin MT et al. | 2019 | EBioMedicine |
| 4941 | Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration | Wilman HR et al. | 2019 | J Hepatol |
| 5752 | Sleep Duration and Myocardial Infarction | Iyas Daghlas (+6) | 2019 | Journal of the American College of Cardiology |
| 5781 | Structural brain imaging correlates of general intelligence in UK Biobank | S.R. Cox (+4) | 2019 | Intelligence |
| 5952 | Uric acid level, gout and bone mineral density: A Mendelian randomization study | Lee YH et al. | 2019 | Eur J Clin Invest |
| 7291 | The association of grip strength with health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study | Frederick K W Ho (+12) | 2019 | Age and Ageing |
| 5306 | Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior | Andrea Ganna (+20) | 2019 | Science |
| 5456 | Neuroticism as a Predictor of Frailty in Old Age: A Genetically Informative Approach. | Hilda Björk Daníelsdóttir (+8) | 2019 | Psychosomatic Medicine |
| 5040 | Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank | Meng W et al. | 2019 | Commun Biol |
| 8893 | Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank | Weihua Meng (+11) | 2019 | Communications Biology |
| 4512 | Clarin-2 is essential for hearing by maintaining stereocilia integrity and function | Lucy A Dunbar (+31) | 2019 | EMBO Molecular Medicine |
| 5797 | Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants | Chia-Ling Kuo (+4) | 2019 | Aging Cell |
| 2579 | Age at menopause and lung function: a Mendelian randomisation study | Diana A. van der Plaat (+11) | 2019 | European Respiratory Journal |
| 4431 | Case-Only Analysis of Gene-Environment Interactions Using Polygenic Risk Scores | Allison Meisner (+2) | 2019 | American Journal of Epidemiology |
| 5873 | The Longevity-Associated SH2B3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects | Chia-Ling Kuo (+6) | 2019 | The Journals of Gerontology Series A |
| 4149 | Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank | Anwar Mulugeta (+3) | 2019 | Molecular Psychiatry |
| 5857 | The genetic relationship between female reproductive traits and six psychiatric disorders | Guiyan Ni (+5) | 2019 | Scientific Reports |
| 3928 | A polygenic score for body mass index is associated with depressive symptoms via early life stress: Evidence for gene-environment correlation | Reut Avinun (+1) | 2019 | Journal of Psychiatric Research |
| 4620 | Cross-sectional and longitudinal associations between active commuting and patterns of movement behaviour during discretionary time: A compositional data analysis | Louise Foley (+5) | 2019 | PLOS ONE |
| 5942 | Understanding cognitive impairment in mood disorders: mediation analyses in the UK Biobank cohort | Breda Cullen (+5) | 2019 | The British Journal of Psychiatry |
| 3912 | A meta-analysis of genome-wide association studies identifies multiple longevity genes | Deelen J et al. | 2019 | Nat Commun |
| 3391 | GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits | Raha Pazoki (+10) | 2019 | Nature Communications |
| 5009 | Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes | Heming Wang (+44) | 2019 | Nature Communications |
| 5117 | Health effects associated with serum calcium concentrations: evidence from MR-PheWAS analysis in UK Biobank | A. Zhou (+2) | 2019 | Osteoporosis International |
| 2730 | Social engagement after stroke - is it relevant to cognitive function? A cross-sectional analysis of UK Biobank data | Bogna A. Drozdowska (+3) | 2019 | AMRC Open Research |
| 4207 | Association of Lifestyle and Genetic Risk With Incidence of Dementia | Lourida I et al. | 2019 | JAMA |
| 2907 | The Associations of Diuretics and Laxatives Use with Cardiovascular Mortality. An Individual Patient-Data Meta-analysis of Two Large Cohort Studies | Liesa Katharina Hoppe (+4) | 2019 | Cardiovascular Drugs and Therapy |
| 3302 | Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank | Huanwei Wang (+12) | 2019 | Science Advances |
| 2591 | The associations between self-reported depression, self-reported chronic inflammatory conditions and cognitive abilities in UK Biobank | Lyall LM et al. | 2019 | Eur Psychiatry |
| 2644 | GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores | Mullins N et al. | 2019 | Am J Psychiatry |
| 4226 | Association of Rare Copy Number Variants With Risk of Depression | Kendall KM et al. | 2019 | JAMA Psychiatry |
| 4247 | Associations between active travel and diet: cross-sectional evidence on healthy, low-carbon behaviours from UK Biobank | Michaela A Smith (+4) | 2019 | BMJ Open |
| 4780 | Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations | Barfield R et al. | 2019 | Sleep |
| 4930 | Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study | Cerani A et al. | 2019 | BMJ |
| 5648 | Rationale and tutorial for analysing and reporting sex differences in cardiovascular associations | Mark Woodward | 2019 | Heart |
| 5794 | Systolic Blood Pressure and Risk of Valvular Heart Disease: A Mendelian Randomization Study | Nazarzadeh M et al. | 2019 | JAMA Cardiol |
| 12910 | Genome-wide association study of breakfast skipping links clock regulation with food timing | Hassan S Dashti (+26) | 2019 | American Journal of Clinical Nutrition |
| 12911 | Sex differences in the association of risk factors for heart failure incidence and mortality | Anne Sillars (+6) | 2019 | Heart |
