| Title: | Mobile Phone Use and Risks of Overall and 25 Site-Specific Cancers: A Prospective Study from the UK Biobank Study. |
| Journal: | Cancer Epidemiology Biomarkers & Prevention |
| Published: | 23 Oct 2023 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/37870426/ |
| DOI: | https://doi.org/10.1158/1055-9965.epi-23-0766 |
Publication 9343
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Abstract
BACKGROUND: The association between mobile phone use and incident cancers remains uncertain. We aimed to investigate the relationships of mobile phone use with incident overall and 25 site-specific cancers in men and women.</p>
METHODS: A total of 431,861 participants ages 38 to 73 years without prior cancers were included from the UK Biobank. Of these, 46.7% were male. Participants who used a mobile phone at least once per week to make or receive calls were defined as mobile phone users. The study outcomes were incident overall and 25 site-specific cancers.</p>
RESULTS: During a median follow-up of 10.7 years, 35,401 (17.5%) men and 30,865 (13.4%) women developed overall cancer. Mobile phone use was significantly associated with higher risks of incident overall cancer [HR, 1.09; 95% confidence interval (CI): 1.06-1.12], nonmelanoma skin cancer (NMSC; HR, 1.08; 95% CI: 1.03-1.14), urinary tract cancer (HR, 1.18; 95% CI:1.05-1.32), and prostate cancer (HR, 1.19; 95% CI: 1.13-1.25) in men, and incident overall cancer (HR, 1.03; 95% CI: 1.00-1.06), NMSC (HR, 1.07; 95% CI: 1.01-1.13), and vulva cancer (HR, 1.74; 95% CI: 1.00-3.02) in women, but not with other cancers. Among mobile phone users, there was a dose-response relationship of length of mobile phone use with incident NMSC in men and women, and prostate cancer in men (all Ptrend < 0.05).</p>
CONCLUSIONS: There was a dose-response relationship of length of mobile phone use with incident NMSC in men and women, and prostate cancer in men.</p>
IMPACT: Our findings underscore the importance of limiting mobile phone use or keeping a distance from mobile phone for primary prevention of NMSC and prostate cancer.</p>
10 Authors
- Yanjun Zhang
- Yuanyuan Zhang
- Ziliang Ye
- Sisi Yang
- Mengyi Liu
- Qimeng Wu
- Chun Zhou
- Panpan He
- Xiaoqin Gan
- Xianhui Qin
1 Application
| Application ID | Title |
|---|---|
| 73201 | Identification of residual risks of non-infectious chronic diseases |
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