| Title: | The risk of cardiac-cerebral vascular diseases: unravelling the interplay of lifestyle, environmental exposures, and genetics |
| Lead Institution: | Huazhong University of Science and Technology |
| Principal investigator: |
Application 162275
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
About
1 Aims Our research project is dedicated to unravelling the intricate relationships between genetics, lifestyle, and the environment in shaping health outcomes, with a specific focus on cardiac-cerebral vascular diseases. We aim to understand why some individuals are more resilient to these diseases than others and why certain groups are disproportionately affected. Our primary objective is to provide personalized health guidance based on these insights, improving the prevention and management of cardiac-cerebral vascular diseases. 2 Scientific rationale Cardiac-cerebral vascular diseases are multifaceted conditions influenced by a web of factors, encompassing our genes, lifestyle choices, and surrounding environment. By amassing data from a diverse and extensive cohort of individuals, we aspire to illuminate the interconnectedness of these factors. Through a comprehensive examination of these components, our goal is to identify the most effective strategies for achieving and sustaining cardiac-cerebral vascular and cerebral health. 3 Project duration This project is expected to span a duration of three years. 4 Public health impact The impact of this work is far-reaching and multifaceted, contributing to public health in several key ways: 4.1 Personalized health advice Our research will empower the development of personalized health recommendations based on an individual's genetic profile. This will enable people to make informed choices for their well-being, particularly in the context of cardiac-cerebral vascular diseases. 4.2 Healthier environments Findings from our research will inform initiatives aimed at creating cleaner and safer living environments. This broader impact on environmental health will enhance public well-being. 4.3 Health awareness If certain habits or factors are identified as detrimental to health, our research will raise awareness, prompting individuals to make healthier choices and reducing the burden of cardiac-cerebral vascular diseases. In summary, this research holds great promise for improving public health, advancing personalized medicine, informing environmental policies, and fostering a broader understanding of how lifestyle, environment, and genetics collectively influence cardiac-cerebral vascular diseases. Ultimately, this research project has the potential to enhance the well-being of individuals and communities, addressing a key public interest requirement for better cardiac-cerebral vascular health and a healthier society.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 16822 | Associations of sleep patterns and genetic risk with risk of incident schizophrenia: A prospective cohort study of 294,856 participants | Shenrui Li (+3) | 2025 | Journal of Affective Disorders |
Enabling scientific discoveries that improve human health