| Title: | Dual Cohort Insights Into Accelerometer-Derived Weekend Warrior Physical Activity and Its Impact on Mortality |
| Journal: | Journal of the American Heart Association |
| Published: | 26 May 2025 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/40417791/ |
| DOI: | https://doi.org/10.1161/jaha.124.039852 |
Publication 15232
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Abstract
BACKGROUND: Although guidelines on physical activity recommend at least 150 minutes of moderate-to-vigorous exercise weekly for optimal health outcomes, the distinction between concentrated and evenly distributed activity patterns remains unclear. We explored the relationships between accelerometer-measured weekend warrior and evenly spread moderate-to-vigorous physical activity (MVPA) and the risks of all-cause, cardiovascular disease, and cancer mortality.</p>
METHODS: Accelerometer-based physical activity data from the UK Biobank (Cohort 1 [June 8, 2013-December 30, 2015]: 89 488 individuals) and the US National Health and Nutrition Examination Survey (Cohort 2 [2003-2006]: 6198 individuals) were included in this study. Accelerometer-derived MVPA was categorized as inactive, weekend warrior, or regularly active. Activity patterns were further evaluated using population-specific MVPA thresholds at the 25th, 50th, and 75th percentiles. All-cause, cardiovascular disease, and cancer mortalities were ascertained from death certificates.</p>
RESULTS: Over median follow-up periods of 6.9 and 6.0 years, we recorded 3759 and 1404 deaths in Cohorts 1 and 2, respectively. Compared with inactivity, both activity patterns, at ≥150 minutes of MVPA per week, were correlated with similarly lower risks of all-cause, cardiovascular disease, and cancer mortality at any threshold in both cohorts. These findings were consistent at the 25th percentile threshold and higher for MVPA per week.</p>
CONCLUSIONS: Physical activity concentrated within 1 to 2 days is associated with reduced risks of all-cause, cardiovascular, and cancer mortality, with benefits comparable with those of activity spread more evenly throughout the week.</p>
18 Keywords
- Accelerometry
- Adult
- Aged
- Cardiovascular Diseases
- Cause of Death
- Exercise
- Female
- Humans
- Male
- Middle Aged
- Neoplasms
- Nutrition Surveys
- Risk Assessment
- Risk Factors
- Sedentary Behavior
- Time Factors
- United Kingdom
- United States
10 Authors
- Rui Ren
- Wenxu Wang
- Qitong Liu
- Xingyue Ye
- Linze Xi
- Ru Zhang
- Liying Wang
- Yao Zhang
- Yanan Ma
- Difei Wang
1 Application
| Application ID | Title |
|---|---|
| 147427 | Study of Multifactorial Effects on Aging and Diseases in the Elderly Population and Construction of a Population-based Early Aging Warning Model |
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