| 4067 | Analysis of genetic networks regulating refractive eye development in collaborative cross progenitor strain mice reveals new genes and pathways underlying human myopia | Tatiana V. Tkatchenko (+3) | 2019 | BMC Medical Genomics |
| 5007 | Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema | Åsa Johansson (+3) | 2019 | Human Molecular Genetics |
| 7510 | Stochastic Lanczos estimation of genomic variance components for linear mixed-effects models | Richard Border (+1) | 2019 | BMC Bioinformatics |
| 3974 | Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture | Kangcheng Hou (+7) | 2019 | Nature Genetics |
| 5458 | New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders | Evangelos Evangelou (+97) | 2019 | Nature Human Behaviour |
| 5396 | Methylmercury exposure, genetic variation in metabolic enzymes, and the risk of glioma | Jordan H. Creed (+10) | 2019 | Scientific Reports |
| 5530 | Phenome-wide Burden of Copy-Number Variation in the UK Biobank | Matthew Aguirre (+2) | 2019 | American Journal of Human Genetics |
| 5641 | RaPID: ultra-fast, powerful, and accurate detection of segments identical by descent (IBD) in biobank-scale cohorts | Ardalan Naseri (+4) | 2019 | Genome Biology |
| 5660 | Relationship Between Diet, Tinnitus, and Hearing Difficulties | Piers Dawes (+4) | 2019 | Ear & Hearing |
| 8892 | Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits | Eleonora Porcu (+5) | 2019 | Nature Communications |
| 7511 | Normative brain volumetry derived from different reference populations: impact on single-subject diagnostic assessment in dementia | Elisabeth J. Vinke (+11) | 2019 | Neurobiology of Aging |
| 4071 | Analytical strategies to include the X-chromosome in variance heterogeneity analyses: Evidence for trait-specific polygenic variance structure | Wei Q. Deng (+6) | 2019 | Genetic Epidemiology |
| 3416 | A Powerful Global Test Statistic for Functional Statistical Inference. | Jingwen Zhang (+3) | 2019 | Proceedings of the AAAI Conference on Artificial Intelligence |
| 4134 | Association between coffee consumption and overall risk of being diagnosed with or dying from cancer among >300 000 UK Biobank participants in a large-scale Mendelian randomization study | Jue-Sheng Ong (+7) | 2019 | International Journal of Epidemiology |
| 4808 | Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk | Xiang Shu (+29) | 2019 | International Journal of Cancer |
| 4202 | Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms | Nima C. Emami (+11) | 2019 | Nature Communications |
| 6000 | Weakly supervised classification of aortic valve malformations using unlabeled cardiac MRI sequences | Jason A. Fries (+13) | 2019 | Nature Communications |
| 8891 | Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa | Hunna J. Watson (+209) | 2019 | Nature Genetics |
| 2530 | Air pollution, lung function and COPD: results from the population-based UK Biobank study | Dany Doiron (+6) | 2019 | European Respiratory Journal |
| 3448 | The effect of X-linked dosage compensation on complex trait variation | Julia Sidorenko (+11) | 2019 | Nature Communications |
| 5019 | Genome-wide association study of peripheral artery disease in the Million Veteran Program | Derek Klarin (+35) | 2019 | Nature Medicine |
| 7339 | Reconciling S-LDSC and LDAK functional enrichment estimates | Steven Gazal (+3) | 2019 | Nature Genetics |
| 3054 | The UKB envirome of depression: from interactions to synergistic effects | Gabor Hullam (+6) | 2019 | Scientific Reports |
| 4766 | Efficient haplotype matching between a query and a panel for genealogical search | Ardalan Naseri (+3) | 2019 | Bioinformatics |
| 4035 | Altered Cortical Brain Structure and Increased Risk for Disease Seen Decades After Perinatal Exposure to Maternal Smoking: A Study of 9000 Adults in the UK Biobank | Lauren E Salminen (+14) | 2019 | Cerebral Cortex |
| 2838 | Assessment of Relative Utility of Underlying vs Contributory Causes of Death | Batty GD et al. | 2019 | JAMA Netw Open |
| 4087 | ARMC5 Variants and Risk of Hypertension in Blacks: MH-GRID Study | Mihail Zilbermint (+8) | 2019 | Journal of the American Heart Association |
| 5369 | Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour | Eleanor Sanderson (+3) | 2019 | Nature Communications |
| 3629 | Physical activity and left ventricular trabeculation in the UK Biobank community-based cohort study | Woodbridge SP et al. | 2019 | Heart |
| 4395 | Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk | Dag Alnæs (+29) | 2019 | JAMA Psychiatry |
| 4455 | Causal relationship between years of education and the occurrence of rheumatoid arthritis | Bae SC et al. | 2019 | Postgrad Med J |
| 4985 | Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank | Wang Q et al. | 2019 | EBioMedicine |
| 5620 | PRSice-2: Polygenic Risk Score software for biobank-scale data | Shing Wan Choi (+1) | 2019 | GigaScience |
| 5672 | Reserve and Alzheimer's disease genetic risk: Effects on hospitalization and mortality | Filshtein TJ et al. | 2019 | Alzheimers Dement |
| 5666 | Relevance of physical function in the association of red and processed meat intake with all-cause, cardiovascular, and cancer mortality | Stavroula Argyridou (+4) | 2019 | Nutrition Metabolism and Cardiovascular Diseases |
| 5878 | The occupations at increased risk of COPD: analysis of lifetime job-histories in the population-based UK Biobank Cohort | Sara De Matteis (+7) | 2019 | European Respiratory Journal |
| 5268 | Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study | Richmond RC et al. | 2019 | BMJ |
