| Title: | Understanding the molecular and clinical ethology of cardiac arrhythmia and cardiomyopathy. |
| Lead Institution: | Amsterdam UMC Research BV |
| Principal investigator: |
Application 176602
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About
Heart failure and heart rhythm abnormalities are diseases that can cause harm and death. We do not fully understand how these diseases work, and why some people develop them at early age while others reach 80 years with no heart problems. Using the large cohort of participant from the UK Biobank, we will investigate how genes, proteins, and other markers contribute to heart failure and heart rhythm abnormalities. We will also use these data to make new tools for earlier prediction of these disorders. We hope that our research will i) help us better understand how these diseases work, ii) help us find new medicines and iii) help us better identify people who might need earlier treatment.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 20165 | Multi-trait polygenic risk scores improve genomic prediction of atrial fibrillation across diverse ancestries | Poeya Haydarlou (+14) | 2026 | Nature Communications |
Enabling scientific discoveries that improve human health