| Title: | Mortality prediction based on routine blood indexes and biochemical parameters |
| Lead Institution: | Fudan University |
| Principal investigator: | Dr Zhenqiu Liu |
Application 58484
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About
Aims we aim to evaluate the performance of these indices, such as white cell count , in the prediction of mortality and to construct a predicting model based on the large cohort study. The background and scientific rationale of the proposed research project in general. Adequate identification and risk stratification of individuals with deduced life expectancy is an important public health priority and a central issue in clinical decision making. Routine blood test and biochemical examination are commonly used to measure human health status in clinical practice. Previous studies have reported that these biochemical parameters were associated with mortality among the general population. However, the association patterns were diverse across these analytes and their predictive abilities on mortality have rarely been investigated based on a large sample size. Project duration Jan 1st, 2020 to Dec 31th, 2020. Public health impact Our study is informative to identify individuals at high risk of premature death. Our results are of importance for management of high risk population and arrangement of limited medical resources.3 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 7455 | Genetic predisposition, lifestyle risk, and obesity associate with the progression of nonalcoholic fatty liver disease | Zhenqiu Liu (+6) | 2021 | Digestive and Liver Disease |
| 10242 | Investigating the Association Between Seven Sleep Traits and Nonalcoholic Fatty Liver Disease: Observational and Mendelian Randomization Study | Hong Fan (+11) | 2022 | Frontiers in Genetics |
| 8001 | Investigating the Effect of Metabolic Phenotypes on Health Events in Alcoholic and Nonalcoholic Fatty Liver Disease | Hong Fan (+6) | 2023 | Journal of Clinical and Translational Hepatology |
Enabling scientific discoveries that improve human health