| 5344 | Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality | Benn M et al. | 2019 | J Am Coll Cardiol |
| 2654 | Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data | Dmitry Shungin (+37) | 2019 | Nature Communications |
| 2856 | Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants | Kenneth Fung (+7) | 2019 | Scientific Reports |
| 12912 | Identification of Novel Causal Blood Biomarkers Linking Metabolically Favorable Adiposity With Type 2 Diabetes Risk | Marie Pigeyre (+7) | 2019 | Diabetes Care |
| 4266 | Associations Between Measures of Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Cohort Study and Mendelian Randomization Analysis Using the UK Biobank | Ruth E. Farmer (+9) | 2019 | Journal of the American Heart Association |
| 4718 | Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury? | Robin B. Brown (+4) | 2019 | Stroke |
| 2846 | Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease: Data from UK Biobank | Claire Welsh (+15) | 2019 | Circulation |
| 5142 | Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank | Lisa Nobis (+6) | 2019 | NeuroImage Clinical |
| 4938 | Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases | Ntalla I et al. | 2019 | J Am Coll Cardiol |
| 2147 | Differential associations of engagement in physical activity and estimated cardiorespiratory fitness with brain volume in middle-aged to older adults | David A. Raichlen (+3) | 2019 | Brain Imaging and Behavior |
| 4846 | Factors associated with potentially serious incidental findings and with serious final diagnoses on multi-modal imaging in the UK Biobank Imaging Study: A prospective cohort study | Lorna M. Gibson (+12) | 2019 | PLOS ONE |
| 7512 | Macrothrombocytopenia associated with a rare GFI1B missense variant confounding the presentation of immune thrombocytopenia | Aaron N. Cheng (+3) | 2019 | Pediatric Blood & Cancer |
| 4921 | Genetic influences on treatment-seeking for common mental health problems in the UK biobank | Christopher Rayner (+10) | 2019 | Behaviour Research and Therapy |
| 5678 | Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans | Kristina M. Garske (+14) | 2019 | Nature Metabolism |
| 7513 | Genome-wide association study of multisite chronic pain in UK Biobank | Keira J. A. Johnston (+8) | 2019 | PLOS Genetics |
| 8890 | Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb | Lars G. Fritsche (+17) | 2019 | PLOS Genetics |
| 3953 | A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids | Todd L. Edwards (+26) | 2019 | Frontiers in Genetics |
| 5549 | Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study | Yogini V. Chudasama (+7) | 2019 | BMC Medicine |
| 7354 | Estimation of brain age delta from brain imaging | Stephen M. Smith (+4) | 2019 | NeuroImage |
| 8889 | Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification | Kristi Läll (+8) | 2019 | BMC Cancer |
| 8888 | Towards an optimised processing pipeline for diffusion magnetic resonance imaging data: Effects of artefact corrections on diffusion metrics and their age associations in UK Biobank | Ivan I. Maximov (+2) | 2019 | Human Brain Mapping |
| 11965 | Genetically modulated educational attainment and coronary disease risk | Lingyao Zeng (+10) | 2019 | European Heart Journal |
| 4720 | Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study | Carlos A. Celis-Morales (+12) | 2019 | International Journal of Obesity |
| 11966 | The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function | Joey Ward (+16) | 2019 | Molecular Psychiatry |
| 2705 | Assessing for interaction between APOE ε4, sex, and lifestyle on cognitive abilities | Lyall DM et al. | 2019 | Neurology |
| 8887 | Statin use and risk of liver cancer: Evidence from two population-based studies | Kim Tu Tran (+7) | 2019 | International Journal of Cancer |
| 8886 | The impact of GDF-15, a biomarker for metformin, on the risk of coronary artery disease, breast and colorectal cancer, and type 2 diabetes and metabolic traits: a Mendelian randomisation study | Shiu Lun Au Yeung (+2) | 2019 | Diabetologia |
| 2845 | Urinary Sodium Excretion, Blood Pressure, and Risk of Future Cardiovascular Disease and Mortality in Subjects Without Prior Cardiovascular Disease | C.E. Welsh (+11) | 2019 | Hypertension |
| 2882 | Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis | Thompson WD et al. | 2019 | PLoS Med |
| 4295 | Associations of genetically determined iron status across the phenome: A mendelian randomization study | Gill D et al. | 2019 | PLoS Med |
| 4415 | Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes: A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank | Hindy G et al. | 2019 | Arthritis Rheumatol |
| 4570 | Comparative Relevance of Physical Fitness and Adiposity on Life Expectancy: A UK Biobank Observational Study | Zaccardi F et al. | 2019 | Mayo Clin Proc |
| 5461 | New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances | Liang-Dar Hwang (+13) | 2019 | American Journal of Clinical Nutrition |
| 11968 | Mendelian Randomization Study for Genetically Predicted Polyunsaturated Fatty Acids Levels on Overall Cancer Risk and Mortality | Upekha E. Liyanage (+5) | 2019 | Cancer Epidemiology Biomarkers & Prevention |
| 3102 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Matthias Wuttke (+326) | 2019 | Nature Genetics |
| 7284 | ukbtools: An R package to manage and query UK Biobank data | Ken B. Hanscombe (+3) | 2019 | PLOS ONE |
