| Title: | Dose-Response Associations of Dietary Inflammatory Potential With Health Outcomes: A Prospective Cohort Study of 198,265 UK Biobank Participants |
| Journal: | Current Problems in Cardiology |
| Published: | 29 Apr 2023 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/37121456/ |
| DOI: | https://doi.org/10.1016/j.cpcardiol.2023.101774 |
| Citations: | 5 (5 in last 2 years) as of 8 Aug 2024 |
Publication 11392
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Abstract
To investigate the dose-response associations of dietary inflammatory potential with all-cause mortality and incident cardiovascular disease (CVD) and cancer.</p>
METHODS: This was a prospective cohort study of 198,265 UK Biobank participants who completed at least 1 dietary assessment. A web based 24 hours recall questionnaire was used to derive the energy-adjusted dietary inflammatory index (E-DII). All-cause mortality and incident CVD and cancer ascertained from linked records.</p>
RESULTS: After adjusting for socio-demographic and lifestyle factors, there were J-shaped associations of E-DII with all-cause mortality and CVD, and a relatively linear association with cancer. When E-DII was <0, E-DII was not associated with any of the outcomes. When E-DII was ≥0, the linear associations were strongest in all-cause mortality (HR 1.09, 95% CI, 1.05-1.13), followed by CVD (HR 1.06, 95% CI, 1.03-1.09), and cancer (HR 1.03, 95%,CI, 1.01-1.05).</p>
CONCLUSION: Dietary inflammatory potential was associated with mortality and CVD primarily when the diet is proinflammatory.</p>
12 Authors
- Frederick K Ho
- Michael D Wirth
- Solange Parra-Soto
- Jirapitcha Boonpor
- Ziyi Zhou
- Fanny Petermann-Rocha
- Shinya Nakada
- Katherine M Livingstone
- John C Mathers
- Jill P Pell
- James R Hébert
- Carlos Celis-Morales
1 Application
| Application ID | Title |
|---|---|
| 7155 | Epidemiology of mental health, cognitive function, pain and cardiometabolic disease. |
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