| Title: | Diet, Physical Activity, and Disinhibition in Middle-Aged and Older Adults: A UK Biobank Study |
| Journal: | Nutrients |
| Published: | 11 May 2021 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/34064914/ |
| DOI: | https://doi.org/10.3390/nu13051607 |
| URL: | https://www.mdpi.com/2072-6643/13/5/1607/pdf?version=1620737736 |
| Citations: | 5 (2 in last 2 years) as of 8 Aug 2024 |
Publication 4681
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Abstract
Disinhibition is a prominent feature of multiple psychiatric disorders, and has been associated with poor long-term somatic outcomes. Modifiable lifestyle factors including diet and moderate-to-vigorous physical activity (MVPA) may be associated with disinhibition, but their contributions have not previously been quantified among middle-aged/older adults. Here, among N = 157,354 UK Biobank participants aged 40-69, we extracted a single disinhibition principal component and four dietary components (prudent diet, elimination of wheat/dairy/eggs, meat consumption, full-cream dairy consumption). In addition, latent profile analysis assigned participants to one of five empirical dietary groups: prudent-moderate, unhealthy, restricted, meat-avoiding, low-fat dairy. Disinhibition was regressed on the four dietary components, the dietary grouping variable, and self-reported MVPA. In men and women, disinhibition was negatively associated with prudent diet, and positively associated with wheat/dairy/eggs elimination. In men, disinhibition was also associated with consumption of meat and full-cream dairy products. Comparing groups, disinhibition was lower in the prudent-moderate diet (reference) group compared to all other groups. Absolute βs ranged from 0.02-0.13, indicating very weak effects. Disinhibition was not associated with MVPA. In conclusion, disinhibition is associated with multiple features of diet among middle-aged/older adults. Our findings foster specific hypotheses (e.g., early malnutrition, elevated immune-response) to be tested in alternative study designs.</p>
10 Authors
- Lizanne J. S. Schweren
- Daan van Rooij
- Huiqing Shi
- Henrik Larsson
- Alejandro Arias-Vasquez
- Lin Li
- Liv Grimstvedt Kvalvik
- Jan Haavik
- Jan Buitelaar
- Catharina Hartman
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