| 7283 | Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland | Sini Kerminen (+11) | 2019 | American Journal of Human Genetics |
| 8200 | A comparison of two workflows for regulome and transcriptome-based prioritization of genetic variants associated with myocardial mass | Elisabetta Manduchi (+9) | 2019 | Genetic Epidemiology |
| 3918 | A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity | Sven J. van der Lee (+100) | 2019 | Acta Neuropathologica |
| 3127 | Quantitative CMR population imaging on 20,000 subjects of the UK Biobank imaging study: LV/RV quantification pipeline and its evaluation | Rahman Attar (+15) | 2019 | Medical Image Analysis |
| 4180 | Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank | Lyn D Ferguson (+8) | 2019 | Rheumatology |
| 7282 | Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis | Harry D Green (+12) | 2019 | Journal of Crohn's and Colitis |
| 8885 | The role of neuroticism in self-harm and suicidal ideation: results from two UK population-based cohorts | Jonathan D. Hafferty (+10) | 2019 | Social Psychiatry and Psychiatric Epidemiology |
| 11976 | Germline selection shapes human mitochondrial DNA diversity | Wei Wei (+398) | 2019 | Science |
| 3890 | A genome-wide association study-derived polygenic score for interleukin-1β is associated with hippocampal volume in two samples | Reut Avinun (+4) | 2019 | Human Brain Mapping |
| 5946 | Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study | Carter AR et al. | 2019 | BMJ |
| 2822 | Evidence for Genetic Correlations and Bidirectional, Causal Effects Between Smoking and Sleep Behaviors | Gibson M et al. | 2019 | Nicotine Tob Res |
| 8884 | Genotype-covariate correlation and interaction disentangled by a whole-genome multivariate reaction norm model | Guiyan Ni (+5) | 2019 | Nature Communications |
| 4128 | Association between birth weight and refractive error in adulthood: a Mendelian randomisation study | Denis Plotnikov (+2) | 2019 | British Journal of Ophthalmology |
| 8178 | Sub-phenotyping Metabolic Disorders Using Body Composition: An Individualized, Nonparametric Approach Utilizing Large Data Sets | Jennifer Linge (+3) | 2019 | Obesity |
| 4421 | Cardiovascular disease risk prediction using automated machine learning: A prospective study of 423,604 UK Biobank participants | Ahmed M. Alaa (+4) | 2019 | PLOS ONE |
| 8883 | Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis | John A. Lees (+39) | 2019 | Nature Communications |
| 4200 | Association of habitual glucosamine use with risk of cardiovascular disease: prospective study in UK Biobank | Hao Ma (+7) | 2019 | The BMJ |
| 8881 | Association analyses identify 31 new risk loci for colorectal cancer susceptibility | Philip J. Law (+97) | 2019 | Nature Communications |
| 8882 | Genetic variation in CADM2 as a link between psychological traits and obesity | Julia Morris (+23) | 2019 | Scientific Reports |
| 4380 | Body Fat Distribution and Systolic Blood Pressure in 10,000 Adults with Whole-Body Imaging: UK Biobank and Oxford BioBank | Deborah Malden (+6) | 2019 | Obesity |
| 2620 | Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study | Thomas J Littlejohns (+5) | 2019 | European Urology Focus |
| 2824 | The effect of smoking intensity on all-cause and cause-specific mortality - a Mendelian randomization analysis | Gunnhild Åberge Vie (+8) | 2019 | International Journal of Epidemiology |
| 3861 | A commonly occurring genetic variant within the NPLOC4-TSPAN10-PDE6G gene cluster is associated with the risk of strabismus | Denis Plotnikov (+8) | 2019 | Human Genetics |
| 8880 | Homozygosity for TYK2 P1104A underlies tuberculosis in about 1% of patients in a cohort of European ancestry | Gaspard Kerner (+10) | 2019 | Proceedings of the National Academy of Sciences of the United States of America |
| 7661 | The relationship between sleep duration, cognition and dementia: a Mendelian randomization study | Albert Henry (+7) | 2019 | International Journal of Epidemiology |
| 8879 | Specific physical activities, sedentary behaviours and sleep as long-term predictors of accelerometer-measured physical activity in 91,648 adults: a prospective cohort study | Youngwon Kim (+7) | 2019 | International Journal of Behavioral Nutrition and Physical Activity |
| 8878 | Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development | Alfred Pozarickij (+3) | 2019 | Communications Biology |
| 4191 | Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study | Polimanti R et al. | 2019 | JAMA Netw Open |
| 8835 | GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures | Unnur Styrkarsdottir (+51) | 2019 | Nature Communications |
| 4474 | Characteristics, comorbidities, and correlates of atypical depression: evidence from the UK Biobank Mental Health Survey | Anamaria Brailean (+4) | 2019 | Psychological Medicine |
| 8833 | Genome-wide association study of type 2 diabetes in Africa | Ji Chen (+16) | 2019 | Diabetologia |
| 8834 | Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms | Rebecca S Fine (+4) | 2019 | American Journal of Human Genetics |
| 2568 | Habitual coffee consumption and risk of falls in 2 European cohorts of older adults | Marcos D Machado-Fragua (+5) | 2019 | American Journal of Clinical Nutrition |
| 2660 | Variations in reproductive events across life: a pooled analysis of data from 505 147 women across 10 countries | InterLACE Study Team. | 2019 | Hum Reprod |
| 2904 | Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors | Warrington NM et al. | 2019 | Nat Genet |
