| Title: | Neuroticism and suicide in a general population cohort: results from the UK Biobank Project |
| Journal: | BJPsych Open |
| Published: | 16 Mar 2018 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/29971148/ |
| DOI: | https://doi.org/10.1192/bjo.2017.12 |
| URL: | ~Ehttps://www.cambridge.org/core/services/aop-cambridge-core/content/view/44D331F8FD8B9EF8D757C7FE2AB005DD/S2056472417000126a.pdf/div-class-title-neuroticism-and-suicide-in-a-general-population-cohort-results-from-the-uk-biobank-project-div.pdf~ |
Publication 13733
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
Abstract
BACKGROUND: Neuroticism has often been linked to suicidal thoughts and behaviour.</p>
AIMS: To examine whether neuroticism is associated with suicide deaths after adjusting for known risks.</p>
METHOD: UK Biobank participants (n = 389 365) were assessed for neuroticism as well as social, demographic and health-related variables at study entry and followed for up to 10 years. Suicide risk was modelled using Cox regression stratified by gender.</p>
RESULTS: Neuroticism increased the risk of suicide in both men (hazard ratio (HR) = 1.15, 95% CI 1.09-1.22) and women (HR = 1.16, 95% CI 1.06-1.27). In a subsample who were assessed for mood disorders, neuroticism remained a significant predictor for women (HR 1.25, 95% CI 1.03-1.51) but not for men.</p>
CONCLUSIONS: Screening and therapeutic interventions for neuroticism may be important for early suicide prevention.</p>
DECLARATION OF INTEREST: None.</p>
5 Authors
- Evyn M. Peters
- Ann John
- Rudy Bowen
- Marilyn Baetz
- Lloyd Balbuena
1 Application
| Application ID | Title |
|---|---|
| 18046 | Personality and mental health characteristics of people attempting or dying from suicide |
Enabling scientific discoveries that improve human health