| Title: | Relationship between multimorbidity, demographic factors and mortality: findings from the UK Biobank cohort |
| Journal: | BMC Med |
| Published: | 10 Apr 2019 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/30967141/ |
| DOI: | https://doi.org/10.1186/s12916-019-1305-x |
Publication 2836
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Abstract
In our study of middle to older aged participants recruited from the general population, multimorbidity was consistently associated with higher all-cause, cancer and vascular mortality, even after adjusting for the effects of lifestyle and demographic factors. Cardiometabolic multimorbidity was noted to have a consistent association with all three clinical outcomes considered, while cancer and cardiometabolic conditions were featured in almost all the most impactful combinations of LTCs for mortality risk. Type of LTCs, as opposed to a number, may have an important role in understanding the relationship between multimorbidity and mortality. Younger participants, especially men, were observed to have a relatively higher risk of mortality with increasing number of LTCs. Further research is needed to study the impact and management of multimorbidity in middle-aged adults, as they may be at higher risk of early death.1 Author
- Jani BD et al.
1 Application
| Application ID | Title |
|---|---|
| 14151 | Exploring multimorbidity in UK Biobank ? patterns of illness reporting and effects of comorbidity and multimorbidity on health outcomes |
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