| 4072 | Anatomical selectivity in overlap of chronic facial and bodily pain | Gary D. Slade (+9) | 2019 | PAIN Reports |
| 4342 | BGData - A Suite of R Packages for Genomic Analysis with Big Data | Alexander Grueneberg (+1) | 2019 | G3: Genes, Genomes, Genetics |
| 4530 | Coffee consumption by type and risk of digestive cancer: a large prospective cohort study | Kim Tu Tran (+3) | 2019 | British Journal of Cancer |
| 8831 | Genes with High Network Connectivity Are Enriched for Disease Heritability | Samuel S. Kim (+11) | 2019 | American Journal of Human Genetics |
| 8832 | Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse | Mengyao Yu (+17) | 2019 | Circulation Genomic and Precision Medicine |
| 11986 | Imperfect Linkage Disequilibrium Generates Phantom Epistasis (& Perils of Big Data) | Gustavo de los Campos (+2) | 2019 | G3: Genes, Genomes, Genetics |
| 4016 | Age-Related Differences in Brain Morphology and the Modifiers in Middle-Aged and Older Adults | Lu Zhao (+5) | 2019 | Cerebral Cortex |
| 5738 | Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies | Milton Pividori (+4) | 2019 | The Lancet Respiratory Medicine |
| 2770 | Poorer Speech Reception Threshold in Noise Is Associated With Lower Brain Volume in Auditory and Cognitive Processing Regions. | Mary Rudner (+4) | 2019 | Journal of Speech Language and Hearing Research |
| 2853 | Reflection on modern methods: calculating a sample size for a repeatability sub-study to correct for measurement error in a single continuous exposure | Katy E Morgan (+3) | 2019 | International Journal of Epidemiology |
| 3453 | Genome-wide association study of medication-use and associated disease in the UK Biobank | Yeda Wu (+8) | 2019 | Nature Communications |
| 5489 | Obesity, Brain Volume, and White Matter Microstructure at MRI: A Cross-sectional UK Biobank Study | Ilona A Dekkers (+2) | 2019 | Radiology |
| 5977 | Validation of concurrent preimplantation genetic testing for polygenic and monogenic disorders, structural rearrangements, and whole and segmental chromosome aneuploidy with a single universal platform | Nathan R Treff (+16) | 2019 | European Journal of Medical Genetics |
| 8829 | Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis | Sarah E. Graham (+20) | 2019 | Nature Communications |
| 8830 | Genome sequencing for rightward hemispheric language dominance | Amaia Carrion-Castillo (+10) | 2019 | Genes Brain & Behavior |
| 4335 | Automatic CNN-based detection of cardiac MR motion artefacts using k-space data augmentation and curriculum learning | Ilkay Oksuz (+10) | 2019 | Medical Image Analysis |
| 2830 | Body composition and atrial fibrillation: a Mendelian randomization study | Tikkanen E et al. | 2019 | Eur Heart J |
| 2946 | Driving status, travel modes and accelerometer-assessed physical activity in younger, middle-aged and older adults: a prospective study of 90 810 UK Biobank participants | Samantha Hajna (+8) | 2019 | International Journal of Epidemiology |
| 7332 | Polygenic prediction via Bayesian regression and continuous shrinkage priors | Tian Ge (+4) | 2019 | Nature Communications |
| 5895 | The spatial correspondence and genetic influence of interhemispheric connectivity with white matter microstructure | Jeroen Mollink (+9) | 2019 | Nature Neuroscience |
| 7328 | Predictive Big Data Analytics using the UK Biobank Data | Yiwang Zhou (+8) | 2019 | Scientific Reports |
| 7662 | The molecular genetics of hand preference revisited | Carolien G. F. de Kovel (+1) | 2019 | Scientific Reports |
| 8828 | Genetic Association of Finger Photoplethysmography-Derived Arterial Stiffness Index With Blood Pressure and Coronary Artery Disease | Seyedeh M Zekavat (+6) | 2019 | Arteriosclerosis Thrombosis and Vascular Biology |
| 2836 | Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort | Bhautesh Dinesh Jani (+6) | 2019 | BMC Medicine |
| 7327 | Selection Bias When Estimating Average Treatment Effects Using One-sample Instrumental Variable Analysis | Rachael A. Hughes (+3) | 2019 | Epidemiology |
| 8827 | Insulin resistance: Genetic associations with depression and cognition in population based cohorts | Sophia Frangou (+13) | 2019 | Experimental Neurology |
| 8826 | Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour | Samuel E. Jones (+31) | 2019 | Nature Communications |
| 2145 | Polygenic Risk Score Is Associated With Intraocular Pressure and Improves Glaucoma Prediction in the UK Biobank Cohort | X. Raymond Gao (+2) | 2019 | Translational Vision Science & Technology |
| 7663 | Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis | Zhaozhong Zhu (+12) | 2019 | Respiratory Research |
| 3183 | Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity | Luca A. Lotta (+18) | 2019 | Cell |
| 4111 | Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study | Choi KW et al. | 2019 | JAMA Psychiatry |
| 4170 | Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents: A Voxelwise and Genome-Wide Association Study | Luo Q et al. | 2019 | JAMA Psychiatry |
| 4580 | Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals: a systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies | Smith T et al. | 2019 | Gut |
| 4889 | Genetic and observational evidence supports a causal role of sex hormones on the development of asthma | Ryan Arathimos (+6) | 2019 | Thorax |
| 5237 | Inferring Multidimensional Rates of Aging from Cross-Sectional Data. | Emma Pierson (+6) | 2019 | Proceedings of machine learning research |
