About
Common diseases including severe or acute diseases, chronic diseases, and cancers, which remain high all over the world, increase the family economic burden, consume public medical resources excessively and cause life quality decreasing. This project mainly focuses on some diseases with increasing significance for the public, including cardiovascular diseases, dementia, breast cancer and lung cancer etc. Risk factor detection research can still be urgent and significant for public health. Due to limitations of some real-world data, some factors were not collected and considered at the same time.
It is important to detect potential risk factors and causal associations prospectively based on this large-scale dataset and provide necessary preventive evidence. This project aims to involve all the necessary subjects from UK Biobank to conduct relative analysis. The effects of sole or combined factors like demographic variables, personal behaviors, medical records, diet models, social test results, metabolic biomarkers, and genetic indications will be considered at the same time. During the detection progress, some important bias-adjustment methods and prediction models will be applied, including parametric and non-parametric regression models.
Since the variable spectrum can be very broad, all the cohort data will be used. The project duration is 3 years. This project is expected to provide more convincing evidence for the underlying mechanism investigation, diagnosis, prevention, and treatment of common diseases. This may help the society to identify some high-risk groups who are more vulnerable to some diseases or some unhealthy conditions. In a world, it is expected to be beneficial to public health care, and decrease the morbidity and mortality of common diseases.
20 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|
| 18053 | Accelerometer-derived 'weekend warrior' physical activity pattern and sleep | Xin Guo (+4) | 2026 | BMC Public Health |
| 12046 | Association between Abortion and All-Cause and Cause-Specific Premature Mortality: A Prospective Cohort Study from the UK Biobank | Shaohua Yin (+6) | 2024 | Health Data Science |
| 15492 | Association between an energy-adjusted inflammatory diet index and gastroesophageal reflux disease: a retrospective cohort study | Yinghong Zhai (+7) | 2025 | European Journal of Nutrition |
| 17807 | Association between energy-adjusted dietary inflammatory index and increased risk of all-cause Crohn's disease: a prospective cohort study | Na Zhao (+7) | 2026 | Frontiers in Public Health |
| 18933 | Association between sepsis and all-cause and cause-specific premature mortality: a prospective cohort study | Wenhui Kang (+8) | 2025 | Frontiers in Public Health |
| 15585 | Association between the inflammatory potential of diet and chronic renal failure: A cohort study of 163 433 UK Biobank participants | Yinghong Zhai (+6) | 2025 | Nutrition |
| 19986 | Association of biological age acceleration with cardiovascular disease and premature mortality: a population-based prospective cohort study | Yingying Yang (+6) | 2026 | Frontiers in Public Health |
| 15545 | Association of birthweight with all-cause and cause-specific premature mortality in the UK: A prospective cohort study | Shaohua Yin (+5) | 2025 | Annals of Epidemiology |
| 18063 | Association of physical activity volume with the risks of nervous system diseases: a retrospective cohort study | Mingming Ye (+4) | 2026 | Frontiers in Neurology |
| 15932 | Association of spontaneous abortion and lifestyle with diabetes mellitus in women: a cross-sectional study in UK Biobank | Sanwei Liu (+5) | 2025 | BMC Pregnancy and Childbirth |
| 14207 | Associations between an energy-adjusted inflammatory diet index and incident depression: a cohort study. | Yinghong Zhai (+8) | 2024 | British Journal Of Nutrition |
| 18092 | Associations between the C-reactive protein-triglyceride glucose index and the incidence and progression trajectory of cardiometabolic multimorbidity: a multi-state model study | Lei Yuan (+8) | 2026 | Cardiovascular Diabetology |
| 8858 | Atrial fibrillation increases the risk of all-cause dementia, Alzheimer's disease, and vascular dementia: A cohort study of 373, 415 participants in the UK Biobank | Yinghong Zhai (+9) | 2024 | Journal of Affective Disorders |
| 19504 | Body roundness index, depression, and the mediating role of lifestyle: Insights from the UK biobank cohort | Yinghong Zhai (+5) | 2025 | Journal of Affective Disorders |
| 18832 | Combined impact of multiple healthy lifestyles on digestive diseases: a large population-based prospective cohort study | Lei Yuan (+12) | 2025 | BMC Medicine |
| 19375 | Decoding sexually dimorphic proteomic landscapes in the context of aging and mortality | Zhihao Jin (+9) | 2025 | Communications Medicine |
| 20180 | Light Exposure, Physical Activity, and Sleep Duration: Evidence of Nonlinear Associations and Interactive Effects in a Large UK Biobank Cohort | Yanfei Zhang (+3) | 2026 | Research Quarterly for Exercise and Sport |
| 18209 | Nonalcoholic fatty liver disease is not associated with the elevated risk of atrial fibrillation: Evidence from the UK biobank cohort study. | Yinghong Zhai (+6) | 2026 | Kardiologia Polska |
| 15784 | Plasma proteomic profiling reveals Parkinson's disease-associated proteins: A UK Biobank study | Xuehao Jiao (+8) | 2025 | Parkinsonism & Related Disorders |
| 16326 | Stillbirth increase long-term health risks of diabetes, CVD, CVD mortality, and all-cause mortality | Yi Shen (+11) | 2025 | BMC Women's Health |
