| Title: | Examining the Relationships Between Genetic Risk, Cardiovascular Risk Factors, Socioeconomic Status, and Cardiovascular Events: UK Biobank Study |
| Lead Institution: | University of California, San Francisco |
| Principal investigator: |
Application 117192
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About
This research project will evaluate independent, mediators, interactions, and associations between socioeconomic status with Life's Essential 8 scores (LE8) and genetic predisposition through Polygenic Risk Scores on the risk of cardiovascular related outcomes and all-cause mortality. The purpose of this study is to analyze the mediating effect of socioeconomic status and LE8 for optimal cardiovascular health and associations between Life's Essential 8 scores with SES and polygenic risk scores to determine risk of cardiovascular related events. The public health impact of this study will help determine which SES groups are most at risk for cardiovascular related events based on income, education, and residence. This study will help address gaps in between SES status and achieving optimal cardiovascular health to prevent cardiovascular related events and/or death.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 17961 | The Role of Socioeconomic Status in the Association between Genetic Predisposition and Cardiovascular Events: A UK Biobank Study | Saigeetha Bhaskar (+3) | 2026 | The American Journal of Cardiology |
Enabling scientific discoveries that improve human health