| Title: | Prospective study of sleep duration and glioma risk |
| Journal: | Cancer Causes & Control |
| Published: | 20 May 2021 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/34014383/ |
| DOI: | https://doi.org/10.1007/s10552-021-01447-9 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859696 |
| Citations: | 2 as of 8 Aug 2024 |
Publication 5617
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
Abstract
PurposeBoth long and short sleep duration have been linked with risk of some cancers, but evidence for glioma is lacking.MethodsUsing prospective data from the UK Biobank (UKB), the Nurses' Health Study (NHS), and the Health Professionals Follow-Up Study (HPFS), we examined the association between self-reported hours of sleep and incident glioma in multivariable-adjusted Cox proportional hazards models.ResultsIn the UKB, compared to 7 h, sleep durations of < 7 h (HR = 0.90; 95% CI 0.70-1.16) or > 7 h (HR = 1.05; 95% CI 0.85-1.30) were not significantly associated with glioma risk. Likewise, no significant associations were found between sleep duration and glioma risk in the NHS/HPFS for either < 7 h (HR = 0.93; 95% CI 0.69-1.26) or > 7 h (HR = 1.22; 95% CI 0.94-1.57), compared to 7 h. Results were similar for low-grade and high-grade glioma, did not materially change after lagging 2 years, or after accounting for factors known to disrupt sleep.ConclusionSleep duration was not associated with incident glioma in either the UKB or the NHS/HPFS cohorts.</p>
7 Keywords
- Follow-Up Studies
- Glioma
- Humans
- Proportional Hazards Models
- Prospective Studies
- Risk Factors
- Sleep
7 Authors
- Claudine M. Samanic
- David J. Cote
- Jordan H. Creed
- Meir J. Stampfer
- Molin Wang
- Stephanie A. Smith-Warner
- Kathleen M. Egan
Enabling scientific discoveries that improve human health