| 8825 | Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood | Amit V. Khera (+18) | 2019 | Cell |
| 11987 | Effect of glutamate and aspartate on ischemic heart disease, blood pressure, and diabetes: a Mendelian randomization study | Jie V Zhao (+2) | 2019 | American Journal of Clinical Nutrition |
| 8824 | Chronotype Genetic Variant in PER2 is Associated with Intrinsic Circadian Period in Humans | Anne-Marie Chang (+24) | 2019 | Scientific Reports |
| 8823 | Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct | Manuel A.R. Ferreira (+18) | 2019 | American Journal of Human Genetics |
| 5367 | Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease | Eirini Marouli (+16) | 2019 | Communications Biology |
| 5512 | Parent of origin genetic effects on methylation in humans are common and influence complex trait variation | Yanni Zeng (+22) | 2019 | Nature Communications |
| 7514 | Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches | Stephen F. Weng (+3) | 2019 | PLOS ONE |
| 4381 | Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses | Yi-Qian Sun (+15) | 2019 | The BMJ |
| 7515 | Mood Instability and Trait Anxiety as Distinct Components of Eysenckian Neuroticism With Differential Relations to Impulsivity and Risk Taking | Evyn M. Peters (+2) | 2019 | Journal of Personality Assessment |
| 2729 | Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity | Donald M. Lyall (+13) | 2019 | Brain Imaging and Behavior |
| 5653 | Reduced signal for polygenic adaptation of height in UK Biobank | Jeremy J Berg (+10) | 2019 | eLife |
| 11989 | The Combination of Physical Activity and Sedentary Behaviors Modifies the Genetic Predisposition to Obesity | Carlos A. Celis-Morales (+11) | 2019 | Obesity |
| 5994 | Vitamin D levels and risk of delirium: A mendelian randomization study in the UK Biobank | Bowman K et al. | 2019 | Neurology |
| 8822 | Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort | Golam M. Khandaker (+8) | 2019 | Molecular Psychiatry |
| 4000 | Age and cognitive decline in the UK Biobank | Marilyn C. Cornelis (+5) | 2019 | PLOS ONE |
| 5930 | Type 2 Diabetes and Hypertension | Sun D et al. | 2019 | Circ Res |
| 7323 | Potential influence of socioeconomic status on genetic correlations between alcohol consumption measures and mental health | Andries T. Marees (+8) | 2019 | Psychological Medicine |
| 2742 | A Frailty Index for UK Biobank Participants | Williams DM et al. | 2019 | J Gerontol A Biol Sci Med Sci |
| 4903 | Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life | W. David Hill (+8) | 2019 | Molecular Psychiatry |
| 2832 | Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion | Daniela Zanetti (+5) | 2019 | Kidney International |
| 4276 | Associations between vascular risk factors and brain MRI indices in UK Biobank | Simon R Cox (+23) | 2019 | European Heart Journal |
| 8821 | Interrogation of human hematopoiesis at single-cell and single-variant resolution | Jacob C. Ulirsch (+13) | 2019 | Nature Genetics |
| 7516 | No Support for Historical Candidate Gene or Candidate Gene-by-Interaction Hypotheses for Major Depression Across Multiple Large Samples | Richard Border (+6) | 2019 | American Journal of Psychiatry |
| 8820 | Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates | Hassan S. Dashti (+31) | 2019 | Nature Communications |
| 2152 | Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank | Luo S et al. | 2019 | BMJ |
| 3185 | The influence of X chromosome variants on trait neuroticism | Michelle Luciano (+9) | 2019 | Molecular Psychiatry |
| 8819 | Schizophrenia risk and reproductive success: a Mendelian randomization study | Rebecca B. Lawn (+9) | 2019 | Royal Society Open Science |
| 4044 | An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome | Tom G Richardson (+3) | 2019 | eLife |
| 7517 | Assessing the causal association of glycine with risk of cardio-metabolic diseases | Laura B. L. Wittemans (+22) | 2019 | Nature Communications |
| 8818 | Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci | Tom Dudding (+14) | 2019 | Nature Communications |
| 3881 | A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome | Akira Wiberg (+9) | 2019 | Nature Communications |
| 1702 | Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank | Crawford K et al. | 2019 | J Med Genet |
| 2525 | Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide | Strawbridge RJ et al. | 2019 | EBioMedicine |
| 2714 | Low neuroticism and cognitive performance are differently associated to overweight and obesity: A cross-sectional and longitudinal UK Biobank study | Olivo G et al. | 2019 | Psychoneuroendocrinology |
| 2758 | Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases | Ang Zhou (+1) | 2019 | American Journal of Clinical Nutrition |
| 4517 | Clinical Utility and Practical Considerations of a Coronary Artery Disease Genetic Risk Score | Liu R et al. | 2019 | CJC Open |
| 7345 | Walking Pace Is Associated with Lower Risk of All-Cause and Cause-Specific Mortality | Carlos A Celis-Morales (+11) | 2019 | Medicine & Science in Sports & Exercise |
| 4011 | Age-dependent co-dependency structure of biomarkers in the general population of the United States | Alan Le Goallec (+1) | 2019 | Aging |
| 8698 | Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer | Stephanie A. Bien (+77) | 2019 | Human Genetics |
| 7348 | Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization | David M Evans (+4) | 2019 | International Journal of Epidemiology |
