: Application

Application 91536

Title:	Understanding the association between mental health and all-cause mortality, and the role of environmental and lifestyle factors
Lead Institution:	Shandong University
Principal investigator:

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About

Mental health is an important risk factor for suicide and self-harm. People with mental health are in a lower status of life and a higher risk for adverse outcomes. Limited studies explore the all-cause mortality caused by mental health. At the same time, Interaction between mental health and environmental and/or lifestyle is needed to explore using large cohort. In this study, we need the data of Tier 1 and would like to apply data of mental health, lifestyle including physical activity, dietary behavior, sleep, sedentary behavior et al, environmental variables such as pollution, temperature et al and reason of death. Using the data of UKB, we will: 1) explore the association between mental health and all-cause mortality; 2) explore the association between mental health and all-cause mortality by environmental factors; 3) explore the association between mental health and all-cause mortality by lifestyle factors; 4) explore the risk of suicide attempt and suicide associated with mental health, environmental and lifestyle factors.

17 Publications

Pub ID	Title	Author(s)	Year	Journal
14518	Analysis of macular retinal thickness in polyarteritis nodosa using spectral domain optical coherence tomography	Che-Ning Yang (+2)	2025	Journal of Ophthalmic Inflammation and Infection
9897	Association and biological pathways between lung function and incident depression: a prospective cohort study of 280,032 participants	Wei Hu (+2)	2024	BMC Medicine
16579	Association between loneliness, social isolation and incident depression: a prospective study based on UK Biobank	Li-Peng Wan (+5)	2025	General Hospital Psychiatry
15863	Association of Life's Essential 8 with incidence of heart failure modified by depressive symptoms: a prospective cohort study from UK Biobank	Wei Hu (+7)	2025	BMC Medicine
12116	Associations and Mediating Pathways Between Childhood Adversity and Risk of Dementia: A Cohort Study in the UK Biobank	Wei Hu (+3)	2024	The Journals of Gerontology Series A
15675	Associations between shift work and biological age acceleration: A population-based study	Jia-Ning Wang (+3)	2025	GeroScience
16284	Associations of clinical biomarker-based biological aging with suicide attempts and suicidal ideation: evidence from 124,529 UK Biobank participants	Wei Hu (+4)	2025	Translational Psychiatry
14517	Associations of green and blue space and the natural environment with suicidal ideation: The role of psychiatric disorders	Tong-Jie Feng (+5)	2025	Environmental Research
15390	Composite lifestyle, genetic risk, blood biomarkers, and risk of suicide attempts: a prospective cohort study	Wei Hu (+7)	2025	Brain Behavior and Immunity
8947	Exposure to residential green and blue space and the natural environment is associated with a lower incidence of psychiatric disorders in middle-aged and older adults: findings from the UK Biobank	Bao-Peng Liu (+5)	2024	BMC Medicine
13394	Grip strength, genetic predisposition, and Incident Parkinson's disease: a prospective cohort study in the UK Biobank	Wei Hu (+4)	2024	npj Parkinson's Disease
12841	Replacement of sedentary behavior with various physical activities and the risk of incident depression: a prospective analysis of accelerator-measured and self-reported UK Biobank data	Jia-Hui Zhu (+3)	2024	Social Psychiatry and Psychiatric Epidemiology
10999	Shift work schedule and sleep patterns in relation to incident depression: Evidence from a prospective cohort study	Bao-Peng Liu (+1)	2023	Psychiatry Research
9480	The Impact of Physical Activity Intensity on the Dynamic Progression of Cardiometabolic Multimorbidity: Prospective Cohort Study Using UK Biobank Data	Bao-Peng Liu (+5)	2023	JMIR Public Health and Surveillance
7875	The associations of physical activity and lifetime depression with all-cause and cause-specific mortality: evidence from a prospective cohort study	Bao-Peng Liu (+1)	2023	Psychiatry Research
13057	The joint associations of physical activity and ultra-processed food consumption with depression: A cohort study in the UK Biobank	Zhen-Zhen Shen (+3)	2024	Journal of Affective Disorders
14449	Timing of physical activity, genetic predisposition, and incident depression: An accelerometer-based prospective cohort study	Ge Tian (+5)	2025	Journal of Affective Disorders

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