| Title: | Integrating pan-omics for a better risk stratification of cardiovascular diseases |
| Lead Institution: | Zhongshan Hospital Affiliated to Fudan University |
| Principal investigator: |
Application 133572
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About
Our research project aims to improve the way we understand and predict the risk of cardiovascular diseases, which are conditions affecting the heart and blood vessels. We want to combine different types of information, like your medical history, genetic makeup, and even images of your heart, to create a more accurate picture of your risk for these diseases. Why are we doing this? Cardiovascular diseases are a big health concern worldwide, causing a lot of sickness and even death. The methods we use right now to predict who might get these diseases aren't always perfect. That means some people might not get the right treatment in time, while others might get treatment they don't actually need. We're using a new way of looking at data called "pan-omics." This means we're taking lots of different pieces of information, like your genes, how your body's molecules work, and even images of your heart, and putting them all together. By doing this, we hope to find better ways of knowing who is at high risk for cardiovascular diseases. Our project will last for a certain amount of time, during which we will collect and analyze a lot of data. We will use computer programs that are really good at finding patterns in big sets of information. These patterns could help us understand why some people are more likely to have heart problems than others. But it's not just about science. Our research wants to make a real impact on people's lives. By getting a better idea of who might be at risk, doctors can offer more personalized care. This could mean catching problems earlier and helping people make healthier choices. It might also save money for healthcare systems, making sure resources are used where they're needed most. In short, we're trying to make it easier for doctors to figure out who might be at risk for heart and blood vessel problems. By using new methods and lots of different types of information, we want to improve healthcare and help more people live healthier lives.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 15429 | Association of phenotypic aging, lifestyle, and genetic risk with incidence of atrial fibrillation: A large prospective cohort study in the UK Biobank | Tingting Lin (+5) | 2025 | The journal of nutrition, health & aging |
Enabling scientific discoveries that improve human health