| 8697 | Investigating causality in the association between vitamin D status and self-reported tiredness | Alexandra Havdahl (+3) | 2019 | Scientific Reports |
| 3207 | Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes | Maxim Freidin (+8) | 2019 | Journal of Medical Genetics |
| 8696 | Identifying dementia outcomes in UK Biobank: a validation study of primary care, hospital admissions and mortality data | Tim Wilkinson (+12) | 2019 | European Journal of Epidemiology |
| 11990 | Efficient Implementation of Penalized Regression for Genetic Risk Prediction | Florian Privé (+2) | 2019 | Genetics |
| 1944 | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries | Nick Shrine (+108) | 2019 | Nature Genetics |
| 2748 | Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations | Phuwanat Sakornsakolpat (+53) | 2019 | Nature Genetics |
| 4999 | Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways | Philip R. Jansen (+23) | 2019 | Nature Genetics |
| 4488 | Chronotype, depression and hippocampal volume: cross-sectional associations from the UK Biobank | Ray Norbury | 2019 | Chronobiology International |
| 4735 | Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study | Lewis Steell (+14) | 2019 | British Journal of Sports Medicine |
| 8695 | Robust meta-analysis of biobank-based genome-wide association studies with unbalanced binary phenotypes | Rounak Dey (+6) | 2019 | Genetic Epidemiology |
| 4543 | Cohort profile: design and methods in the eye and vision consortium of UK Biobank | Chua SYL et al. | 2019 | BMJ Open |
| 12000 | Social engagement after stroke - is it relevant to cognitive function? A cross-sectional analysis of UK Biobank data | Bogna A. Drozdowska (+3) | 2019 | AMRC Open Research |
| 8693 | Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases | Serena Sanna (+16) | 2019 | Nature Genetics |
| 8694 | Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution | Anne E. Justice (+278) | 2019 | Nature Genetics |
| 12003 | Sarcopenia and Variation in the Human Leukocyte Antigen Complex | Garan Jones (+5) | 2019 | The Journals of Gerontology Series A |
| 1624 | Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts | Atkins JL et al. | 2019 | J Gerontol A Biol Sci Med Sci |
| 4540 | Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank | Kimberley M. Kendall (+9) | 2019 | The British Journal of Psychiatry |
| 8692 | Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection | Armin P. Schoech (+9) | 2019 | Nature Communications |
| 1972 | Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data | Biasiolli L et al. | 2019 | PLoS One |
| 4354 | Biological insights into multiple birth: genetic findings from UK Biobank | Hamdi Mbarek (+12) | 2019 | European Journal of Human Genetics |
| 3923 | A phenome-wide association study to discover pleiotropic effects of PCSK9, APOB, and LDLR | Safarova MS et al. | 2019 | NPJ Genom Med |
| 8691 | Effect of increased body mass index on risk of diagnosis or death from cancer | Puya Gharahkhani (+6) | 2019 | British Journal of Cancer |
| 3210 | Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals | Maxim B Freidin (+6) | 2019 | Pain |
| 2155 | Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals | Richard Border (+15) | 2019 | European Journal of Human Genetics |
| 2661 | Premenopausal cardiovascular disease and age at natural menopause: a pooled analysis of over 170,000 women | Dongshan Zhu (+15) | 2019 | European Journal of Epidemiology |
| 3077 | Physical activity of UK adults with chronic disease: cross-sectional analysis of accelerometer-measured physical activity in 96 706 UK Biobank participants | Joseph Barker (+7) | 2019 | International Journal of Epidemiology |
| 3885 | A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia | Yu Huang (+6) | 2019 | Investigative Ophthalmology & Visual Science |
| 4176 | Association of body mass index and waist-to-hip ratio with brain structure: UK Biobank study | Hamer M et al. | 2019 | Neurology |
| 8690 | Indirect assortative mating for human disease and longevity | Konrad Rawlik (+2) | 2019 | Heredity |
| 2837 | Cognitive ability and risk of death from lower respiratory tract infection: findings from UK Biobank | Catharine R. Gale (+2) | 2019 | Scientific Reports |
| 3050 | Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions | David M. Howard (+37) | 2019 | Nature Neuroscience |
| 3562 | Independent Left Ventricular Morphometric Atlases Show Consistent Relationships with Cardiovascular Risk Factors: A UK Biobank Study | Kathleen Gilbert (+12) | 2019 | Scientific Reports |
| 5055 | Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland | Aleix Arnau-Soler (+9) | 2019 | Translational Psychiatry |
| 7664 | Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes | Wonil Chung (+7) | 2019 | Nature Communications |
| 2706 | Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis | Skaaby T et al. | 2019 | Addiction |
| 2807 | Muscle mass measures and incident osteoporosis in a large cohort of postmenopausal women | Papageorgiou M et al. | 2019 | J Cachexia Sarcopenia Muscle |
| 3051 | Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts | Sanchez-Roige S et al. | 2019 | Am J Psychiatry |
| 4426 | Cardiovascular Risk Factors Associated With Venous Thromboembolism | John Gregson (+73) | 2019 | JAMA Cardiology |
| 7340 | Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization | Louise A. C. Millard (+4) | 2019 | PLOS Genetics |
