| Title: | The 24-Hour Movement Behavior Composition and the Risk of Dementia |
| Journal: | Sage Open Aging |
| Published: | 4 Aug 2025 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/40766877/ |
| DOI: | https://doi.org/10.1177/30495334251361293 |
Publication 16035
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Abstract
Objectives: This study examined the relationship between the 24-hour movement behavior composition-including sleep, sedentary time, light physical activity, and moderate-to-vigorous physical activity-and dementia risk.</p>
Methods: 93,781 participants (mean age: 62 years) from the UK Biobank were studied. The average daily time spent in each movement behavior was determined using accelerometers. Incident cases of dementia were identified over an average 9.6-year follow-up. Cox proportional hazards models with compositional covariates assessed the associations of interest.</p>
Results: Relative time in moderate-to-vigorous and light physical activity were negatively associated with dementia risk while relative time in sedentary behavior was positively associated with dementia risk. Each 15 min/day reallocation of time from sedentary behavior into sleep, sedentary behavior, or physical activity reduced dementia risk by 2% to 5%.</p>
Conclusions: The time-use composition of movement behaviors across the 24-hour day influences dementia risk.</p>
3 Authors
- Margarita Liubetskaya
- Marcus Vinicius Veber Lopes
- Ian Janssen
1 Application
| Application ID | Title |
|---|---|
| 120034 | Associations Between the 24-Hour Movement Behaviour Composition and Dementia |
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