| Title: | Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence |
| Journal: | Nature Genetics |
| Published: | 22 May 2017 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/28530673/ |
| DOI: | https://doi.org/10.1038/ng.3869 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665562 |
| Citations: | 422 (60 in last 2 years) as of 8 Aug 2024 |
Publication 724
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Abstract
Danielle Posthuma and colleagues perform a large meta-analysis for intelligence and determine genetic overlap with several neuropsychiatric and metabolic traits. They find 15 new significant loci and implicate 40 new genes, most of which are predominantly expressed in the brain.</p>
18 Keywords
- Adolescent
- Adult
- Aged
- Brain
- Child
- Child, Preschool
- Female
- Genome-Wide Association Study
- Humans
- Infant
- Intelligence
- Linkage Disequilibrium
- Male
- Middle Aged
- Nerve Tissue Proteins
- Polymorphism, Single Nucleotide
- White People
- Young Adult
30 Authors
- Suzanne Sniekers
- Sven Stringer
- Kyoko Watanabe
- Philip R Jansen
- Jonathan R I Coleman
- Eva Krapohl
- Erdogan Taskesen
- Anke R Hammerschlag
- Aysu Okbay
- Delilah Zabaneh
- Najaf Amin
- Gerome Breen
- David Cesarini
- Christopher F Chabris
- William G Iacono
- M Arfan Ikram
- Magnus Johannesson
- Philipp Koellinger
- James J Lee
- Patrik K E Magnusson
- Matt McGue
- Mike B Miller
- William E R Ollier
- Antony Payton
- Neil Pendleton
- Robert Plomin
- Cornelius A Rietveld
- Henning Tiemeier
- Cornelia M van Duijn
- Danielle Posthuma
1 Application
| Application ID | Title |
|---|---|
| 16406 | Causes of individual differences in cognitive and mental health |
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