| 12005 | Mosaic Y loss is moderately associated with solid tumor risk | Erikka Loftfield (+5) | 2019 | Cancer Research |
| 1828 | Identification of 12 genetic loci associated with human healthspan | Aleksandr Zenin (+6) | 2019 | Communications Biology |
| 1863 | Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms | Samuel E. Jones (+31) | 2019 | Nature Communications |
| 3964 | Accelerometer compared with questionnaire measures of physical activity in relation to body size and composition: a large cross-sectional analysis of UK Biobank | Guo W et al. | 2019 | BMJ Open |
| 3652 | A large-scale population study of early life factors influencing left-handedness | Carolien G. F. de Kovel (+2) | 2019 | Scientific Reports |
| 7518 | Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank | Anthony Warland (+4) | 2019 | Molecular Psychiatry |
| 8689 | Genetic architecture of human thinness compared to severe obesity | Fernando Riveros-McKay (+12) | 2019 | PLOS Genetics |
| 8193 | ADRB2 p.Thr164Ile association with hospitalization depends upon asthma severity | Lynn D Condreay (+10) | 2019 | Journal of Allergy and Clinical Immunology |
| 8688 | Sex-specific moderation by lifestyle and psychosocial factors on the genetic contributions to adiposity in 112,151 individuals from UK Biobank | Catherine M. Calvin (+7) | 2019 | Scientific Reports |
| 5252 | Integrating predicted transcriptome from multiple tissues improves association detection | Alvaro N. Barbeira (+5) | 2019 | PLOS Genetics |
| 8686 | Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data | Ioanna Tachmazidou (+20) | 2019 | Nature Genetics |
| 8687 | Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects | Mathias Rask-Andersen (+3) | 2019 | Nature Communications |
| 2815 | Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease | Aaron Leong (+11) | 2019 | Diabetes Care |
| 4082 | Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis | Simon Haworth (+12) | 2019 | Nature Communications |
| 4104 | Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting | Caroline F. Wright (+11) | 2019 | American Journal of Human Genetics |
| 4609 | Correlates of Hearing Aid Use in UK Adults | Chelsea S. Sawyer (+4) | 2019 | Ear & Hearing |
| 7443 | A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect | Katerina Zorina-Lichtenwalter (+6) | 2019 | Human Molecular Genetics |
| 2895 | Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances | Timmers PR et al. | 2019 | Elife |
| 5034 | Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection | Takeuchi F et al. | 2019 | Hum Mol Genet |
| 2160 | Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences | Richard Karlsson Linnér (+91) | 2019 | Nature Genetics |
| 2693 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Mengzhen Liu (+122) | 2019 | Nature Genetics |
| 3908 | A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis | Ragnar P. Kristjansson (+39) | 2019 | Nature Genetics |
| 12014 | Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan | Katherine S Ruth (+14) | 2019 | Human Molecular Genetics |
| 4663 | Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis | Seth A. Sharp (+11) | 2019 | Diabetes Care |
| 8685 | Interactions between serum urate-associated genetic variants and sex on gout risk: analysis of the UK Biobank | Ravi K. Narang (+6) | 2019 | Arthritis Research & Therapy |
| 2711 | Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk | Iris E. Jansen (+52) | 2019 | Nature Genetics |
| 5387 | Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci | A. Mesut Erzurumluoglu (+175) | 2019 | Molecular Psychiatry |
| 8194 | Genetic liability to schizophrenia is negatively associated with educational attainment in UK Biobank | Valentina Escott-Price (+6) | 2019 | Molecular Psychiatry |
| 8684 | Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide | Douglas M. Ruderfer (+6) | 2019 | Molecular Psychiatry |
| 2843 | Right ventricular shape and function: cardiovascular magnetic resonance reference morphology and biventricular risk factor morphometrics in UK Biobank | Charlène Mauger (+11) | 2019 | Journal of Cardiovascular Magnetic Resonance |
| 3141 | Discovery of common and rare genetic risk variants for colorectal cancer | Huyghe JR et al. | 2019 | Nat Genet |
| 4244 | Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank | Barbu MC et al. | 2019 | Biol Psychiatry Cogn Neurosci Neuroimaging |
| 4330 | Automated quality control in image segmentation: application to the UK Biobank cardiovascular magnetic resonance imaging study | Robert Robinson (+21) | 2019 | Journal of Cardiovascular Magnetic Resonance |
| 4815 | Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study | Budu-Aggrey A et al. | 2019 | PLoS Med |
| 5001 | Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension | Ji Y et al. | 2019 | Diabetes |
| 5122 | Hearing Difficulties and Tinnitus in Construction, Agricultural, Music, and Finance Industries: Contributions of Demographic, Health, and Lifestyle Factors | Samuel Couth (+4) | 2019 | Trends in Hearing |
| 5918 | Trans-ethnic association study of blood pressure determinants in over 750,000 individuals | Giri A et al. | 2019 | Nat Genet |
| 8195 | M91 POLYGENIC RISK FOR SCHIZOPHRENIA AND SEASON OF BIRTH WITHIN THE UK BIOBANK COHORT | Valentina Escott-Price (+7) | 2019 | European Neuropsychopharmacology |
| 8683 | OCMA: Fast, Memory-Efficient Factorization of Prohibitively Large Relationship Matrices | Zhi Xiong (+6) | 2019 | G3: Genes, Genomes, Genetics |
