: Application

Application 60009

Title:	Factors Associated with Healthy Ageing
Lead Institution:	Shenzhen Eye Hospital
Principal investigator:	Dr Fu-Rong Li

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About

Aging is associated with a variety of diseases, we aim to identify risk factors for aging-associated diseases (cardiovascular disease, diabetes, cancer, kidney disease, cognitive impairment, etc.) and premature death. Findings from this project will have broad public health implications. First, it will increase our understanding of the aetiology of aging-related health problems and to provide insights into biological mechanisms underlying healthy aging. Second, we will identify modifiable risk factors and that are linked to aging related diseases and therefore help develop interventions to promote healthy ageing. Third, we will also identify genetic factors that are involved in the aging related diseases, and as a result, to guide precision medicine in clinical practice.

14 Publications

Pub ID	Title	Author(s)	Year	Journal
12269	Association of Lifestyle With Incidence of Heart Failure According to Metabolic and Genetic Risk Status: A Population-Based Prospective Study	Zhengbao Zhu (+16)	2022	Circulation Heart Failure
9759	Inflammatory Bowel Disease and Risk of Global Cardiovascular Diseases and Type 2 Diabetes	Zhengbao Zhu (+14)	2023	Inflammatory Bowel Diseases
10581	Influence of hypertension duration and blood pressure levels on cardiovascular disease and all-cause mortality: A large prospective cohort study	Yan Zheng (+4)	2022	Frontiers in Cardiovascular Medicine
7806	Lipoprotein(a), family history of cardiovascular disease, and incidence of heart failure	Hai-Peng Wang (+6)	2023	Journal of Lipid Research
12236	Long-term exposure to air pollution and incident non-alcoholic fatty liver disease and cirrhosis: A cohort study	Fu-Rong Li (+9)	2022	Liver International
7367	Microvascular Burden and Incident Heart Failure Among Middle-Aged and Older Adults With Type 1 or Type 2 Diabetes.	Fu-Rong Li (+5)	2022	Diabetes Care
8646	Microvascular Disease, Cardiovascular Health, and Risk of Coronary Heart Disease in Type 2 Diabetes: A UK Biobank Study	Guo-Chong Chen (+7)	2024	The Journal of Clinical Endocrinology & Metabolism
10142	Microvascular burden and long-term risk of stroke and dementia in type 2 diabetes mellitus	Yu-Jie Liu (+12)	2024	Journal of Affective Disorders
10073	Microvascular disease, modifiable risk factor profiles and incident arrhythmias in type 2 diabetes	Guo-Chong Chen (+7)	2024	Heart
13113	Non-Linear Association of Dietary Polyamines with the Risk of Incident Dementia: Results from Population-Based Cohort of the UK Biobank	Mingxia Qian (+7)	2024	Nutrients
8736	Physical activity and sleep pattern in relation to incident Parkinson's disease: a cohort study	Li-Hua Chen (+12)	2024	International Journal of Behavioral Nutrition and Physical Activity
10885	Relationship Between Fish Oil Use and Incidence of Primary Liver Cancer: Findings From a Population-Based Prospective Cohort Study	Wei Jiang (+4)	2021	Frontiers in Nutrition
7685	Shift work and risk of incident gastroesophageal reflux disease: the association and mediation	Qian Li (+10)	2023	Frontiers in Public Health
8069	The Association Between Exposure to Air Pollution and Dementia Incidence: The Modifying Effect of Smoking	Guo-Chong Chen (+4)	2022	The Journals of Gerontology Series A

Enabling scientific discoveries that improve human health