| Title: | Assessing Optimal Treatment Protocols for Pelvic Fractures in Motor Vehicle Accident Patients |
| Lead Institution: | Chinese PLA General Hospital |
| Principal investigator: |
Application 716731
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Research Questions: Does early internal fixation improve survival rates within the first 30 days post-injury in patients with motor vehicaccident(MVA)-induced pelvic fractures? How do early internal fixation, delayed fixation, and non-surgical treatments compare in terms of complication raes, pain management, functional recovery, and length of hospital stay? What factors (e.g. fracture type, patient demographics, coexisting injuries) influence the selection and efficacy otreatment modalities for MVA-related pelvic fractures? Objectives: To evaluate the impact of early internal fixation on survival rates in patients with VA-induced pelvic fractures. To compare the efficacy of early internal fixation, delayed fixation, and non-surgical treatments in terms of clinicaoutcomes. To identify factors that influence treatment selection and patient outcomes. To establish evidence-based guidelines for the management of MVA-related pelvic fractures. Scientific Rationale! Pelvic fractures resulting from MVAs are associated with high morbidity and mortality due to severe structural and vascular damage. The lack of standardized treatment protocols leads to variability in management and patient outcomes. Early internal fixation may stabilize fractures, prevent life-threatening complications (e.g., hemorrhage, shock), and improve survival rates. However, evidence comparing early fixation with delayed or non-surgical approaches is limited. This study aims to fill this gap by evaluating the efficacy of different treatment protocols,focusing on survival, complications, pain management, and functional recovery. The findings will provide evidence-based insights to optimize treatment strategies, reduce recovery time, and enhance patient outcomes, ultimatelv advancing trauma care and patient-centered recovery.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 17988 | Plasma proteins mediate the protective association between physical activity and osteoporosis risk: A prospective study in the UK biobank | Binbin Liu (+10) | 2026 | Archives of Gerontology and Geriatrics |
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