| Title: | Comprehensive risk assessment of chronic disease onset and outcome |
| Lead Institution: | International Agency for Research on Cancer |
| Principal investigator: |
Application 97846
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About
Scientific rationale: One in five people will develop a cancer during their lifetime. Cancer prevention has become one of the most important public health challenges of the 21st century. Based on current scientific evidence, at least 40% of all cancer cases can be prevented with effective prevention measures. It is also possible to save lives by detecting cancer earlier through screening when treatment is more likely to be successful. We believe that better methods to predict cancer can improve both cancer prevention and screening. Aims: We aim to develop a method that predicts cancer of any type. Public health impact: This project will provide a risk prediction model that can inform individuals their risk of developing any common cancer. It will allow individuals to understand the most effective ways they can reduce their risk, and also highlight if they may benefit from screening. Expected Project duration: 3 years5 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 15866 | Association between socioeconomic position and lung cancer incidence in 16 countries: a prospective cohort consortium study | Justina Ucheojor Onwuka (+41) | 2025 | EClinicalMedicine |
| 16823 | Exploring the Syndemic of Steatotic Liver Disease, Socioeconomic Inequities and Cancer Risk in the UK Biobank | Lucia Dansero (+5) | 2025 | Liver International |
| 9637 | Kidney function and risk of Renal Cell Carcinoma | Karine Alcala (+9) | 2023 | Cancer Epidemiology Biomarkers & Prevention |
| 16770 | Lymphocyte count and risk of chronic lymphocytic leukaemia | Simon Pahnke (+6) | 2025 | Journal of the National Cancer Institute |
| 18316 | Systematic assessment of obesity-related risk factors in renal cancer etiology: A longitudinal risk and mendelian randomization analysis | Karine Alcala (+12) | 2026 | PLOS Medicine |
Enabling scientific discoveries that improve human health