| Title: | Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk |
| Journal: | Nature Genetics |
| Published: | 30 Jan 2017 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/28135244/ |
| DOI: | https://doi.org/10.1038/ng.3768 |
| URL: | https://research.vu.nl/files/288420169/ng.3768_Genome-wide_association_analysis_identifies_novel_blood_pressure_loci_and_offers_biological_insights_into_cardiovascular_risk.pdf |
| Citations: | 498 (97 in last 2 years) as of 8 Aug 2024 |
Publication 585
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Abstract
Mark Caulfield, Paul Elliott and colleagues use data from the UK Biobank to perform genome-wide association analysis for blood pressure traits. They identify and validate 107 novel loci and highlight new biological pathways for potential therapeutic intervention for hypertension.</p>
59 Authors
- Helen R Warren
- Evangelos Evangelou
- Claudia P Cabrera
- He Gao
- Meixia Ren
- Borbala Mifsud
- Ioanna Ntalla
- Praveen Surendran
- Chunyu Liu
- James P Cook
- Aldi T Kraja
- Fotios Drenos
- Marie Loh
- Niek Verweij
- Jonathan Marten
- Ibrahim Karaman
- Marcelo P Segura Lepe
- Paul F O'Reilly
- Joanne Knight
- Harold Snieder
- Norihiro Kato
- Jiang He
- E Shyong Tai
- M Abdullah Said
- David Porteous
- Maris Alver
- Neil Poulter
- Martin Farrall
- Ron T Gansevoort
- Sandosh Padmanabhan
- Reedik Mägi
- Alice Stanton
- John Connell
- Stephan J L Bakker
- Andres Metspalu
- Denis C Shields
- Simon Thom
- Morris Brown
- Peter Sever
- Tõnu Esko
- Caroline Hayward
- Pim van der Harst
- Danish Saleheen
- Rajiv Chowdhury
- John C Chambers
- Daniel I Chasman
- Aravinda Chakravarti
- Christopher Newton-Cheh
- Cecilia M Lindgren
- Daniel Levy
- Jaspal S Kooner
- Bernard Keavney
- Maciej Tomaszewski
- Nilesh J Samani
- Joanna M M Howson
- Martin D Tobin
- Patricia B Munroe
- Georg B Ehret
- Louise V Wain
1 Application
| Application ID | Title |
|---|---|
| 236 | Genome-wide association study of blood pressure. |
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