| Title: | Association between a mediterranean lifestyle and Type 2 diabetes incidence: a prospective UK biobank study |
| Journal: | Cardiovascular Diabetology |
| Published: | 4 Oct 2023 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/37794451/ |
| DOI: | https://doi.org/10.1186/s12933-023-01999-x |
| URL: | https://cardiab.biomedcentral.com/counter/pdf/10.1186/s12933-023-01999-x |
Publication 9420
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
Abstract
BackgroundThere is mounting evidence that the Mediterranean diet prevents type 2 diabetes, but little is known about the role of Mediterranean lifestyles other than diet and among non-Mediterranean populations. This work aimed to examine the association between a comprehensive Mediterranean-type lifestyle and type 2 diabetes incidence in a British adult population.MethodsWe used data from 112,493 individuals free of cardiovascular disease and type 2 diabetes mellitus, aged 40-69 years, from the UK Biobank cohort, who were followed from 2009 to 2010 to 2021. The Mediterranean lifestyle was assessed through the 25-item MEDLIFE index, which comprises three blocks: (a) "Mediterranean food consumption", (b) "Mediterranean dietary habits", (c) "Physical activity, rest, social habits, and conviviality". Diabetes incidence was obtained from clinical records. Cox proportional-hazards regression models were used to analyze associations and adjusted for the main potential confounders.ResultsAfter a median follow-up of 9.4 years, 2,724 cases of type 2 diabetes were ascertained. Compared to the first quartile of MEDLIFE adherence, the hazard ratios (95% confidence interval) for increasing quartiles of adherence were 0.90 (0.82-0.99), 0.80 (0.72-0.89) and 0.70 (0.62-0.79) (p-trend < 0.001). All three blocks of MEDLIFE were independently associated with lower risk of diabetes.ConclusionsHigher adherence to the MEDLIFE index was associated with lower risk of type 2 diabetes in the UK Biobank. A Mediterranean-type lifestyle, culturally adapted to non-Mediterranean populations, could help prevent diabetes.</p>
7 Authors
- Javier Maroto-Rodriguez
- Rosario Ortolá
- Adrián Carballo-Casla
- Víctor Iriarte-Campo
- Miguel Ángel Salinero-Fort
- Fernando Rodríguez-Artalejo
- Mercedes Sotos-Prieto
1 Application
| Application ID | Title |
|---|---|
| 80773 | The effect of novel Healthy Lifestyle Scores in the association of frailty and chronic pain with risk of cancer and CVD, as well as all-cause and cause-specific mortality in British adults |
Enabling scientific discoveries that improve human health