| Title: | Analysis of the incidence rate, risk factors, related surgical strategies, postoperative complications and prognosis of urogenital system diseases |
| Lead Institution: | Xiangya Hospital of Central South University |
| Principal investigator: |
Application 529233
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About
This research project aims to investigate the incidence rate, risk factors, surgical strategies, postoperative complications and prognosis of some urogenital system diseases.By analyzing the data from the UK Biobank (a large biomedical database), we hope to reveal the impact of urogenital system diseases on public health. A variety of genitourinary disorders are common in clinical practice, but there are no standardized criteria for their clinical diagnosis, classification and treatment, and there are inconsistencies in the relevant content of different textbooks or guidelines. In order to solve these problems, we will use the data from UKB to analyze some urinary system diseases (including benign prostatic hyperplasia, urinary calculi, urethral stricture, urinary incontinence, neurogenic bladder, ketamine-related cystitis and radiation cystitis, etc.), male and female reproductive system diseases (including genital malformations of both sexes, male infertility and female infertility, etc.), female pelvic organ prolapse-related diseases, surgical strategies (such as for patients with refractory OAB, whether to choose botulinum toxin injection, sacral nerve modulation or tibial nerve stimulation; comparisons of different surgical methods for benign prostatic hyperplasia, such as classic transurethral resection of the prostate, enucleation, water vapor ablation, and prostatic artery embolization, etc.) and surgical complications (including major surgical complications, systemic complications, sepsis, sepsis-related encephalopathy, venous thromboembolism and pulmonary embolism, etc.), prognosis and its influencing factors and reproductive effects (including IVF/ICSI treatment), etc. The research is planned to span 36 months, allowing sufficient time for detailed data analysis, synthesis of findings, and dissemination of results to the scientific community and public.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 20186 | Endometriosis, subclinical cardiac remodeling, and cardiovascular risk: mechanistic insights from cardiac magnetic resonance and mediation analysis | Yanzhi Feng (+6) | 2026 | Reproductive Biology and Endocrinology |
Enabling scientific discoveries that improve human health