| Title: | Periodontal disease in people with a history of psychosis: Results from the UK biobank population-based study |
| Journal: | Community Dentistry And Oral Epidemiology |
| Published: | 18 Oct 2022 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/36258297/ |
| DOI: | https://doi.org/10.1111/cdoe.12798 |
| URL: | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cdoe.12798 |
Publication 8115
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Abstract
OBJECTIVES: To test the hypotheses that: (1) Prevalence of periodontal disease would be higher in people with a history of psychosis when compared to the general population and (2) Demographic, life-style related factors and co-morbid medical conditions would predict periodontal disease in people experiencing psychosis. METHODS: The authors performed cross-sectional analysis of baseline data from the UK Biobank study (2007-2010), identifying cases with psychosis using clinical diagnosis, antipsychotic medication, and self-report. Demographic (age, gender, ethnicity, socioeconomic status), lifestyle-related(BMI, blood pressure, smoking and alcohol intake, physical activity) and physical co-morbidities (cancer, cardiovascular, respiratory, inflammatory disease and metabolic conditions) were included as potential risk factors for periodontal disease among people with a history of psychosis using logistic regression analyses. The analysis sample included 502,505 participants. RESULTS: Risk of periodontal disease was higher in people with psychosis, regardless of how cases were identified. Patients with a clinical diagnosis had the highest proportion of periodontal disease compared to the general population (21.3% vs. 14.8%, prevalence ratio 1.40, 95% CI: 1.26-1.56). Older and female cases were more likely to experience periodontal disease. Lifestyle factors (smoking) and comorbidities (cardiovascular, cancer or respiratory disease) were associated with periodontal disease among people with a history of psychosis. CONCLUSIONS: The findings suggest that periodontal disease is more common in people with a history of psychosis, compared to the general population. Prevention and early diagnosis of periodontal disease should be a priority for oral health promotion programmes, which should also address modifiable risk factors like smoking which also contribute to co-morbid systemic disease.7 Authors
- Jing Kang
- Jasper Palmier-Claus
- Jianhua Wu
- David Shiers
- Harriet Larvin
- Tim Doran
- Vishal R. Aggarwal
1 Application
| Application ID | Title |
|---|---|
| 54633 | Investigating the association between periodontal disease and systemic diseases |
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