| Title: | Multidimensional Assessment of Subjective Well-being and Risk of Dementia: Findings from the UK Biobank Study |
| Journal: | Journal of Happiness Studies |
| Published: | 29 Dec 2022 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/37153640/ |
| DOI: | https://doi.org/10.1007/s10902-022-00613-3 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10162491 |
Publication 10861
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Abstract
This study aimed to examine the associations between subjective well-being (SWB) and risk of all-cause dementia, Alzheimer's disease (AD), and vascular dementia (VD). We adopted a multidimensional approach to SWB that included the level and breadth of SWB, the latter indicating the extent to which SWB spreads across life domains. Participants (N = 171,197; mean age = 56.78; SD = 8.16 years) were part of the UK Biobank and were followed up to 8.78 years. Domain-general and domain-specific SWB were measured by single items, and the breadth of SWB was indexed with a cumulative score of satisfaction across domains. Dementia incidence was ascertained through hospital and death records. Cox regression was used to examine the association between SWB indicators and risk of all-cause dementia, AD, and VD. General happiness, health and family satisfaction, and satisfaction breadth (satisfaction in multiple domains) were associated with lower risk of all-cause dementia. The associations held after accounting for socio-demographics, health, behavioral, and economic covariates, and depressive symptoms. Health satisfaction and the breadth of satisfaction were also associated with lower risk of AD and VD, with a pattern of slightly stronger associations for VD compared to AD. Some life domains (e.g., health) may be more fruitfully targeted to promote well-being and help protect against dementia, but it is also important to enhance well-being across multiple domains to maximize the protective effects.</p>
7 Authors
- Xianghe Zhu
- Martina Luchetti
- Damaris Aschwanden
- Amanda A. Sesker
- Yannick Stephan
- Angelina R. Sutin
- Antonio Terracciano
1 Application
| Application ID | Title |
|---|---|
| 57672 | Linking psychological well-being measures to brain and health biomarkers to understand aging and risk of dementia |
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