| Title: | Sleep patterns and risks of incident cardiovascular disease and mortality among people with type 2 diabetes: a prospective study of the UK Biobank |
| Journal: | Diabetology & Metabolic Syndrome |
| Published: | 11 Jan 2024 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/38212811/ |
| DOI: | https://doi.org/10.1186/s13098-024-01261-8 |
| URL: | https://dmsjournal.biomedcentral.com/counter/pdf/10.1186/s13098-024-01261-8 |
Publication 8962
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Abstract
BackgroundTo explore the relationship between sleep patterns and cardiovascular disease (CVD) incidence and mortality risk in a population with type 2 diabetes through a UK Biobank sample.MethodsA total of 6860 patients with type 2 diabetes were included in this study. Five sleep factors (including Chronotype, sleep duration, insomnia, daytime sleepiness, and snoring) were collected as a questionnaire. The calculation generates a sleep score of 0-5, and then three sleep patterns were defined based on the sleep scores: poor sleep pattern (0-2), Intermediate sleep pattern (3-4), and healthy sleep pattern (5). HRs and 95% confidence intervals were calculated by multivariate COX proportional risk model adjustment. Restricted cubic splines were used to validate linear associations between sleep scores CVD events.ResultsOur results found a reduced risk of CVD events in individuals with healthy sleep patterns compared to participants with poor sleep patterns. CVD Mortality (HR, 0.690; 95% CI 0.519-0.916), ASCVD (Atherosclerosis CVD) (HR, 0.784; 95% CI 0.671-0.915), CAD (Coronary Artery Disease) (HR, 0.737; 95% CI 0.618-0.879), PAD (Peripheral Arterial Disease) (HR, 0.612; 95% CI 0.418-0.896), Heart Failure (HR, 0.653; 95% CI 0.488-0.875). Restricted cubic spline responded to a negative linear correlation between sleep scores and CVD Mortality, ASCVD, CAD, PAD, and Heart Failure.ConclusionsHealthy sleep patterns are significantly associated with a reduced risk of CVD Mortality, ASCVD, CAD, PAD, and Heart Failure in the diabetes population.</p>
9 Authors
- Jinxia Hu
- Xuanyang Wang
- Licheng Cheng
- Keke Dang
- Zhu Ming
- Xinmiao Tao
- Xiaoqing Xu
- Shuvan Kumar Sarker
- Ying Li
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