| Title: | Cardiovascular-kidney-metabolic health and all-cause and cause-specific mortality in the UK Biobank cohort |
| Lead Institution: | First Affiliated Hospital of Jinan University |
| Principal investigator: |
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About
There is a high burden of poor cardiovascular-kidney metabolic health in general population, which affects nearly all organ systems and has potent impact on the incidence of cardiovascular disease. More guidance is needed on definitions, staging, prediction strategies, and algorithms for the prevention and treatment of cardiovascular-kidney-metabolic (CKM) syndrome to optimize CKM health across diverse clinical and community settings. Regrettably, there have been limited efforts to translate individual cardiovascular and kidney risk profiles into a visual tool and explore their prognostic roles in long-term outcomes among the general population. In our study, we will use data from UK Biobank cohort to establish a scoring system for CKM consisting of a series of risk factors. Achieving optimal CKM control were associated with lower risk of mortality and longer life expectancy.2 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 15771 | Association between adherence to the EAT-Lancet diet and risk of microvascular complications in type 2 diabetes: A cohort study | Zenghui Zhang (+8) | 2025 | Diabetes Obesity and Metabolism |
| 16151 | Cognitive reserve, genetic risk, and lifestyle in the incidence and progression of type 2 diabetes: A large community-based longitudinal study | Shaojie Han (+7) | 2025 | Diabetes Obesity and Metabolism |
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