| Title: | Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits |
| Journal: | Nature Genetics |
| Published: | 12 Jun 2017 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/28604731/ |
| DOI: | https://doi.org/10.1038/ng.3888 |
| URL: | https://europepmc.org/articles/pmc5600256?pdf=render |
Publication 7538
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Abstract
Danielle Posthuma and colleagues report a genome-wide association analysis for insomnia complaints in 113,006 individuals from the UK Biobank that identifies associations with variants near seven genes. They find evidence for sex-specific genetic architectures underlying genetic risk for insomnia and genetic correlations between insomnia complaints and psychiatric and metabolic traits.22 Authors
- Anke R Hammerschlag
- Sven Stringer
- Christiaan A de Leeuw
- Suzanne Sniekers
- Erdogan Taskesen
- Kyoko Watanabe
- Tessa F Blanken
- Kim Dekker
- Bart H W te Lindert
- Rick Wassing
- Ingileif Jonsdottir
- Gudmar Thorleifsson
- Hreinn Stefansson
- Thorarinn Gislason
- Klaus Berger
- Barbara Schormair
- Juergen Wellmann
- Juliane Winkelmann
- Kari Stefansson
- Konrad Oexle
- Eus J W Van Someren
- Danielle Posthuma
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