| Title: | Weekend Warrior Physical Activity, Sedentary Behavior, and Incident Disability in Middle-Aged and Older Adults: A UK Biobank Accelerometer Study |
| Journal: | Geriatrics and Gerontology International |
| Published: | 25 Aug 2026 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/42642715/ |
| DOI: | https://doi.org/10.1111/ggi.70818 |
Publication 20903
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Abstract
AIM: Regular moderate-to-vigorous physical activity (MVPA) is associated with lower risks of functional decline and disability. Whether concentrating MVPA into 1 or 2 days per week-the "weekend warrior" pattern-is associated with disability risk similarly to regularly distributed activity remains unclear, particularly among individuals with high sedentary behavior.</p>
METHODS: We analyzed wrist-worn accelerometer data from 41 225 UK Biobank participants without identifiable baseline disability based on available indicators (mean age 61.6 years; 60.3% women). Participants were classified as inactive (< 150 min/week), weekend warriors (≥ 150 min/week with ≥ 50% accumulated in 1-2 days), or regularly active (≥ 150 min/week but not weekend warriors). Disability was assessed once during follow-up and defined as a self-reported need for assistance with at least one of six activities of daily living because of a health condition. Associations with incident disability were estimated using Cox proportional hazards models for interval-censored outcomes, adjusting for sociodemographic characteristics, lifestyle factors, and baseline health status.</p>
RESULTS: During a median follow-up of 7.7 years, 2589 participants were classified as having disability at follow-up. Compared with inactive individuals, weekend warrior and regularly active patterns were associated with similarly lower disability risk (weekend warrior: HR 0.68, 95% CI 0.61-0.75; regularly active: HR 0.66, 95% CI 0.60-0.73). These associations were observed across sedentary behavior levels.</p>
CONCLUSIONS: Accumulating recommended MVPA within 1 or 2 days per week was associated with disability risk reductions comparable to regularly distributed activity. Flexible activity patterns may help support functional independence and healthy aging.</p>
14 Keywords
- Accelerometry
- Activities of Daily Living
- Aged
- Exercise
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Persons with Disabilities
- Sedentary Behavior
- Time Factors
- UK Biobank
- United Kingdom
4 Authors
- Xuan Zhu
- Heyan Xia
- Tao Sun
- Xiaojun Wang
1 Application
| Application ID | Title |
|---|---|
| 127327 | Novel Statistical Methods for Complex Survival Data with Applications to Disability Development in the Elderly |
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