| Title: | Accelerometer-derived physical activity and mortality in individuals with type 2 diabetes |
| Journal: | Nature Communications |
| Published: | 17 Jun 2024 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/38886353/ |
| DOI: | https://doi.org/10.1038/s41467-024-49542-0 |
Publication 11842
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Abstract
Physical activity (PA) has been shown to reduce diabetes mortality, but largely based on imprecise self-reported data, which may hinder the development of related recommendations. Here, we perform a prospective cohort study of 4003 individuals with type 2 diabetes (T2D) from the UK Biobank with a median follow-up of 6.9 years. Duration and intensity of PA are measured by wrist-worn accelerometers over a 7-day period. We observe L-shaped associations of longer duration of PA, regardless of PA intensity, with risks of all-cause and cancer mortality, as well as a negatively linear association with cardiovascular disease mortality. 18.8%, 28.0%, and 31.1% of deaths are attributable to the lowest level of light-intensity PA, moderate-intensity PA, and vigorous-intensity PA, respectively. Collectively, our findings provide insights for clinical guidelines that should highlight the potential value of adherence to greater intensity and duration of PA for patients with T2D.</p>
13 Keywords
- Accelerometry
- Adult
- Aged
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Exercise
- Female
- Humans
- Male
- Middle Aged
- Neoplasms
- Prospective Studies
- United Kingdom
7 Authors
- Zhi Cao
- Jiahao Min
- Han Chen
- Yabing Hou
- Hongxi Yang
- Keyi Si
- Chenjie Xu
1 Application
| Application ID | Title |
|---|---|
| 79095 | Dietary patterns and lifestyle-related factors with human immunity and multimorbidity burden |
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