| Title: | Investigating the influence of physical activity intensity level on arterial stiffness response in hypertension: A UK biobank participant-based study |
| Journal: | Next Research |
| Published: | 1 Sep 2025 |
| DOI: | https://doi.org/10.1016/j.nexres.2025.100729 |
Publication 16054
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Abstract
Introduction Hypertension is a significant global public health issue, with arterial stiffness identified as a crucial factor in its pathogenesis. While physical activity is recognized for enhancing vascular health, the impact of varying amounts of physical activity on arterial stiffness in hypertensive persons remains ambiguous. Methods This cross-sectional study examined 5940 hypertensive individuals from the UK Biobank. Participants were categorized into light, moderate, and vigorous physical activity (PA) groups according to self-reported activity duration and accessible accelerometer data. Arterial stiffness was assessed using the Arterial Stiffness Index (ASI) derived from photoplethysmography-based pulse wave analysis. Group disparities in ASI were evaluated with one-way ANOVA Results No statistically significant changes in arterial stiffness were detected among the three physical activity intensity groups (F2, 812 = 2.39, p = 0.093, η²=0.006). The effect size was small, indicating negligible practical differences among physical activity intensities. Conclusions In hypertensive individuals of the UK Biobank, the intensity of physical activity did not exhibit a significant association with arterial stiffness. Future long-term research employing objective physical activity assessments and accounting for lifestyle factors such as nutrition, sleep, and stress are necessary.</p>
4 Authors
- Opeyemi O Adeloye
- Jeff Gagnon
- Elizabeth M. Mullin
- Samuel Headley
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