| Title: | Prioritization of COVID-19 risk factors in July 2020 and February 2021 in the UK |
| Journal: | Communications Medicine |
| Published: | 30 Mar 2023 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/36997659/ |
| DOI: | https://doi.org/10.1038/s43856-023-00271-3 |
| URL: | https://www.nature.com/articles/s43856-023-00271-3.pdf |
Publication 7886
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Abstract
BackgroundRisk for COVID-19 positivity and hospitalization due to diverse environmental and sociodemographic factors may change as the pandemic progresses.MethodsWe investigated the association of 360 exposures sampled before COVID-19 outcomes for participants in the UK Biobank, including 9268 and 38,837 non-overlapping participants, sampled at July 17, 2020 and February 2, 2021, respectively. The 360 exposures included clinical biomarkers (e.g., BMI), health indicators (e.g., doctor-diagnosed diabetes), and environmental/behavioral variables (e.g., air pollution) measured 10-14 years before the COVID-19 time periods.ResultsHere we show, for example, "participant having son and/or daughter in household" was associated with an increase in incidence from 20% to 32% (risk difference of 12%) between timepoints. Furthermore, we find age to be increasingly associated with COVID-19 positivity over time from Risk Ratio [RR] (per 10-year age increase) of 0.81 to 0.6 (hospitalization RR from 1.18 to 2.63, respectively).ConclusionsOur data-driven approach demonstrates that time of pandemic plays a role in identifying risk factors associated with positivity and hospitalization.3 Authors
- Sivateja Tangirala
- Braden T. Tierney
- Chirag J. Patel
1 Application
| Application ID | Title |
|---|---|
| 22881 | Causal relationships between infectious and non-communicable/ common disease. |
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