| Title: | Dietary patterns, malnutrition, muscle loss and sarcopenia in cancer survivors: findings from the UK Biobank |
| Journal: | Journal of Cancer Survivorship |
| Published: | 20 Jul 2023 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/37468793/ |
| DOI: | https://doi.org/10.1007/s11764-023-01428-8 |
| URL: | https://link.springer.com/content/pdf/10.1007/s11764-023-01428-8.pdf |
| Citations: | 6 (6 in last 2 years) as of 8 Aug 2024 |
Publication 10519
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Abstract
PurposeTo identify dietary patterns derived from protein, polyunsaturated fatty acids (PUFA) and vitamin D and examine associations with malnutrition, low muscle mass and sarcopenia in cancer survivors.MethodsThis cross-sectional study included cancer survivors (n = 2415) from the UK Biobank (age [mean ± SD] 59.7 ± 7.1 years; 60.7% female). The Oxford WebQ 24-h dietary assessment estimated food and nutrient intakes. Reduced rank regression derived dietary patterns (response variables: protein [g/kg/day], PUFA [g/day] and vitamin D [μg/day]). Adjusted logistic regression analysis examined associations between dietary patterns and malnutrition, low muscle mass and sarcopenia.ResultsThree dietary patterns were identified: (i) 'high oily fish and nuts', characterised by higher oily fish and nuts and seeds intake; (ii) 'low oily fish', characterised by lower oily fish intake and higher potato intake; and (iii) 'meat and dairy', characterised by higher intake of meat, poultry and dairy. Eighteen percent of participants were malnourished, 5% had low muscle mass and 6.5% had sarcopenia. Odds of being malnourished were significantly lower with adherence to a 'high oily fish and nuts' pattern (OR: 0.57; 95% CI: 0.50, 0.65) and 'low oily fish' pattern (OR: 0.81; 95% CI: 0.73, 0.90). The 'meat and dairy' pattern was not associated with malnutrition. No dietary patterns were associated with low muscle mass or sarcopenia.ConclusionsEnergy-rich dietary patterns were associated with lower odds of malnutrition in cancer survivors but did not influence muscle mass or sarcopenia risk.Implications for Cancer SurvivorsBetter understanding of dietary patterns may improve cancer-related outcomes for cancer survivors.</p>
6 Authors
- Annie R Curtis
- Katherine M Livingstone
- Robin M Daly
- Barbara Brayner
- Gavin Abbott
- Nicole Kiss
Enabling scientific discoveries that improve human health