| Title: | Associations of road traffic noise with cardiovascular diseases and mortality: Longitudinal results from UK Biobank and meta-analysis |
| Journal: | Environmental Research |
| Published: | 29 Mar 2022 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/35358546/ |
| DOI: | https://doi.org/10.1016/j.envres.2022.113129 |
Publication 13893
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Abstract
BACKGROUND: Epidemiological evidence suggests potential associations of road traffic noise exposure with cardiovascular disease (CVD) and mortality, but uncertainty remains.</p>
OBJECTIVES: We examined the association of road traffic noise with the risk of CVD and mortality in a large longitudinal cohort study and meta-analysis.</p>
METHODS: We analyzed 342, 566 participants from the UK Biobank who were free of CVD at baseline and had complete covariate data. We also performed a meta-analysis of road traffic noise effects on CVD and mortality by including qualified cohort studies published before April 2021.</p>
RESULTS: After adjustment for potential confounders, the odds for the risk of stroke, CVD, and all-cause mortality increased by 1.07 (95%CI: 1.01-1.13, P = 0.019), 1.13 (95%CI: 1.04-1.22, P = 0.003) and 1.08 (95%CI: 1.04-1.12, P < 0.001) times per 10 dB increases in road traffic noise, respectively. Among men, high road traffic noise exposure was significantly associated with an increased risk in stroke (HR = 1.08 per 10 dB increase, 95%CI: 1.00-1.16, P = 0.043), CVD (HR = 1.12 per 10 dB increase, 95%CI: 1.02-1.23, P = 0.020) and all-cause mortality (HR = 1.12 per 10 dB increase, 95%CI: 1.07-1.17 P < 0.001), whereas we did not find a significant association in women. The meta-analysis showed that road traffic noise exposure was significantly associated with a high risk of stroke (risk ratio [RR]: 1.06, 95% CI: 1.02-1.11), CVD mortality (RR: 1.03, 95% CI: 1.00-1.05), all-cause mortality (RR: 1.05, 95% CI: 1.02-1.07).</p>
CONCLUSIONS: This study provides more evidence of increased risk of stroke, CVD, and all-cause mortality in association with exposure to road traffic noise pollution, especially in men.</p>
10 Keywords
- Biological Specimen Banks
- Cardiovascular Diseases
- Environmental Exposure
- Female
- Humans
- Longitudinal Studies
- Male
- Noise, Transportation
- Stroke
- United Kingdom
8 Authors
- Guang Hao
- Lei Zuo
- Xueqiong Weng
- Qiaoyuan Fei
- Zugui Zhang
- Li Chen
- Zengwu Wang
- Chunxia Jing
1 Application
| Application ID | Title |
|---|---|
| 69597 | Association of Noise Pollution and Cardiometabolic Disease |
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