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About
Exercise regularly can provide substantial health benefits. However, the optimal time of day to engage in exercise is unknown. This study is aimed to investigate whether the timing of exercise will influence cardiovascular health. The rationale of this study is the emerging evidence regarding the circadian rhythm of human biology. The 2017 Nobel Prize was awarded to 3 scientists for their discoveries of molecular mechanisms controlling the circadian rhythm. Our cardiovascular system responds differently to exercise when performed at different times of the day. Nevertheless, whether those differences are associated with long-term health outcomes remains unclear. With an estimated one-year duration, this study is expected to provide valuable information regarding the timing of exercise and cardiovascular health. The findings are expected to contribute to the worldwide public health initiatives of reducing the burden of cardiovascular disease.