| Title: | Interaction effect of physical activity and environmental factors on health outcomes in general populations |
| Lead Institution: | Central South University |
| Principal investigator: | Professor Xinyin Wu |
Application 64555
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About
It is well established that physical activity is a protective factor for health. For example, evidence has demonstrated that physical activity significantly reduces mortality in terms of all-cause mortality and cause-specific mortality. Nonetheless,) environmental factors (e.g. temperature, UV exposure, Ambient particulate matter, and noise) have shown health effects as well. For instance, air pollution is recognized as the global largest single environmental risk factor for various diseases and mortality. Air pollution caused around 4.2 million death globally each year. It is of significant public health interest to investigate the joint effect on health outcomes between the health benefits of physical activity and the harmful effects of risk environmental factors like air pollution during physical activity. Some evidence dementated that the benefits of physical activity were demolished after acute exposure to temporal high-level air pollution. However, evidence on the interaction between long-term exposure to harmful environmental factors and physical activity to health outcomes is scarce. This study aims to investigate the interactive effect of physical activity and environmental factors, including temperature, UV exposure, Ambient particulate matter, and noise on health outcomes (measured with all-cause mortality, cause-specific mortality, respiratory diseases, cardiovascular diseases, carcinoma, neurodegenerative diseases, and geriatric syndrome, etc.). This study is expected to last for 36 months. Results from this study will provide additional evidence on whether the benefits of physical activity will be affected by environmental factors, develop recommendations for performing physical activity under an optimal environment to maximize its health benefits. Therefore, evidence from this study will have great public health implications for the general population.2 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 8706 | Association of healthy lifestyle behaviours with incident irritable bowel syndrome: a large population-based prospective cohort study | Fai Fai Ho (+11) | 2024 | Gut |
| 7999 | Lifestyle trajectories and ischaemic heart diseases: a prospective cohort study in UK Biobank. | Yinyan Gao (+8) | 2023 | European Journal of Preventive Cardiology |
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