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To use genomic approaches to identify risk factors for a set of common diseases of particular importance in development and aging. In particular, we will focus on metabolic phenotypes (disease like type 2 diabetes, and phenotypes like BMI), reproductive phenotypes (like number of children and age at menarche), and common causes of death (cancer, heart disease, and neurological disease).
Jimmy Z Liu, Yaniv Erlich & Joseph K Pickrell Case control association mapping by proxy using family history of disease.Nat Genet. 2017 Mar;49(3):325-331. doi: 10.1038/ng.3766