| Title: | Multi-omics Study of Non-communicable Disease and Their Interaction with Environmental Factors |
| Lead Institution: | Soochow University |
| Principal investigator: |
Application 91185
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About
Noncommunicable diseases are the result of a combination of genetic, physiological, environmental, and behavioral factors, but their etiology remains limited. In the next three years, we will interrogate genomics data, metabolomics data, and environmental factors to better illustrate the molecular mechanism underlying these noncommunicable diseases. Findings from our study could help identify individuals at high risk for active monitoring and intervention. In addition, our findings could provide epidemiological evidence for the novel drug targets of noncommunicable diseases.3 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 11827 | Associations of computer gaming with incident dementia, cognitive functions, and brain structure: a prospective cohort study and Mendelian randomization analysis | Yiming Jia (+17) | 2024 | Alzheimer's Research & Therapy |
| 12074 | Physical Activity, Sleep, and Risk of Late-Onset Severe Mental Illness: A Prospective Cohort Study From UK Biobank | Xiaowei Zheng (+10) | 2024 | Schizophrenia Bulletin |
| 12798 | The association of early life factors with depression and anxiety in adults aged 40-69 years: a population-based cohort study | Ruirui Wang (+8) | 2024 | Translational Psychiatry |
Enabling scientific discoveries that improve human health